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Sulfamerazine sodium

Product Name
Sulfamerazine sodium
CAS No.
127-58-2
Chemical Name
Sulfamerazine sodium
Synonyms
Nsc226823;solumedine;sulfamerazine sodium;SODIUM SULFAMERAZINE;sodiumsulphamerazine;solublesulfamerazine;Pyrimidine sodium sulfa;SULFAMERAZINE SODIUM SALT;SulfadimidineSodium,Pharma;Sulfamerazine sodium USP/EP/BP
CBNumber
CB9289260
Molecular Formula
C11H13N4NaO2S
Formula Weight
288.3
MOL File
127-58-2.mol
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Sulfamerazine sodium Property

RTECS 
WP0760000
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Powder
Water Solubility 
Soluble in DMSO or water
CAS DataBase Reference
127-58-2(CAS DataBase Reference)
EPA Substance Registry System
Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, monosodium salt (127-58-2)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/22-36/38-36/37/38
Safety Statements 
7-24-45-36-26
WGK Germany 
3
TSCA 
Yes
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S0800
Product name
Sulfamerazine sodium salt
Packaging
250g
Price
$162
Updated
2024/03/01
Alfa Aesar
Product number
J66717
Product name
Sulfamerazine sodium salt
Packaging
250g
Price
$150
Updated
2024/03/01
Cayman Chemical
Product number
23380
Product name
Sulfamerazine (sodium salt)
Purity
≥98%
Packaging
10g
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
23380
Product name
Sulfamerazine (sodium salt)
Purity
≥98%
Packaging
50g
Price
$56
Updated
2024/03/01
Cayman Chemical
Product number
23380
Product name
Sulfamerazine (sodium salt)
Purity
≥98%
Packaging
100g
Price
$78
Updated
2024/03/01
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Sulfamerazine sodium Chemical Properties,Usage,Production

Description

Sulfamerazine is a sulfonamide antibiotic. It inhibits bacterial carbonic anhydrase by ~20% at a concentration of 500 μM. In vivo, sulfamerazine (500 mg/L) reduces severity of peribronchitis and inhibits cilia-associated respiratory Bacillus colonization in mice. It also prevents death of Toxoplasma-infected mice. Sulfonamide class antibiotics, of which sulfamerazine is a member, are bacteriostatic and inhibit bacterial synthesis of dihydrofolic acid by competing with 4-aminobenzoic acid for binding to dihydropteroate synthase. Formulations containing sulfamerazine have been used for the treatment of pneumonia and typhoid fever.

Uses

Involved in characterization of chirosan membranes for the transport of drugs1,2,3

brand name

Bio hubber simple;Cremo-merazine;Debnal m;Mebacid;Neotrizine;Peccocode;Septosil;Spanbolet ii;Tersulpha;Trisulfaminic;Trisulpha.

World Health Organization (WHO)

Sulfamerazine sodium, a sulfonamide anti-infective agent, was introduced several decades ago for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing resistance and their replacement by antibiotics which are generally more active and less toxic. The sulfonamides are known to cause serious adverse effects such as renal toxicity, sometimes fatal exfoliative dermatitis and erythema multiforma and dangerous adverse reactions affecting blood formation such as agranulocytosis and haemolytic or aplastic anaemia. Sulfamerazine is still used in some countries usually in combination with other sulfonamides.

Safety Profile

Moderately toxic by ingestion, subcutaneous, intraperitoneal, and intravenous routes. When heated to decomposition it emits toxic fumes of SOx, NOx, and Na2O.

Sulfamerazine sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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Sulfamerazine sodium Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from Sulfamerazine sodium manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Sulfamerazine Sodium 127-58-2
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-21
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Sulfamerazine Sodium 127-58-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-04-03
Baoji Guokang Healthchem co.,ltd
Product
Sulfamerazine sodium 127-58-2
Price
US $80.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
10000kg
Release date
2021-06-04

127-58-2, Sulfamerazine sodiumRelated Search:


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