6-((N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-HEXANOYL)SPHINGOSYL PHOSPHOCHOLINE
- Product Name
- 6-((N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-HEXANOYL)SPHINGOSYL PHOSPHOCHOLINE
- CAS No.
- 94885-04-8
- Chemical Name
- 6-((N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-HEXANOYL)SPHINGOSYL PHOSPHOCHOLINE
- Synonyms
- C6-Nbd-sm;C6-NBD-SPHINGOMYELIN;NBD C6-SPHINGOMYELIN;FLUORESCENT SPHINGOMYELIN;NBD-C12-L-Threo-sphingosine;C6 NBD Sphingomyelin (d18:1/6:0);NBD C6-Sphingomyelin DISCONTINUED;N-C6-NBD-SPHINGOSYLPHOSPHORYLCHOLINE;N-HEXANOYL-NBD-SPHINGOSYLPHOSPHORYLCHOLINE;N-Hexanoyl-NBD-D,L-sphingosylphosphorylcholine
- CBNumber
- CB9298721
- Molecular Formula
- C35H61N6O9P
- Formula Weight
- 740.88
- MOL File
- 94885-04-8.mol
6-((N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-HEXANOYL)SPHINGOSYL PHOSPHOCHOLINE Property
- storage temp.
- −20°C
- solubility
- Chloroform: Soluble; Ethanol: Soluble; Methanol: Soluble
- form
- A solid
- color
- Brown to orange
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- 24328
- Product name
- C6 NBD Sphingomyelin (d18:1/6:0)
- Purity
- ≥98%
- Packaging
- 100μg
- Price
- $195
- Updated
- 2024/03/01
- Product number
- 24328
- Product name
- C6 NBD Sphingomyelin (d18:1/6:0)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $456
- Updated
- 2024/03/01
- Product number
- LIP0004720
- Product name
- 6-((N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-HEXANOYL)SPHINGOSYL PHOSPHOCHOLINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.91
- Updated
- 2021/12/16
- Product number
- 8559CP
- Product name
- C6-Nbd-SM
- Packaging
- 1mg
- Price
- $584
- Updated
- 2021/12/16
6-((N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-HEXANOYL)SPHINGOSYL PHOSPHOCHOLINE Chemical Properties,Usage,Production
Description
C6 NBD sphingomyelin is a biologically active derivative of sphingomyelin (Item Nos. 22674 | 24345) that is tagged with a fluorescent C6 nitrobenzoxadiazole (C6 NBD; ) group. C6 NBD sphingomyelin has been used to study the metabolism and transport of sphingomyelins. It is degraded in the plasma membrane to C6 NBD ceramide by neutral sphingomyelinase, an enzyme with three-fold higher activity in undifferentiated HT29 cells than in differentiated cells. Unlike endogenous long-chain sphingomyelin and C6 sphingomyelin, C6 NBD sphingomyelin can be transported to the cell surface even in the presence of the vesicular transport inhibitor brefeldin A , but this transport can be blocked by multidrug resistance protein inhibitors in CHO cells. This product is a mixture of the D-erythro and L-threo isomers of sphingomyelin. [Matreya, LLC. Catalog No. 1912]
Uses
A probe that fluorescently labels membranous fatty acid phospholipids and has shown to excite the NBD group at 460 nm and emit at 534 nm.
6-((N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-HEXANOYL)SPHINGOSYL PHOSPHOCHOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
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