C2 CERAMIDE
- Product Name
- C2 CERAMIDE
- CAS No.
- 3102-57-6
- Chemical Name
- C2 CERAMIDE
- Synonyms
- N-ACETYLSPHINGOSINE;N-ACETYL-D-SPHINGOSINE;N-ETHANOYL-D-ERYTHRO-SPHINGOSINE;CERAMIDE C2;C2 CERAMIDE;C2:0 CERAMIDE;TOC Ceramide;ACETYL CERAMIDE;C14 SPHINGOID BASE;N-Acetylsphigosine
- CBNumber
- CB8342539
- Molecular Formula
- C20H39NO3
- Formula Weight
- 341.53
- MOL File
- 3102-57-6.mol
C2 CERAMIDE Property
- Melting point:
- 93-96 °C
- Boiling point:
- 477.13°C (rough estimate)
- Density
- 1.0283 (rough estimate)
- refractive index
- 1.5614 (estimate)
- storage temp.
- −20°C
- solubility
- DMSO: soluble
- form
- powder
- pka
- 13.50±0.20(Predicted)
- color
- white
- biological source
- semisynthetic
- Stability:
- Moisture Sensitive
- InChI
- InChI=1S/C20H39NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(24)19(17-22)21-18(2)23/h15-16,19-20,22,24H,3-14,17H2,1-2H3,(H,21,23)/b16-15+/t19-,20+/m0/s1
- InChIKey
- BLTCBVOJNNKFKC-QUDYQQOWSA-N
- SMILES
- C(N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC)(=O)C
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 29241990
N-Bromosuccinimide Price
- Product number
- A7191
- Product name
- <I>N</I>-Acetyl-D-sphingosine
- Purity
- ≥97% (TLC), powder
- Packaging
- 1 mg
- Price
- $39.4
- Updated
- 2025/07/31
- Product number
- A7191
- Product name
- <I>N</I>-Acetyl-D-sphingosine
- Purity
- ≥97% (TLC), powder
- Packaging
- 5 mg
- Price
- $105
- Updated
- 2025/07/31
- Product number
- 01912
- Product name
- <I>N</I>-Acetyl-D-sphingosine
- Purity
- ≥98.0% (TLC)
- Packaging
- 50 mg
- Price
- $182.7
- Updated
- 2025/07/31
- Product number
- 01912
- Product name
- <I>N</I>-Acetyl-D-sphingosine
- Purity
- ≥98.0% (TLC)
- Packaging
- 250 mg
- Price
- $881
- Updated
- 2025/07/31
- Product number
- 01912
- Product name
- N-Acetyl-D-sphingosine
- Purity
- ≥98.0% (TLC)
- Packaging
- 50mg
- Price
- $101.6
- Updated
- 2024/03/01
C2 CERAMIDE Chemical Properties,Usage,Production
Description
C2 ceramide is a cell-
Chemical Properties
White Crystalline Solid
Uses
Inhibits cell proliferation and induces monocytic differentiation of HL-60 cells. Activates protein phosphatases
Uses
A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2
Definition
ChEBI: N-acetylsphingosine is a N-acylsphingosine that has an acetamido group at position 2.
Biological Activity
A potent modulator of cell proliferation and differentiation. Activates protein phosphatase-1 (PP1) and -2A (PP2A), as well as ceramide-activated protein phosphatase (CAPP) in vitro .
Biochem/physiol Actions
Cell-permeable, biologically active ceramide. It induces differentiation and apoptosis in cells and has been shown to activate protein phosphatases.
storage
Desiccate at -20°C
References
[1] ALFREDO MIÑANO. C2-ceramide mediates cerebellar granule cells apoptosis by activation of caspases-2, -9, and -3[J]. Journal of Neuroscience Research, 2008, 86 8: 1734-1747. DOI:10.1002/jnr.21633
[2] ALESSANDRO PRINETTI. Involvement of a ceramide activated protein phosphatase in the differentiation of neuroblastoma Neuro2a cells[J]. FEBS Letters, 1997, 414 2: Pages 475-479. DOI:10.1016/s0014-5793(97)00981-2
[3] Y ZHANG. Kinase suppressor of Ras is ceramide-activated protein kinase.[J]. Cell, 1997, 89 1: 63-72. DOI:10.1016/s0092-8674(00)80183-x
[4] Y. MATSUZAKA. Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx Mice[J]. PLoS ONE, 2016, 11 1. DOI:10.1371/journal.pone.0167811
[5] Y. MATSUZAKA. Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx Mice[J]. PLoS ONE, 2016, 11 1. DOI:10.1371/journal.pone.0167811
C2 CERAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
C2 CERAMIDE Suppliers
- Tel
- 021-61150625 17721318029
- Fax
- 021-26018649
- info@renshipharma.com
- Country
- China
- ProdList
- 161
- Advantage
- 55
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 12952
- Advantage
- 65
- Tel
- 800-810-5118
- Fax
- +86-10-84193589
- cnchemical@thermofisher.com
- Country
- China
- ProdList
- 17770
- Advantage
- 75
- Tel
- 020-39119399 18927568969
- Fax
- 020-39119999
- isunpharm@qq.com
- Country
- China
- ProdList
- 4720
- Advantage
- 55
- Tel
- +1 (866) 930-6790
- Fax
- +1 (866) 333-9607
- info@adooq.com
- Country
- United States
- ProdList
- 2782
- Advantage
- 58
View Lastest Price from C2 CERAMIDE manufacturers
- Product
- C2 CERAMIDE 3102-57-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-11