C2 CERAMIDE
- Product Name
- C2 CERAMIDE
- CAS No.
- 3102-57-6
- Chemical Name
- C2 CERAMIDE
- Synonyms
- N-ACETYLSPHINGOSINE;N-ACETYL-D-SPHINGOSINE;N-ETHANOYL-D-ERYTHRO-SPHINGOSINE;CERAMIDE C2;C2 CERAMIDE;C2:0 CERAMIDE;TOC Ceramide;ACETYL CERAMIDE;C14 SPHINGOID BASE;N-Acetylsphigosine
- CBNumber
- CB8342539
- Molecular Formula
- C20H39NO3
- Formula Weight
- 341.53
- MOL File
- 3102-57-6.mol
C2 CERAMIDE Property
- Melting point:
- 93-96 °C
- Boiling point:
- 477.13°C (rough estimate)
- Density
- 1.0283 (rough estimate)
- refractive index
- 1.5614 (estimate)
- storage temp.
- −20°C
- solubility
- DMSO: soluble
- form
- powder
- pka
- 13.50±0.20(Predicted)
- color
- white
- Stability:
- Moisture Sensitive
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 29241990
N-Bromosuccinimide Price
- Product number
- 01912
- Product name
- N-Acetyl-D-sphingosine
- Purity
- ≥98.0% (TLC)
- Packaging
- 50mg
- Price
- $101.6
- Updated
- 2024/03/01
- Product number
- 01912
- Product name
- N-Acetyl-D-sphingosine
- Purity
- ≥98.0% (TLC)
- Packaging
- 250mg
- Price
- $342.8
- Updated
- 2024/03/01
- Product number
- J60534
- Product name
- N-Acetyl-D-sphingosine, 98%
- Packaging
- 5mg
- Price
- $112
- Updated
- 2023/06/20
- Product number
- J60534
- Product name
- N-Acetyl-D-sphingosine, 98%
- Packaging
- 1mg
- Price
- $20.5
- Updated
- 2021/12/16
- Product number
- 62510
- Product name
- C-2 Ceramide
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $21
- Updated
- 2024/03/01
C2 CERAMIDE Chemical Properties,Usage,Production
Description
C2 ceramide is a cell-
Chemical Properties
White Crystalline Solid
Uses
Inhibits cell proliferation and induces monocytic differentiation of HL-60 cells. Activates protein phosphatases
Uses
A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2
Definition
ChEBI: N-acetylsphingosine is a N-acylsphingosine that has an acetamido group at position 2.
Biological Activity
A potent modulator of cell proliferation and differentiation. Activates protein phosphatase-1 (PP1) and -2A (PP2A), as well as ceramide-activated protein phosphatase (CAPP) in vitro .
Biochem/physiol Actions
Cell-permeable, biologically active ceramide. It induces differentiation and apoptosis in cells and has been shown to activate protein phosphatases.
storage
Desiccate at -20°C
References
1) Minano et al. (2008), C2-ceramide mediates cerebellar granule cells apoptosis by activation of caspases-2, -9, and -3; J. Neurosci. Res., 86 1734 2) Prinetti et al. (1997), Involvement of a ceramide activated protein phosphatase in the differentiation of neuroblastoma Neuro2a cells; FEBS Lett., 414 475 3) Zhang et al. (1997), Kinase suppressor of Ras is ceramide-activated protein kinase; Cell, 89 63 4) Matsuzaka et al. (2016) Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx Mice; PLoS One 11(12) e0167811 [Focus Biomolecules Citation] 5) Matsuzaka et al. (2016) Characterization and functional analysis of extracellular vesicles and muscle-abundant miRNA in C2C12 myocytes and Mdx mice; PLoS One 11(12) e0167811 [Focus Biomolecules Citation]
C2 CERAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
C2 CERAMIDE Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71
View Lastest Price from C2 CERAMIDE manufacturers
- Product
- C2 CERAMIDE 3102-57-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-11