Tetrabenzyl pyrophosphate

Product Name: Tetrabenzyl pyrophosphate
CAS No.: 990-91-0
Chemical Name: Tetrabenzyl pyrophosphate
Synonyms: PYROPHOSPHORIC ACID TETRABENZYL ESTER;TETRABENZYL DIPHOSPHATE;C2gH2gO7P2;TetrabenzyL;Bis(phenylmethox;Benzyl Pyrophosphate;Tetracyl pyrophosphate;Tetrabenzyl yrophosphate;Fosaprepitant Impurity S;Tetrabenzyl Pyrophosphte
CBNumber: CB9300303
Molecular Formula: C28H28O7P2
Formula Weight: 538.47
MOL File: 990-91-0.mol

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Tetrabenzyl pyrophosphate Property

Melting point:: 63-66 °C (lit.)
Boiling point:: 601.6±55.0 °C(Predicted)
Density: 1.289±0.06 g/cm3(Predicted)
vapor pressure: 0.001Pa at 140℃
storage temp.: -20°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Powder or Crystalline Powder
color: White to off-white
Water Solubility: Slightly soluble in water.
Sensitive: Moisture Sensitive
BRN: 2068292
InChI: InChI=1S/C28H28O7P2/c29-36(31-21-25-13-5-1-6-14-25,32-22-26-15-7-2-8-16-26)35-37(30,33-23-27-17-9-3-10-18-27)34-24-28-19-11-4-12-20-28/h1-20H,21-24H2
InChIKey: NSBNXCZCLRBQTA-UHFFFAOYSA-N
SMILES: P(=O)(OCC1C=CC=CC=1)(OCC1C=CC=CC=1)OP(=O)(OCC1C=CC=CC=1)OCC1C=CC=CC=1
CAS DataBase Reference: 990-91-0(CAS DataBase Reference)

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Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 26-36/37/39-45
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
F: 10-21
HazardClass: 8
PackingGroup: II
HS Code: 29209090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 418633
Product name: Tetrabenzyl pyrophosphate
Purity: 98%
Packaging: 1g
Price: $323
Updated: 2024/03/01

TCI Chemical

Product number: P1223
Product name: Tetrabenzyl Pyrophosphate
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $70
Updated: 2024/03/01

Alfa Aesar

Product number: L09083
Product name: Tetrabenzyl pyrophosphate, 98%
Packaging: 1g
Price: $217
Updated: 2024/03/01

Alfa Aesar

Product number: L09083
Product name: Tetrabenzyl pyrophosphate, 98%
Packaging: 5g
Price: $801
Updated: 2024/03/01

Alfa Aesar

Product number: L09083
Product name: Tetrabenzyl pyrophosphate, 98%
Packaging: 250mg
Price: $64.8
Updated: 2021/12/16

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Tetrabenzyl pyrophosphate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Tetrabenzyl pyrophosphate is used in the preparation of phosphoryl derivatives of shikimic acid in the presence of LDA. It is used in the preparation of dibenzyl phosphoro fluoridate in the presence of cesium fluoride as a catalyst. It is also used as a precursor in pharmaceuticals and involved in the phosphorylation of inositol derivatives.

Uses

Phosphorylating reagent.

Preparation

The production of tetrabenzyl pyrophosphate by the action of acyl chlorides on dibenzyl hydrogen phosphate, and a novel reaction of tetraphenyl pyrophosphate.
Preparation of Tetrabenzyl Pyrophosphate: A flask fitted with a nitrogen inlet, overhead stirrer, teflon-coated thermocouple probe, and pressure-equalizing addition funnel was charged with 350 milliliters of dry (water content ≦50 μg/mL), peroxide-free tetrahydrofuran, followed by 50.0 grams (174 millimoles) of dibenzylphosphoric acid (DBP), and the resulting mixture was stirred until the solid dissolved (about 10-15 minutes). A solution of 18.9 grams (91.6 millimoles) of dicyclohexylcarbodiimide (DCC) in 215 milliliters of THF was added from the addition funnel to a stirred, cooled (water-bath) solution of DBP at a rate to maintain the temperature at about 20°-25° C. The reaction is slightly exothermic and the addition took about 30 minutes. Within minutes, a precipitate of dicyclohexylurea formed in the mixture. Stirring was continued for about 2 hours at 20°-25° C. The reaction was monitored by HPLC assay using VYDAC C-18 (300A, 4.6×250 mm) column with water (0.02M KH2PO4) acetonitrile as eluent. The reaction was complete in about 1 hour (assay showing <2 percent unreacted DBP). The mixture was then filtered while excluding moisture to remove dicyclohexylurea. The filter cake was washed with two 25 milliliter portions of THF. The solution when assayed by HPLC showed 45.9 grams (98 percent) yield of tetrabenzyl pyrophosphate (TBPP) in 620 milliliters of THF (0.137M). The filtrate was then stored at 0° C. with exclusion of moisture until the next step.

Tetrabenzyl pyrophosphate Preparation Products And Raw materials

Raw materials

Heptane Dibenzyl phosphate Isopropyl acetate Dicyclohexylcarbodiimide

Preparation Products

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Tetrabenzyl pyrophosphate Suppliers

Americas 1 Canada 3 China 254 Europe 1 France 2 Germany 6 India 15 Italy 1 Japan 2 Poland 1 Slovakia 1 Switzerland 1 United Kingdom 6 United States 16 Global 310

Wuhan Circle Star Chem-medic Technology Co.,Ltd

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ShangHai DEMO Chemical Co.,Ltd

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Energy Chemical

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View Lastest Price from Tetrabenzyl pyrophosphate manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: TETRABENZYL DIPHOSPHATE 990-91-0
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-19

Hebei Chuanghai Biotechnology Co,.LTD

Product: Tetrabenzyl Pyrophosphate 990-91-0
Price: US $11.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-21

Hebei Mojin Biotechnology Co., Ltd

Product: TETRABENZYL DIPHOSPHATE 990-91-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-09-01

990-91-0, Tetrabenzyl pyrophosphateRelated Search:

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PYROPHOSPHORIC ACID TETRABENZYL ESTER

TETRABENZYL PYROPHOSPHATE

TETRABENZYL DIPHOSPHATE

Tetrabenzyl pyrophosphate, tech.

Pyrophosphoric acid tetrabenzyl ester, Tetrabenzyl diphosphate

Bis(phenylmethoxy)phosphoryl bis(phenylmethyl) phosphate

Benzyl Pyrophosphate

Diphosphoric Acid P,P,P',P'-Tetrakis(phenylMethyl) Ester

Tetrabenzyl yrophosphate

Bis(phenylmethox

Tetrabenzyl pyrophosphate Pyrophosphoric acid tetrabenzyl ester

Tetrabenzyl pyrophosphate 98%

dibenzyl {[bis(benzyloxy)phosphoryl]oxy}phosphonate

yrophosphoric acid tetrabenzyl ester

TetrabenzylPyrophosphate&gt

Tetrabenzyl pyrophosphate, 99%, for synthesis

TetrabenzyL

Tetrabenzylpyrophosphate (TBPP)

TETRABENZYL PYROPHOSPHATE 990-91-0

Creatine Phosphate Impurity 21（Tetrabenzyl Diphosphate）

Fosaprepitant Impurity S

Tetrabenzyl Pyrpophosphate

dibenzyl bis(phenylmethoxy)phosphoryl phosphate

Tetracyl pyrophosphate

P,P,P',P'-Tetrakis(phenylmethyl) (diphosphate)

Tetrabenzyl Pyrophosphte

C2gH2gO7P2

990-91-0

C28H28O7P2

C6H5CH2O2POOPOOCH2C6H52

Building Blocks

Organic Phosphates/Phosphites

Phosphorus Compounds

Organic Building Blocks

DNA / RNA Synthesis

Phosphorylation

Phosphorylating Agents

Phosphorylating and Phosphitylating Agents

Biochemistry

Nucleosides, Nucleotides & Related Reagents

Phosphorylating and Phosphorothioating Agents

Phosphorylation

Protecting Agents, Phosphorylating Agents & Condensing Agents

Synthetic Organic Chemistry