IBOGAINE
- Product Name
- IBOGAINE
- CAS No.
- 83-74-9
- Chemical Name
- IBOGAINE
- Synonyms
- Ibogain;IBOGAINE;endabuse;Ibogaine solution;12-Methoxyibogamine;12-methoxy-ibogamin;Ibogamine, 12-methoxy-;TIANFU CHEM-- IBOGAINE;IbogaineQ: What is Ibogaine Q: What is the CAS Number of Ibogaine;6,9-Methano-5H-pyrido[1',2':1,2]azepino[4,5-b]indole, ibogamine deriv.
- CBNumber
- CB9300459
- Molecular Formula
- C20H26N2O
- Formula Weight
- 310.43
- MOL File
- 83-74-9.mol
IBOGAINE Property
- Melting point:
- 152-153°
- alpha
- D20 -53° (in 95% ethanol)
- Boiling point:
- 450.59°C (rough estimate)
- Density
- 1.0633 (rough estimate)
- refractive index
- 1.6800 (estimate)
- storage temp.
- 2-8°C
- pka
- 8.1 in 80% methylcellosolve
- EPA Substance Registry System
- Ibogaine (83-74-9)
Safety
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-39/23/24/25
- Safety Statements
- 7-16-36/37-45
- RIDADR
- 1544
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Hazardous Substances Data
- 83-74-9(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- API0009325
- Product name
- IBOGAINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.92
- Updated
- 2021/12/16
- Product number
- CFN97329
- Product name
- Ibogaine
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $293
- Updated
- 2021/12/16
IBOGAINE Chemical Properties,Usage,Production
Description
This indole alkaloid occurs in the root of Tabernanthe iboga Baill. It was first
examined in detail by Raymond-Hamet who assigned to it the empirical formula
C19H24(26)ON2, now altered to that given above. The base forms colourless
crystals from EtOH and is laevorotatory with [Q1D - 53° (EtOH). It is insoluble
in Et20, slightly so in Me2CO or CHC1 3 but dissolves freely in MeOH, EtOH or
H20. The alkaloid yields a hydrochloride, m.p. 299°C (dec.); lQlhs - 67°
(MeOH) or - 37.3° (H20). It contains one methoxyl group and gives the typical
indole reactions. On distillation with Zn dust or soda-lime it furnishes products
which are indole derivatives with the ~-position free.
In a manner similar to that of cocaine, the alkaloid potentiates the pressor
action of adrenaline and abolishes the sino-carotid reflexes. Unlike cocaine,
however, it also augments the action of tyramine and that of dl-ephedrine to a
slight extent. Vincent and Sero have reported that it inhibits the action of serum
cholinesterase.
Definition
ChEBI: Ibogaine is an organic heteropentacyclic compound that is ibogamine in which the indole hydrogen para to the indole nitrogen has been replaced by a methoxy group. It has a role as a plant metabolite, an inhibitor, a hallucinogen and a oneirogen. It is a monoterpenoid indole alkaloid, an organic heteropentacyclic compound and an aromatic ether. It is functionally related to an ibogamine. It is a conjugate base of an ibogaine(1+).
Purification Methods
Crystallise it from EtOH or aqueous EtOH and sublime it at 150o/0.01mm. It is soluble in organic solvents but insoluble in H2O. The hydrochloride, m 299-300o(dec), is soluble in H2O and alcohols. [Büchi et al. J Am Chem Soc 88 3099 1866, Rosenmund Chem Ber 108 1871 1975, Beilstein 23 III/IV 2742.]
References
Raymond-Hamet., Bull. Soc. Chirn. Fr., 9,620 (1942)
Delourme-Houde., Chern. Abstr., 41, 1390 (1947)
Bartlett, Dickel, Taylor.,J. Arner. Chern. Soc., 80, 126 (1958)
Arai, Coppola, Jeffery., Acta Cryst., 13, 553 (1960)
Shamma, Soyster., Experientia, 20,36 (1964)
Synthesis:
Buchi et ai., f. Arner. Chern. Soc., 88,3099 (1966)
Pharmacology:
Raymond-Hamet, Rothlin., C.R. Soc. Bioi., 127,592 (1938)
Raymond-Hamet, Rothlin., Arch. inst. Pharrnacodyn., 63, 27 (1939)
Raymond-Hamet., Cornpt. rend., 201,285 (1940)
Raymond-Hamet., C.R. Soc. Bioi., 135, 176 (1941)
Raymond-Hamet, Perrot., Bull. Acad. Med., 24,423 (1941)
Vincent, Sero., C.R. Soc. Bioi., 136,612 (1942)
IBOGAINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from IBOGAINE manufacturers
- Product
- IBOGAINE 83-74-9
- Price
- US $3014.00-2500.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 5000g
- Release date
- 2023-09-15
- Product
- IBOGAINE 83-74-9
- Price
- US $500.00-300.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100Tons
- Release date
- 2023-10-10