LENAMPICILLIN HYDROCHLORIDE

Product Name: LENAMPICILLIN HYDROCHLORIDE
CAS No.: 80734-02-7
Chemical Name: LENAMPICILLIN HYDROCHLORIDE
Synonyms: kb1585;kbt1585;kbt-1585;varacillin;takacillin;LENAMPICILLIN;LenampicillinHCl;KBT-1585 HYDROCHLORIDE;Lempicillin hydrochloride;Lenanpicillin hydrochloride
CBNumber: CB9302877
Molecular Formula: C21H23N3O7S
Formula Weight: 461.49
MOL File: 80734-02-7.mol

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LENAMPICILLIN HYDROCHLORIDE Property

Melting point:: 145° (dec)
storage temp.: Store at -20°C, sealed storage, away from moisture and light
solubility: DMSO:100.0(Max Conc. mg/mL);200.82(Max Conc. mM)
form: Solid
color: White to off-white

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Safety

Toxicity: LD50 in male, female rats, male, female mice (mg/kg): approx 10000, approx 10000, 8294, 8492 orally; 4362, 4471, 3576, 4284 s.c.; 876, 838, 711, 775 i.v.; in dogs (mg/kg): >300 orally (Ogino)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: L328100
Product name: LenampicillinHydrochloride
Packaging: 10mg
Price: $165
Updated: 2021/12/16

Usbiological

Product number: 281219
Product name: Lenampicillin hydrochloride
Packaging: 5mg
Price: $460
Updated: 2021/12/16

TRC

Product number: L328100
Product name: LenampicillinHydrochloride
Packaging: 100mg
Price: $1320
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0025153
Product name: LENAMPICILLIN HYDROCHLORIDE
Purity: 95.00%
Packaging: 5MG
Price: $497.49
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 47096
Product name: LenampicillinHCl
Packaging: 10mg
Price: $650
Updated: 2021/12/16

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LENAMPICILLIN HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Lenampicillin is an oral ampicillin prodrug. Antibiotic used in the treatment of respiratory tract infections and urinary tract infections.

Definition

ChEBI: Valacillin (TN) is a peptide.

in vivo

Lenampicillin hydrochloride (KBT-1585) (oral adminstration; 0-1000 mg/kg) does not lead to death in dogs, and maximum dose of in this acute toxicity study is recorded because of causing emesis^[2].Lenampicillin hydrochloride (LAPC) are identified for it main metabolites in rat and dogs. The main metabolite in peripheral plasma is 2,3-butanediol in rats and dog, On the other hand, high levels of acetoin is found in portal plasma for early period after dosing of LAPC. These results shows that the biotransformation of promoiety in LAPC to acetoin carried out mainly in intestinal tissues, but acetoin is converted to 2,3-butanediol in liver^[3].

LENAMPICILLIN HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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LENAMPICILLIN HYDROCHLORIDE Suppliers

China 31 Europe 2 Germany 1 United Kingdom 4 United States 8 Global 46

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80734-02-7, LENAMPICILLIN HYDROCHLORIDERelated Search:

L-Cysteine ethyl ester hydrochloride D-VALINE METHYL ESTER HYDROCHLORIDE LENAMPICILLIN,LENAMPICILLIN HYDROCHLORIDE Vinylene carbonate ETHYL 3-(METHYLTHIO)BUTYRATE DL-VALINE ETHYL ESTER HYDROCHLORIDE 4,5-Dimethyl-1,3-dioxol-2-one Ampicillin H-D-VAL-OET HCL 4-METHOXY-2-METHYL-2-BUTANETHIOL D-PENCILLAMINE METHYL ESTER HYDROCHLORIDE H-GLY-GLY-GLY-OET HCL 2-HYDROXYETHYL 3-MERCAPTOPROPIONATE 1,4-Thiazepane hydrochloride D(-)PENICILLAMINE HYDROCHLORIDE TRIMETHYLAMMONIUM FORMIATE METHYL 2-AMINO-3-MERCAPTOPROPANOATE HYDROCHLORIDE LENAMPICILLIN HYDROCHLORIDE

(5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl-d-alpha-aminobenzylpenicillinatehyd

-2-carboxylicacid,hydrochloride

-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane

ampicillin,(5-methyl-2-oxo-1,3-dioxolen-4-yl)methylester,hydrochloride

carbonicacid,cyclic1-(hydroxymethyl)-2-methylethyleneester,esterwith6-(2

kb1585

kbt1585

kbt-1585

takacillin

varacillin

(2S,5R,6R)-6-[[(2R)-AMinophenylacetyl]aMino]-3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)Methyl Ester Hydrochloride

[2S-[2α,5α,6β(S*)]]-6-[(AMinophenylacetyl)aMino]-3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)Methyl Ester MonoHydrochloride

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester, monohydrochloride, [2S-[2a,5a,6b(S*)]]-

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester, monohydrochloride, (2S,5R,6R)- (9CI)

Lenanpicillin hydrochloride

LENAMPICILLIN

LenampicillinHCl

LENAMPICILLIN HYDROCHLORIDE

Lenampicillin hydrochloride (KBT-1585 hydrochloride)

KBT-1585 HYDROCHLORIDE

Lempicillin hydrochloride

80734-02-7

C21H23N3O7S

Amines

Drug Analogues

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

Sulfur & Selenium Compounds