Mes-PEG5- t-butyl ester

Product Name: Mes-PEG5- t-butyl ester
CAS No.: 870487-48-2
Chemical Name: Mes-PEG5- t-butyl ester
Synonyms: CAS_870487-48-2;Mes-PEG4-t-butyl ester;MS-PEG5- t-butyl ester;Mes-PEG5- t-butyl ester;tert-Butyl 1-(Methylsulfonyloxy)-3,6,9,12-tetraoxapentadecan-15-oate;3,6,9,12,15-Pentaoxa-2-thiaoctadecan-18-oic acid, 1,1-dimethylethylester, 2,2-dioxide;4,7,10,13,16-Pentaoxa-17-thiaoctadecanoic acid, 1,1-dimethylethyl ester, 17,17-dioxide
CBNumber: CB93048723
Molecular Formula: C16H32O9S
Formula Weight: 400.48
MOL File: 870487-48-2.mol

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Mes-PEG5- t-butyl ester Property

Boiling point:: 499.9±40.0 °C(Predicted)
Density: 1.147±0.06 g/cm3(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-20516
Product name: Ms-PEG4-t-butylester
Purity: 98%
Packaging: 500mg
Price: $350
Updated: 2021/12/16

BroadPharm

Product number: BP-20516
Product name: Ms-PEG4-t-butylester
Purity: 98%
Packaging: 1g
Price: $620
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1521
Product name: Mes-PEG4-t-butyl ester
Packaging: 500mg
Price: $681
Updated: 2021/12/16

BroadPharm

Product number: BP-20516
Product name: Ms-PEG4-t-butylester
Purity: 98%
Packaging: 2g
Price: $930
Updated: 2021/12/16

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Mes-PEG5- t-butyl ester Chemical Properties,Usage,Production

Description

Ms-PEG4-t-butyl ester is a PEG linker with a mesyl group and a t-butyl protecting group. Mesyl is a good leaving group and can participate in substitution reactions. The t-butyl group can be removed under acidic condtions. The hydrophilic PEG linker increases the solubility properties of compounds in aqueous media.

Uses

Ms-PEG5-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mes-PEG5- t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Mes-PEG5- t-butyl ester Suppliers

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870487-48-2, Mes-PEG5- t-butyl esterRelated Search:

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Mes-PEG5- t-butyl ester

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CAS_870487-48-2

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tert-Butyl 1-(Methylsulfonyloxy)-3,6,9,12-tetraoxapentadecan-15-oate

870487-48-2

C16H32O9S