ChemicalBook > CAS DataBase List > Mes-PEG5- t-butyl ester

Mes-PEG5- t-butyl ester

Product Name
Mes-PEG5- t-butyl ester
CAS No.
870487-48-2
Chemical Name
Mes-PEG5- t-butyl ester
Synonyms
CAS_870487-48-2;Mes-PEG4-t-butyl ester;MS-PEG5- t-butyl ester;Mes-PEG5- t-butyl ester;tert-Butyl 1-(Methylsulfonyloxy)-3,6,9,12-tetraoxapentadecan-15-oate;3,6,9,12,15-Pentaoxa-2-thiaoctadecan-18-oic acid, 1,1-dimethylethylester, 2,2-dioxide;4,7,10,13,16-Pentaoxa-17-thiaoctadecanoic acid, 1,1-dimethylethyl ester, 17,17-dioxide
CBNumber
CB93048723
Molecular Formula
C16H32O9S
Formula Weight
400.48
MOL File
870487-48-2.mol
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Mes-PEG5- t-butyl ester Property

Boiling point:
499.9±40.0 °C(Predicted)
Density 
1.147±0.06 g/cm3(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-20516
Product name
Ms-PEG4-t-butylester
Purity
98%
Packaging
500mg
Price
$350
Updated
2021/12/16
BroadPharm
Product number
BP-20516
Product name
Ms-PEG4-t-butylester
Purity
98%
Packaging
1g
Price
$620
Updated
2021/12/16
Apolloscientific
Product number
BIPG1521
Product name
Mes-PEG4-t-butyl ester
Packaging
500mg
Price
$681
Updated
2021/12/16
BroadPharm
Product number
BP-20516
Product name
Ms-PEG4-t-butylester
Purity
98%
Packaging
2g
Price
$930
Updated
2021/12/16
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Mes-PEG5- t-butyl ester Chemical Properties,Usage,Production

Description

Ms-PEG4-t-butyl ester is a PEG linker with a mesyl group and a t-butyl protecting group. Mesyl is a good leaving group and can participate in substitution reactions. The t-butyl group can be removed under acidic condtions. The hydrophilic PEG linker increases the solubility properties of compounds in aqueous media.

Uses

Ms-PEG5-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mes-PEG5- t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Mes-PEG5- t-butyl ester Suppliers

A.J Chemicals
Tel
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Fax
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Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58

870487-48-2, Mes-PEG5- t-butyl esterRelated Search:


  • Mes-PEG5- t-butyl ester
  • MS-PEG5- t-butyl ester
  • Mes-PEG4-t-butyl ester
  • CAS_870487-48-2
  • 4,7,10,13,16-Pentaoxa-17-thiaoctadecanoic acid, 1,1-dimethylethyl ester, 17,17-dioxide
  • 3,6,9,12,15-Pentaoxa-2-thiaoctadecan-18-oic acid, 1,1-dimethylethylester, 2,2-dioxide
  • tert-Butyl 1-(Methylsulfonyloxy)-3,6,9,12-tetraoxapentadecan-15-oate
  • 870487-48-2
  • C16H32O9S