Mal-PEG1-acid

Product Name: Mal-PEG1-acid
CAS No.: 760952-64-5
Chemical Name: Mal-PEG1-acid
Synonyms: Mal-PEG1-acid;Mal-PEG1-CH2CH2COOH;3-[2-(2,5-dioxopyrrol-1-yl)ethoxy]propanoic acid;3-[2-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)ethoxy]propanoic Acid;3-[2-(2,5-Dioxo-2,5-dihydro-1h-pyrrol-1-yl)ethoxy]propanoic acid;Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-;Mal-PEG1-CH2CH2COOH/Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-
CBNumber: CB93062525
Molecular Formula: C9H11NO5
Formula Weight: 213.19
MOL File: 760952-64-5.mol

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Mal-PEG1-acid Property

Boiling point:: 419.4±30.0 °C(Predicted)
Density: 1.383±0.06 g/cm3(Predicted)
pka: 4.27±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: M158213
Product name: Mal-PEG1-acid
Packaging: 50mg
Price: $330
Updated: 2021/12/16

ChemScene

Product number: CS-0108926
Product name: Mal-PEG1-acid
Packaging: 250mg
Price: $520
Updated: 2021/12/16

BroadPharm

Product number: BP-21859
Product name: Mal-PEG1-acid
Purity: 98%
Packaging: 250mg
Price: $575
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1491
Product name: Mal-PEG1-acid
Packaging: 100mg
Price: $669
Updated: 2021/12/16

ChemScene

Product number: CS-0108926
Product name: Mal-PEG1-acid
Packaging: 100mg
Price: $300
Updated: 2021/12/16

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Mal-PEG1-acid Chemical Properties,Usage,Production

Description

Mal-PEG1-acid is a PEG linker containing a maleimide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Biological Activity

Mal-PEG1-acid is a non-cleavable ADC linker containing 1 unit PEG, which can be used to synthesize antibody drug conjugates (ADC),it is a PROTAC linker belonging to the PEG class, which can be used to synthesize PROTAC molecules.

in vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

PEGs	Non-cleavable

Mal-PEG1-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG1-acid Suppliers

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View Lastest Price from Mal-PEG1-acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Mal-PEG1-acid 760952-64-5
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 5g
Release date: 2024-03-27

760952-64-5, Mal-PEG1-acidRelated Search:

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Mal-PEG1-acid

Mal-PEG1-CH2CH2COOH

3-[2-(2,5-Dioxo-2,5-dihydro-1h-pyrrol-1-yl)ethoxy]propanoic acid

Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-

Mal-PEG1-CH2CH2COOH/Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-

3-[2-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)ethoxy]propanoic Acid

3-[2-(2,5-dioxopyrrol-1-yl)ethoxy]propanoic acid

760952-64-5