ChemicalBook > CAS DataBase List > Mal-PEG1-acid

Mal-PEG1-acid

Product Name
Mal-PEG1-acid
CAS No.
760952-64-5
Chemical Name
Mal-PEG1-acid
Synonyms
Mal-PEG1-acid;Mal-PEG1-CH2CH2COOH;3-[2-(2,5-dioxopyrrol-1-yl)ethoxy]propanoic acid;3-[2-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)ethoxy]propanoic Acid;3-[2-(2,5-Dioxo-2,5-dihydro-1h-pyrrol-1-yl)ethoxy]propanoic acid;Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-;Mal-PEG1-CH2CH2COOH/Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-
CBNumber
CB93062525
Molecular Formula
C9H11NO5
Formula Weight
213.19
MOL File
760952-64-5.mol
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Mal-PEG1-acid Property

Boiling point:
419.4±30.0 °C(Predicted)
Density 
1.383±0.06 g/cm3(Predicted)
pka
4.27±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
M158213
Product name
Mal-PEG1-acid
Packaging
50mg
Price
$330
Updated
2021/12/16
ChemScene
Product number
CS-0108926
Product name
Mal-PEG1-acid
Packaging
250mg
Price
$520
Updated
2021/12/16
BroadPharm
Product number
BP-21859
Product name
Mal-PEG1-acid
Purity
98%
Packaging
250mg
Price
$575
Updated
2021/12/16
Apolloscientific
Product number
BIPG1491
Product name
Mal-PEG1-acid
Packaging
100mg
Price
$669
Updated
2021/12/16
ChemScene
Product number
CS-0108926
Product name
Mal-PEG1-acid
Packaging
100mg
Price
$300
Updated
2021/12/16
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Mal-PEG1-acid Chemical Properties,Usage,Production

Description

Mal-PEG1-acid is a PEG linker containing a maleimide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Biological Activity

Mal-PEG1-acid is a non-cleavable ADC linker containing 1 unit PEG, which can be used to synthesize antibody drug conjugates (ADC),it is a PROTAC linker belonging to the PEG class, which can be used to synthesize PROTAC molecules.

in vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

PEGs

Non-cleavable

Mal-PEG1-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG1-acid Suppliers

Wuhan Brin Technology Co., Ltd.
Tel
3456065315 13260619011
Email
3456065315@qq.com
Country
China
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1752
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Hygeia (Chengdu) pharmaceutical technique Co., Ltd
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028-84502008 13568869383
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sales@hygeiapharm.com
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296
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Jinan elephant international trading co., LTD
Tel
Fax
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13006575422@163.com
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Beijing Jin Ming Biotechnology Co., Ltd.
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psaitong@jm-bio.com
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Amatek Scientific Co. Ltd.
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0512-56316828
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28820
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Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
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China
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Zhengzhou Acme Chemical Co., Ltd.
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0371-037163312495,13303845143 13303845143
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3001379618@qq.com
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Alpha Biopharmaceuticals Co., Ltd
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400-9205774
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Jiangsu aikang biomedical research and development co., LTD
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025-66110311 13155353615
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Labnetwork lnc.
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contact@labnetwork.com
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Nextpeptide Inc
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Hangzhou Huarong Pharm Co., Ltd.
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
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029-86217788 13892832556
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Shanghai Kaiwei Chemical Technology Co., Ltd.
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Changzhou Kechem Bio-Scientific Co., LTD.
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Advanced chemblocks inc
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650-6922368
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Heyuan broad spectrum Biotechnology Co., Ltd
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0762-3393039 18023108599
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Shanghai Haohong Pharmaceutical Co., Ltd.
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400-8210725 4008210725
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Beijing Stronger Science Co., Ltd.
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Shanghai Huici Pharmaceutical Technology Co., LTD
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19372841038 19372841038
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lixing@pharmahuici.com
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216
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Affinity(Wuhan)Ltd.
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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Beijing Solarbio Science & Tecnology Co., Ltd.
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Suzhou Haiben Pharmaceutical Co., Ltd
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Accela ChemBio Co.,Ltd.
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Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
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Baoji Didu Pharmaceutical and Chemical Co., Ltd
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Jilin Chinese Academy of Sciences-yanshen Technology
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Nantong Hanfang Biotechnology Co. , Ltd.
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TargetMol Chemicals Inc.
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Xian confluore Biological Technology Co., Ltd.
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Jilin Chinese Academy of Sciences-yanshen Technology
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View Lastest Price from Mal-PEG1-acid manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Mal-PEG1-acid 760952-64-5
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-27

760952-64-5, Mal-PEG1-acidRelated Search:


  • Mal-PEG1-acid
  • Mal-PEG1-CH2CH2COOH
  • 3-[2-(2,5-Dioxo-2,5-dihydro-1h-pyrrol-1-yl)ethoxy]propanoic acid
  • Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-
  • Mal-PEG1-CH2CH2COOH/Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-
  • 3-[2-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)ethoxy]propanoic Acid
  • 3-[2-(2,5-dioxopyrrol-1-yl)ethoxy]propanoic acid
  • 760952-64-5