ChemicalBook > CAS DataBase List > Mal-PEG6-NHS ester

Mal-PEG6-NHS ester

Product Name: Mal-PEG6-NHS ester
CAS No.: 1599472-25-9
Chemical Name: Mal-PEG6-NHS ester
Synonyms: Mal-PEG6-NHS ester;Mal-PEG6-CH2CH2COONHS;Mal-PEG6-NHS ester ，S0630;2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate;4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber: CB93062545
Molecular Formula: C23H34N2O12
Formula Weight: 530.52
MOL File: 1599472-25-9.mol

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Mal-PEG6-NHS ester Property

Boiling point:: 635.8±65.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Soluble in DCM
pka: -2.34±0.20(Predicted)
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C23H34N2O12/c26-19-1-2-20(27)24(19)6-8-32-10-12-34-14-16-36-18-17-35-15-13-33-11-9-31-7-5-23(30)37-25-21(28)3-4-22(25)29/h1-2H,3-18H2
InChIKey: UUNUCVXNAHYFJP-UHFFFAOYSA-N
SMILES: C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: LIN0000156
Product name: MAL-PEG6-NHS ESTER
Purity: 95.00%
Packaging: 5MG
Price: $499.79
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1507
Product name: Mal-PEG6-NHS ester
Packaging: 100mg
Price: $662
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: LIN0000156
Product name: MAL-PEG6-NHS ESTER
Purity: 95.00%
Packaging: 100MG
Price: $866.25
Updated: 2021/12/16

BroadPharm

Product number: BP-20553
Product name: Mal-PEG6-NHSester
Purity: 98%
Packaging: 1g
Price: $1900
Updated: 2021/12/16

Crysdot

Product number: CD11245135
Product name: 2,5-dioxopyrrolidin-1-yl1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate
Purity: 95+%
Packaging: 1g
Price: $2206
Updated: 2021/12/16

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Mal-PEG6-NHS ester Chemical Properties,Usage,Production

Description

Mal-PEG6-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-PEG6-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester.

IC 50

Non-cleavable Linker

References

[1] Kennett Sprog?e , et al. Relaxin prodrugs. WO2015067791A1.

Mal-PEG6-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Mal-PEG6-NHS ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Mal-PEG6-NHS ester 1599472-25-9
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-27

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2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate

Mal-PEG6-NHS ester

4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester

Mal-PEG6-CH2CH2COONHS

Mal-PEG6-NHS ester ，S0630

1599472-25-9

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