Cilazapril
- Product Name
- Cilazapril
- CAS No.
- 88768-40-5
- Chemical Name
- Cilazapril
- Synonyms
- Vascace;(1S,9S)-;Yipingshu;Ro34-2848;Cilazapril;Ro 31-2848;Ro 34-2848;Ro-34-2848;CILASTATIN NA;Cilazapril USP/EP/BP
- CBNumber
- CB9307140
- Molecular Formula
- C22H31N3O5
- Formula Weight
- 417.5
- MOL File
- 88768-40-5.mol
Cilazapril Property
- Melting point:
- 95-97°C
- Boiling point:
- 598.1±60.0 °C(Predicted)
- Density
- 1.26±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
- form
- powder
- pka
- 2.28±0.20(Predicted)
- color
- White to Off-White
- CAS DataBase Reference
- 88768-40-5(CAS DataBase Reference)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- RTECS
- MJ9650200
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 29777
- Product name
- Cilazapril
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 29777
- Product name
- Cilazapril
- Packaging
- 5mg
- Price
- $78
- Updated
- 2024/03/01
- Product number
- 29777
- Product name
- Cilazapril
- Packaging
- 10mg
- Price
- $122
- Updated
- 2024/03/01
- Product number
- 29777
- Product name
- Cilazapril
- Packaging
- 25mg
- Price
- $267
- Updated
- 2024/03/01
- Product number
- C441200
- Product name
- Cilazapril
- Packaging
- 25mg
- Price
- $290
- Updated
- 2021/12/16
Cilazapril Chemical Properties,Usage,Production
Description
Cilazapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor cilazaprilat. In vivo, cilazapril (0.1 mg/kg) inhibits plasma ACE activity and inhibits the angiotensin I-induced pressor response in anesthetized rats and cats. It decreases systolic blood pressure in spontaneously hypertensive rats when administered at a dose of 30 mg/kg. Cilazapril (10 mg/kg, p.o.) decreases blood pressure in volume-depleted renal hypertensive dogs. Formulations containing cilazapril have been used in the treatment of hypertension.
Chemical Properties
Off-White Solid
Uses
An ACE inhibitor. Hydrolyzed in vivo to the active diacid metabolite (Cilazaprilat). Antihypertensive.
Definition
ChEBI: Cilazapril is a pyridazinodiazepine resulting from the formal condensation of the carboxy group of cilazaprilat with ethanol. It is a drug used in the treatment of hypertension and heart failure. It has a role as a prodrug, an antihypertensive agent and an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. It is an ethyl ester, a pyridazinodiazepine and a dicarboxylic acid monoester. It is functionally related to a Cilazaprilat.
brand name
Inhibace (Hoffmann-LaRoche).
Cilazapril Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Cilazapril manufacturers
- Product
- Cilazapril 88768-40-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Cilazapril 88768-40-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- Cilazapril 88768-40-5
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-09