CILAZAPRIL

Product Name: CILAZAPRIL
CAS No.: 92077-78-6
Chemical Name: CILAZAPRIL
Synonyms: Justor;Dynorm;Vascase;Initiss;Inhibace;Cilazapril CRS;CILAZAPRIL EPC(;Cilazapril Hydrate;Vascace monohydrate;Inhibace monohydrate
CBNumber: CB4771690
Molecular Formula: C22H33N3O6
Formula Weight: 435.51
MOL File: 92077-78-6.mol

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CILAZAPRIL Property

Melting point:: 98° (dec)
alpha: D20 -62.51° (c = 1% in ethanol)
storage temp.: Store at -20°C
solubility: Slightly soluble in water, freely soluble in methanol and in methylene chloride.
pka: pKa1 3.3; pKa2 6.4(at 25℃)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C2174000
Product name: Cilazapril
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: c2174000
Price: $153
Updated: 2024/03/01

Biosynth Carbosynth

Product number: FC34997
Product name: Cilazapril monohydrate
Packaging: 25mg
Price: $185
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC34997
Product name: Cilazapril monohydrate
Packaging: 10mg
Price: $95
Updated: 2021/12/16

ChemScene

Product number: CS-2448
Product name: Cilazaprilmonohydrate
Purity: 99.44%
Packaging: 10mg
Price: $108
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC34997
Product name: Cilazapril monohydrate
Packaging: 5mg
Price: $60
Updated: 2021/12/16

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CILAZAPRIL Chemical Properties,Usage,Production

Description

Cilazapril is a new ACE inhibitor useful in the management of mild to moderate hypertension. Orally administered cilazapril is a prodrug which is de-esterified to its active diacid metabolite cilazprilat. Compared with enalapril and captopril, cilazapril is more potent and longer lasting.

Chemical Properties

White or almost white, crystalline powder.

Originator

Hoffmann-LaRoche (Switzerland)

Uses

Antihypertensive.

Definition

ChEBI: Cilazapril monohydrate is a hydrate that is the monohydrate of cilazapril. It is used for the treatment of hypertension and heart failure. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It contains a cilazapril.

brand name

Inhibace (Hoffmann-LaRoche).

CILAZAPRIL Preparation Products And Raw materials

Raw materials

Lithium tert-butoxide Potassium bicarbonate Diborane Sodium carbonate

Preparation Products

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CILAZAPRIL Suppliers

Canada 2 China 40 France 1 India 4 United Kingdom 1 United States 17 Global 65

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2784
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3868
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27322
Advantage: 60

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Chengdu Dianchun Technology Co., Ltd

Tel: 400-1166-196 18502815961
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14623
Advantage: 60

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29797
Advantage: 68

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View Lastest Price from CILAZAPRIL manufacturers

Dideu Industries Group Limited

Product: CILAZAPRIL 92077-78-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-10

Shaanxi Dideu Medichem Co. Ltd

Product: Cilazapril 92077-78-6
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-09

Career Henan Chemical Co

Product: Cilazapril (monohydrate) 92077-78-6
Price: US $1.00/g
Min. Order: 1g
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-10

92077-78-6, CILAZAPRILRelated Search:

Cefaclor Quinapril hydrochloride Chlorprothixene ENALAPRILAT DIHYDRATE Lopinavir Ramipril Cilazapril

Initiss

Justor

Vascase

9[[1-ETHOXYCARBONYL-3-PHENYLPROPYL]AMINO]OCTAHYDRO-10-OXO-6HPYRIDAZINO[1,2-A][1,2]DIAZEPINE-1-CARBOXYLIC ACID

CILAZAPRIL EPC(

CILAZAPRIL EPC(CRM STANDARD)

CILAZAPRIL IMPURITY A1,1-DIMETHYLETHYL(1S,9S)-9-[[(S)-1-ETHOXYCARBONYL-3-PHENYLPROPYL]AMINO]-10-OXO-OCTAHYDRO-6H-PYRIDAZINO[1,2A][1,2]DIAZEPINE-1-CABOXYLATE EPC

[1S-[1α，9α(R^<*>^)]]-9-[[1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1，2-α][1，2]diazepine-1-carboxylic acid monohydrate

9-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-10-oxo-1,2,3,4,6,7,8,9-oc tahydropyridazino[1,2-a]diazepine-1-carboxylic acid

Inhibace

Cilazapril Hydrate

Inhibace monohydrate

INHIBACE MONOHYDRATE;RO 31-2848 MONOHYDRATE;VASCACE MONOHYDRATE

Vascace monohydrate

(1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]aMino}-1-hydroxy-10-oxo-octahydro-1H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid

Cilazapril Monohydrate (Inhibace)

6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylicacid, 9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]aMino]octahydro-10-oxo-,hydrate (1:1), (1S,9S)-

(1S,9S)-9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, hydrate (1:1)

(1S,9S)-9-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid hydrate

(1S,9S)-9-{[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid hydrate (1:1)

6h-pyridazino(1,2-a)(1,2)diazepine-1-carboxylicacid,octahydro-9-((1-(ethoxyca

cilazaprilmonohydrate

hydrate,(1s-(1-alpha,9-alpha(r*)))-rbonyl)-3-phenylpropyl)amino)-10-oxo

ro31-2848monohydrate

(1s,9s)-9-[(s)-1-ethoxycarbonyl-3-phenylpropylamino]-10-oxoperhydropyridazino[1,2-a][1,2]diazepine-1-carboxylic acid

Cilazapril CRS

(1S,9S)-9-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-10-oxooctahydro-1H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid

Cilazapril Monohydrate (Ro 31-2848)

(1S,9S)-9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-10-oxooctahydro-6h-pyridazino[1,2-a][1,2]diazepine-1-carboxylicacidmonohydrate

Dynorm

92077-78-6

C22H31N3O5H2O

Inhibitors