ChemicalBook > CAS DataBase List > 1-Methyl-1H-pyrazole-4-carbaldehyde

1-Methyl-1H-pyrazole-4-carbaldehyde

Product Name
1-Methyl-1H-pyrazole-4-carbaldehyde
CAS No.
25016-11-9
Chemical Name
1-Methyl-1H-pyrazole-4-carbaldehyde
Synonyms
1-METHYL-1H-PYRAZOLE-4-CARBOXALDEHYDE;Pyrazole-4-carboxaldehyde, 1-methyl-;1-Methylpyrazole-4-carbaldehyde;AKOS B000400;AKOS PAO-0259;CHEMBRDG-BB 4301129;IFLAB-BB F2124-0695;TIMTEC-BB SBB000002;ART-CHEM-BB B000400;ASINEX-REAG BAS 00468061
CBNumber
CB9307807
Molecular Formula
C5H6N2O
Formula Weight
110.11
MOL File
25016-11-9.mol
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1-Methyl-1H-pyrazole-4-carbaldehyde Property

Melting point:
29-34 °C
Boiling point:
60-62°C/0.08mm
Density 
1.14±0.1 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
pka
0.17±0.10(Predicted)
form 
powder to lump to clear liquid
color 
White or Colorless to Yellow to Orange
Sensitive 
Air Sensitive
InChI
InChI=1S/C5H6N2O/c1-7-3-5(4-8)2-6-7/h2-4H,1H3
InChIKey
MYFZXSOYJVWTBL-UHFFFAOYSA-N
SMILES
N1(C)C=C(C=O)C=N1
CAS DataBase Reference
25016-11-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41-43
Safety Statements 
26-36/37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29331990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
654043
Product name
1-Methyl-1H-pyrazole-4-carboxaldehyde
Purity
96%
Packaging
1g
Price
$39.8
Updated
2023/06/20
TCI Chemical
Product number
M2372
Product name
1-Methylpyrazole-4-carboxaldehyde
Purity
>98.0%(GC)
Packaging
1g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
M2372
Product name
1-Methylpyrazole-4-carboxaldehyde
Purity
>98.0%(GC)
Packaging
5g
Price
$73
Updated
2024/03/01
Alfa Aesar
Product number
H54146
Product name
1-Methyl-1H-pyrazole-4-carboxaldehyde, 96%
Packaging
1g
Price
$68.65
Updated
2024/03/01
TRC
Product number
M330333
Product name
1-Methyl-1H-pyrazole-4-carbaldehyde
Packaging
100mg
Price
$75
Updated
2021/12/16
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1-Methyl-1H-pyrazole-4-carbaldehyde Chemical Properties,Usage,Production

Uses

1-Methyl-1H-pyrazole-4-carbaldehyde is a pharmaceutical intermediate used in the synthesis of the CHK1 inhibitor MK-8776.

Synthesis

Using cyclopropyl methyl ketone and dimethoxy-N, N-dimethylmethylamine as starting materials, the target product 1-Methyl-1H-pyrazole-4-carbaldehyde was obtained through aldol condensation, hydrazine condensation cyclization, selective methylation reaction and Vilsmeier-Hack reaction in sequence, with a total yield of up to 48.0%.

1-Methyl-1H-pyrazole-4-carbaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Methyl-1H-pyrazole-4-carbaldehyde Suppliers

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View Lastest Price from 1-Methyl-1H-pyrazole-4-carbaldehyde manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
1-Methyl-1H-pyrazole-4-carbaldehyde 25016-11-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-Methyl-1H-pyrazole-4-carbaldehyde 25016-11-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-Methyl-1H-pyrazole-4-carboxaldehyde 25016-11-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

25016-11-9, 1-Methyl-1H-pyrazole-4-carbaldehydeRelated Search:


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