2-Amino-6-chloro-4-nitrophenol

Product Name: 2-Amino-6-chloro-4-nitrophenol
CAS No.: 6358-09-4
Chemical Name: 2-Amino-6-chloro-4-nitrophenol
Synonyms: 1628499;TIMTEC-BB SBB007546;2-Amino-4-nitro-6-chloro;-Amino-6-Chloro-4-Nitrophenol;2-AMIO-6-CHLORO-4-NITROPHENOL;4-Nitro-6-chloro-2-aminophenol;6-CHLORO-2-AMINO-4-NITROPHENOL;2-amino-6-chloro-4-nitro-pheno;2-AMINO-6-CHLORO-4-NITROPHENOL;2-amino-6-chloro-p-nitrophenol
CBNumber: CB9312623
Molecular Formula: C6H5ClN2O3
Formula Weight: 188.57
MOL File: 6358-09-4.mol

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2-Amino-6-chloro-4-nitrophenol Property

Melting point:: 158-162.5℃
Boiling point:: 358.7±42.0 °C(Predicted)
Density: 1.655±0.06 g/cm3(Predicted)
vapor pressure: 0.002Pa at 32℃
RTECS: ST5743000
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 5.20±0.44(Predicted)
form: Powder
color: Orange
Water Solubility: 450mg/L at 25℃
Cosmetics Ingredients Functions: HAIR DYEING
Cosmetic Ingredient Review (CIR): 2-Amino-6-chloro-4-nitrophenol (6358-09-4)
InChI: InChI=1S/C6H5ClN2O3/c7-4-1-3(9(11)12)2-5(8)6(4)10/h1-2,10H,8H2
InChIKey: TWLMSPNQBKSXOP-UHFFFAOYSA-N
SMILES: C1(O)=C(Cl)C=C([N+]([O-])=O)C=C1N
LogP: 1.8 at 20℃
CAS DataBase Reference: 6358-09-4(CAS DataBase Reference)
EPA Substance Registry System: Phenol, 2-amino-6-chloro-4-nitro- (6358-09-4)

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Safety

Hazard Codes: Xi
Hazard Note: Irritant
TSCA: TSCA listed
HazardClass: 6.1
HS Code: 29225090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2245
Product name: 2-Amino-6-chloro-4-nitrophenol
Purity: >98.0%(T)
Packaging: 5g
Price: $91
Updated: 2025/07/31

TCI Chemical

Product number: A2245
Product name: 2-Amino-6-chloro-4-nitrophenol
Purity: >98.0%(T)
Packaging: 25g
Price: $312
Updated: 2025/07/31

TRC

Product number: A604073
Product name: 2-Amino-6-chloro-4-nitrophenol
Packaging: 500mg
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: I642
Product name: 2-Amino-4-nitro-6-chlorophenol
Packaging: 1g
Price: $14
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA50776
Product name: 2-Amino-6-chloro-4-nitrophenol
Packaging: 2g
Price: $40
Updated: 2021/12/16

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2-Amino-6-chloro-4-nitrophenol Chemical Properties,Usage,Production

Chemical Properties

Dull yellow to brown powder

Uses

2-Amino-6-chloro-4-nitrophenol has cosmetic application in hair dye compositions.

Flammability and Explosibility

Not classified

Synthesis

To the 500ml reaction flask add 2-amino-4-nitrophenol 30.8g (0.2mol), 150g of ethylene dichloride, and 0.5g of iodine-containing ferric chloride, stirring, lower the temperature to 15 ??, began to drop 29.7g (0.22mol) sulfuryl chloride, the reaction is slightly exothermic, control the droplet temperature below 20 ??, droplet after the end of the heat preservation of 1.0 hours, and then slowly increase the temperature to 35 ??, hold 2 hours, sampling control to raw materials less than 0.5%, the end of the reaction, distillation under pressure to recover dichloroethane, the first recovery of 70% of the solvent (by volume), and then make up 200g of deionized water, and continue to steam the solvent, to be fully recovered dichloroethane, drop 30% of the liquid alkali to the reaction solution pH to 8.5, the temperature rose to 80 ??, the material is completely soluble, add 3g of activated carbon, hold 1.0 hours. After the material is completely dissolved, add 3g of activated carbon, keep warm for 1.0 hours, filter while hot, the filtrate is cooled down to 30??, start to add hydrochloric acid dropwise, adjust the pH to 4.5, keep warm for 0.5h, filter, get 50g of yellowish-green color tide, dry at 70?? for 18 hours, get reddish-brown solid 2-amino-6-chloro-4-nitrophenol 30.2g, the yield is 80.0%, HPLC: 99.5%.

2-Amino-6-chloro-4-nitrophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-6-chloro-4-nitrophenol Suppliers

Americas 1 China 175 Europe 3 Germany 1 India 9 Japan 3 Russia 1 The Netherlands 1 United Kingdom 10 United States 20 Global 224

Changsha Changtang Import and Export Co., LTD

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View Lastest Price from 2-Amino-6-chloro-4-nitrophenol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2-Amino-6-chloro-4-nitrophenol 6358-09-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-24

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2-Amino-6-chloro-4-nitrophenol 9358-09-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-24

Baoji Guokang Healthchem Co., Ltd.

Product: 2-Amino-6-chloro-4-nitrophenol 6358-09-4
Price: US $40.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1 ton
Release date: 2021-06-08

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C6H5ClN2O3

Intermediates of Dyes and Pigments