Aprepitant Impurity 6

Product Name: Aprepitant Impurity 6
CAS No.: 170902-81-5
Chemical Name: Aprepitant Impurity 6
Synonyms: 1S, 2R, 3S-Aripitan;Aprepitant Impurity 5(S,R,S-Isomer);Fosaprepitant Dimeglumine Impurity A;Arepitam impurity isomers (1S, 2R, 3S);Fosaprepitant Dimeglumine EP Impurity A;Aprepitant impurity 9/(1S,2R,3S)-Aprepitant;[1(S)-Phenylethoxy]-Aprepitant/ Aprepitant S,R,S-Isomer;5-([(2R,3S)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one;5-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
CBNumber: CB93146511
Molecular Formula: C23H21F7N4O3
Formula Weight: 534.43
MOL File: 170902-81-5.mol

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Aprepitant Impurity 6 Property

Density: 1.51±0.1 g/cm3(Predicted)
pka: 8.06±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: P320780
Product name: [1(S)-Phenylethoxy]-Aprepitant
Packaging: 1mg
Price: $125
Updated: 2021/12/16

TRC

Product number: P320780
Product name: [1(S)-Phenylethoxy]-Aprepitant
Packaging: 10mg
Price: $1010
Updated: 2021/12/16

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Aprepitant Impurity 6 Chemical Properties,Usage,Production

Uses

[1(S)-Phenylethoxy]-Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.

Aprepitant Impurity 6 Preparation Products And Raw materials

Raw materials

Preparation Products

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Aprepitant Impurity 6 Suppliers

China 30 India 3 United States 4 Global 37

170902-81-5, Aprepitant Impurity 6Related Search:

(2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine Aprepitant (2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Aprepitant Benzyl dihydrogen phosphate Fosaprepitant Benzyl Ester Defluoro Aprepitant Aprepitant (2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride 4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE Aprepitant Impurity A Enantiomer Aprepitant Fosaprepitant Impurity 6 ent-Aprepitant 5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one Aprepitant Impurity 11 HCl Aprepitant Impurity 2

Fosaprepitant Dimeglumine Impurity A

Aprepitant Impurity 5(S,R,S-Isomer)

Aprepitant impurity 9/(1S,2R,3S)-Aprepitant

1S, 2R, 3S-Aripitan

Arepitam impurity isomers (1S, 2R, 3S)

5-([(2R,3S)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one

3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-

Fosaprepitant Dimeglumine EP Impurity A

5-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

[1(S)-Phenylethoxy]-Aprepitant/ Aprepitant S,R,S-Isomer

170902-81-5