(2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE

Product Name: (2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE
CAS No.: 287930-75-0
Chemical Name: (2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE
Synonyms: C21H1gF6NO3;Fosartan impurity;(R)-2-((R)-1-(3,5-bi;Aprepitant iMpurity 39;Aprepitant Impurity 29;Fosaprepitant Impurity C;(2R)-4-Benzyl-2-{(1R)-1-[3,5-Bis(trifluoromethyl);3-Morpholinone,2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]eth...;4-benzyl-2-[1-[3, 5-bis (trifluoromethyl)phenyl]ethoxy]morpholin-3-one;(R)-4-benzyl-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)Morpholin-3-one
CBNumber: CB31479172
Molecular Formula: C21H19F6NO3
Formula Weight: 447.37
MOL File: 287930-75-0.mol

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(2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE Property

Boiling point:: 457.4±45.0 °C(Predicted)
Density: 1.37
storage temp.: 2-8°C
pka: -2.18±0.40(Predicted)
InChI: InChI=1S/C21H19F6NO3/c1-13(15-9-16(20(22,23)24)11-17(10-15)21(25,26)27)31-19-18(29)28(7-8-30-19)12-14-5-3-2-4-6-14/h2-6,9-11,13,19H,7-8,12H2,1H3/t13-,19-/m1/s1
InChIKey: KVPJNHLVRGUYGQ-BFUOFWGJSA-N
SMILES: N1(CC2=CC=CC=C2)CCO[C@H](O[C@@H](C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C)C1=O

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B657180
Product name: (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone
Packaging: 25mg
Price: $165
Updated: 2021/12/16

TRC

Product number: B657180
Product name: (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone
Packaging: 250mg
Price: $1320
Updated: 2021/12/16

Matrix Scientific

Product number: 091905
Product name: (R)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)-phenyl)ethoxy)morpholin-3-one
Purity: 95+%
Packaging: 1g
Price: $85
Updated: 2021/12/16

AK Scientific

Product number: Y0383
Product name: (R)-4-benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)morpholin-3-one
Packaging: 1g
Price: $164
Updated: 2021/12/16

Matrix Scientific

Product number: 091905
Product name: (R)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)-phenyl)ethoxy)morpholin-3-one
Purity: 95+%
Packaging: 5g
Price: $265
Updated: 2021/12/16

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(2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE Chemical Properties,Usage,Production

Uses

(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone, is the key 3-(4-Fluorophenyl)morpholine moiety used in the synthesis of NK1 receptor antagonist Aprepitant (A729800).

(2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE Suppliers

China 143 India 3 United States 7 Global 153

Enantiotech Corporation Ltd

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View Lastest Price from (2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: (2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE 287930-75-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-09

Hangzhou ICH Biofarm Co., Ltd

Product: (2R)-4-benzyl-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]morpholin-3-one 287930-75-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200
Release date: 2023-07-18

Career Henan Chemical Co

Product: (2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE 287930-75-0
Price: US $100.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-07-26

287930-75-0, (2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONERelated Search:

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine TRANS-4-AMINOCROTONIC ACID 7-Fluoro-4-quinazolone 7-Fluoro-6-nitro-4-hydroxyquinazoline Afatinib impurity 45 Benzyl dihydrogen phosphate (2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine (2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Aprepitant (2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Aprepitant Impurity 17 Aprepitant Impurity 6 Aprepitant Fosaprepitant Benzyl Ester (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate

(2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE

(R)-4-benzyl-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)Morpholin-3-one

(2R)-4-Benzyl-2-{(1R)-1-[3,5-Bis(trifluoromethyl)

Aprepitant Impurity 29

Aprepitant iMpurity 39

(R)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one

(2R)-4-benzyl-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)Morpholin-3-one

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-4-(phenylMethyl)-3-Morpholinone

3-Morpholinone,2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-4-(phenylMethyl)-, (2R)-

4-benzyl-2-[1-[3, 5-bis (trifluoromethyl)phenyl]ethoxy]morpholin-3-one

(R)-2-((R)-1-(3,5-bi

Fosaprepitant Impurity C

Fosartan impurity

3-Morpholinone,2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]eth...

C21H1gF6NO3

(2R,2-alpha-R)-4-Benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1,4-oxazin-3-one

(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]-ethoxy]-4-(benzyl)morpholin-3-one

287930-75-0

C21H19F6NO3