(1S,2R,3R)-Aprepitant

Product Name: (1S,2R,3R)-Aprepitant
CAS No.: 1242175-34-3
Chemical Name: (1S,2R,3R)-Aprepitant
Synonyms: Aprepitant Impurity 7;Aprepitant impurity 05;Aprepitant iMpurity 31;(2R,3R,1’S)-Aprepitant;Aprepitant (S,R,R)-Isomer;Aprepitant Impurity 4(S,R,R-Isomer);Aprepitant impurity 8/(1S,2R,3R)-Aprepitant;5-([(2R,3R)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one;5-[[(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one;3H-1,2,4-Triazol-3-one, 5-[[(2R,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
CBNumber: CB83146509
Molecular Formula: C23H21F7N4O3
Formula Weight: 534.43
MOL File: 1242175-34-3.mol

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(1S,2R,3R)-Aprepitant Property

Density: 1.51±0.1 g/cm3(Predicted)
pka: 8.06±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A729765
Product name: (2R,3R,1’S)-Aprepitant
Packaging: 1mg
Price: $130
Updated: 2021/12/16

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(1S,2R,3R)-Aprepitant Chemical Properties,Usage,Production

Uses

(2R,3R,1’S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(1S,2R,3R)-Aprepitant Preparation Products And Raw materials

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(1S,2R,3R)-Aprepitant Suppliers

China 31 India 3 United States 4 Global 38

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View Lastest Price from (1S,2R,3R)-Aprepitant manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Aprepitant Impurity 31 1242175-34-3
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 98%
Supply Ability: 500mg
Release date: 2024-06-11

1242175-34-3, (1S,2R,3R)-AprepitantRelated Search:

(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one (2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE Aprepitant Fosaprepitant dimeglumine (R,R,R)-Aprepitant 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one Fosaprepitant Impurity 6 1,1,1-Trimethoxy-2-chloroethane Fosaprepitant Impurity 5 Fosaprepitant (2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine Aprepitant Impurity 9 Aprepitant Defluoro Aprepitant Aprepitant Impurity B HCl 5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one Aprepitant Impurity 11 HCl Aprepitant Impurity 2

Aprepitant Impurity 7

5-[[(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one

Aprepitant (S,R,R)-Isomer

(2R,3R,1’S)-Aprepitant

Aprepitant iMpurity 31

Aprepitant Impurity 4(S,R,R-Isomer)

Aprepitant impurity 8/(1S,2R,3R)-Aprepitant

5-([(2R,3R)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one

3H-1,2,4-Triazol-3-one, 5-[[(2R,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-

Aprepitant impurity 05

1242175-34-3