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(1S,2R,3R)-Aprepitant

Product Name
(1S,2R,3R)-Aprepitant
CAS No.
1242175-34-3
Chemical Name
(1S,2R,3R)-Aprepitant
Synonyms
Aprepitant Impurity 7;Aprepitant impurity 05;Aprepitant iMpurity 31;(2R,3R,1’S)-Aprepitant;Aprepitant (S,R,R)-Isomer;Aprepitant Impurity 4(S,R,R-Isomer);Aprepitant impurity 8/(1S,2R,3R)-Aprepitant;5-([(2R,3R)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one;5-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;5-[[(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one
CBNumber
CB83146509
Molecular Formula
C23H21F7N4O3
Formula Weight
534.43
MOL File
1242175-34-3.mol
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(1S,2R,3R)-Aprepitant Property

Density 
1.51±0.1 g/cm3(Predicted)
pka
8.06±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A729765
Product name
(2R,3R,1’S)-Aprepitant
Packaging
1mg
Price
$130
Updated
2021/12/16
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(1S,2R,3R)-Aprepitant Chemical Properties,Usage,Production

Uses

(2R,3R,1’S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(1S,2R,3R)-Aprepitant Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (1S,2R,3R)-Aprepitant manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Aprepitant Impurity 31 1242175-34-3
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98%
Supply Ability
500mg
Release date
2024-06-11

1242175-34-3, (1S,2R,3R)-AprepitantRelated Search:


  • Aprepitant Impurity 7
  • 5-[[(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one
  • Aprepitant (S,R,R)-Isomer
  • (2R,3R,1’S)-Aprepitant
  • Aprepitant iMpurity 31
  • Aprepitant Impurity 4(S,R,R-Isomer)
  • Aprepitant impurity 8/(1S,2R,3R)-Aprepitant
  • 5-([(2R,3R)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one
  • 3H-1,2,4-Triazol-3-one, 5-[[(2R,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
  • Aprepitant impurity 05
  • 5-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
  • 1242175-34-3