ChemicalBook > CAS DataBase List > (1S,2R,3R)-Aprepitant
(1S,2R,3R)-Aprepitant
- Product Name
- (1S,2R,3R)-Aprepitant
- CAS No.
- 1242175-34-3
- Chemical Name
- (1S,2R,3R)-Aprepitant
- Synonyms
- Aprepitant Impurity 7;Aprepitant impurity 05;Aprepitant iMpurity 31;(2R,3R,1’S)-Aprepitant;Aprepitant (S,R,R)-Isomer;Aprepitant Impurity 4(S,R,R-Isomer);Aprepitant impurity 8/(1S,2R,3R)-Aprepitant;5-([(2R,3R)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one;5-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;5-[[(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one
- CBNumber
- CB83146509
- Molecular Formula
- C23H21F7N4O3
- Formula Weight
- 534.43
- MOL File
- 1242175-34-3.mol
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(1S,2R,3R)-Aprepitant Property
- Density
- 1.51±0.1 g/cm3(Predicted)
- pka
- 8.06±0.20(Predicted)
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N-Bromosuccinimide Price
TRC
- Product number
- A729765
- Product name
- (2R,3R,1’S)-Aprepitant
- Packaging
- 1mg
- Price
- $130
- Updated
- 2021/12/16
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(1S,2R,3R)-Aprepitant Chemical Properties,Usage,Production
Uses
(2R,3R,1’S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.
(1S,2R,3R)-Aprepitant Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (1S,2R,3R)-Aprepitant manufacturers
ShenZhen H&D Pharmaceutical Technology Co., LTD
- Product
- Aprepitant Impurity 31 1242175-34-3
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 98%
- Supply Ability
- 500mg
- Release date
- 2024-06-11
1242175-34-3, (1S,2R,3R)-AprepitantRelated Search:
(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one
(2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE
Aprepitant
Fosaprepitant dimeglumine
(R,R,R)-Aprepitant
5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one
Fosaprepitant Impurity 6
1,1,1-Trimethoxy-2-chloroethane
Fosaprepitant Impurity 5
Fosaprepitant
(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine
Aprepitant Impurity 9
Aprepitant
Defluoro Aprepitant
Aprepitant Impurity B HCl
5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
Aprepitant Impurity 11 HCl
Aprepitant Impurity 2