ChemicalBook > CAS DataBase List > (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride

Product Name
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride
CAS No.
171482-05-6
Chemical Name
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride
Synonyms
Aprepitant HCl;Aprepitant intermediate;APREPITANT INTERMEDIATES;Aprepitant M2 Matabolite;(2R,3S)-2-((R)-1-(3,5-Bi;Aprepitant Impurity 19 HCl;Aprepitant Stage-II (Impurity-A);Aprepitant Impurity 1 Enantiomer HCl;Aprepitant M2 Metabolite (1R, 2R, 3S);(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy
CBNumber
CB51473341
Molecular Formula
C20H19ClF7NO2
Formula Weight
473.82
MOL File
171482-05-6.mol
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(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride Property

storage temp. 
Inert atmosphere,Room Temperature
form 
solid
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Hazard and Precautionary Statements (GHS)

Signal word
Danger
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N-Bromosuccinimide Price

Matrix Scientific
Product number
091946
Product name
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)-ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride
Purity
95+%
Packaging
1g
Price
$85
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0005691
Product name
APREPITANT-M2 HYDROCHLORIDE
Purity
95.00%
Packaging
1G
Price
$224.7
Updated
2021/12/16
Matrix Scientific
Product number
091946
Product name
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)-ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride
Purity
95+%
Packaging
5g
Price
$320
Updated
2021/12/16
AK Scientific
Product number
Y0384
Product name
(2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholinehydrochloride
Packaging
5g
Price
$253
Updated
2021/12/16
Chemenu
Product number
CM163754
Product name
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)-ethoxy)-3-(4-fluorophenyl)morpholinehydrochloride
Purity
95%
Packaging
10g
Price
$262
Updated
2021/12/16
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(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride Chemical Properties,Usage,Production

Uses

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride is an important pharmaceutical intermediate compound whose reaction unit is used in the synthesis of aprepitant intermediates. Arepitane is a neurokinin-1 antagonist analogue. It is used for the management and prevention of chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV) in cancer patients.

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride Suppliers

Nanjing Gold Pharmaceutical Technology Co. Ltd.
Tel
025-84209270; 15905158493
Fax
025-84209270
Email
wgp@nanjing-pharmaceutical.com
Country
China
ProdList
69
Advantage
55
Enantiotech Corporation Ltd
Tel
760-85282375 13212762451
Email
marketing@enantiotech.net
Country
China
ProdList
179
Advantage
55
Viwit Pharmaceutical Co., Ltd.
Tel
0632-2980981 15063270987
Fax
0632-2989678
Email
service.china3@viwit.com
Country
China
ProdList
116
Advantage
55
Zhejiang Warrant Pharmaceutical Co.,Ltd.
Tel
0512-85180611 17312581805
Fax
0512-89171181
Email
felix@lanxite.com
Country
China
ProdList
6
Advantage
55
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2923
Advantage
55
Chemvon Biotechnology Co., Ltd
Tel
021-50790412
Fax
+86-21-50790419
Email
info@chemvon.com
Country
China
ProdList
371
Advantage
57
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7639
Advantage
55
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
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View Lastest Price from (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride manufacturers

Hangzhou ICH Biofarm Co., Ltd
Product
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine hydrochloride 171482-05-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
≥1kg
Release date
2023-07-18
Anhui Ruihan Technology Co., Ltd
Product
(2R,3S)-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}-3-(4-FLUOROPHENYL)MORPHOLINE HYDROCHLORIDE 171482-05-6
Price
US $80.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000tons
Release date
2023-09-11
Hebei Lihe Biotechnology Co.,Ltd
Product
(2R,3S)-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}-3-(4-FLUOROPHENYL)MORPHOLINE HYDROCHLORIDE 171482-05-6
Price
US $37.00/KG/Tin
Min. Order
10g
Purity
99%
Supply Ability
10tons
Release date
2020-10-27

171482-05-6, (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochlorideRelated Search:


  • (2R,3S)-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}-3-(4-FLUOROPHENYL)MORPHOLINE HYDROCHLORIDE
  • (2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride (1:1)
  • Aprepitant HCl
  • APREPITANT INTERMEDIATES
  • Aprepitant M2 Metabolite (1R, 2R, 3S)
  • (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)-ethoxy)-3-(4-fluorophenyl)morpholine hydrochlor
  • (2R,3S)-2-((R)-1-(3,5-Bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine hydrochloride
  • (2R, 3S)-2-(1R)-1-(3, 5-BIS (TRIFLUOROMETHYL)-3-(4-FLUOROPHENYL) MORPHOLINE HYDROCHLORIDE
  • Aprepitant M2 Matabolite
  • Aprepitant Stage-II (Impurity-A)
  • Aprepitant intermediate
  • 2R 3S)-2-(1R)-1-3,5-Bis(Trifluoromethyl)Phenyl)Ethoxy)-3-(4Fluoropheny)Morpholine Hydrochloride
  • Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, hydrochloride (1:1), (2R,3S)-
  • Aprepitant int-3 (2R,3S)-2-((R)-1-(3,5-Bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine hydrochloride
  • (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)-ethoxy)-3-(4-fluorophenyl)morpholine hydroch
  • Aprepitant Impurity 1 Enantiomer HCl
  • (2R,3S)-2-((R)-1-(3,5-Bi
  • Morpholine,2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-,hydrochloride, (2R,3S)-
  • (2R,3S)-2-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-...
  • (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl) morpholine hydrochlorid
  • (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy
  • Aprepitant Impurity 19 HCl
  • (2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl) phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride [APT07]
  • 171482-05-6
  • C20H18F7NO2HCl
  • C20H19ClF7NO2
  • C20H18F7NO2ClH
  • 171482-05-6