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Anhydrosafflor yellow B

Product Name
Anhydrosafflor yellow B
CAS No.
184840-84-4
Chemical Name
Anhydrosafflor yellow B
Synonyms
AHSYB;Anhydrosafflor yellow B;(2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1;4(2H)-Benzofuranone, 7-β-D-glucopyranosyl-3-[3-β-D-glucopyranosyl-2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-6-oxo-1,4-cyclohexadien-1-yl]-3,7-dihydro-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-, (2S,3S)-
CBNumber
CB93313458
Molecular Formula
C48H52O26
Formula Weight
1044.92
MOL File
184840-84-4.mol
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Anhydrosafflor yellow B Property

Boiling point:
1462.3±65.0 °C(Predicted)
Density 
1.88±0.1 g/cm3(Predicted)
pka
4.50±1.00(Predicted)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0032088
Product name
AnhydrosaffloryellowB
Packaging
1mg
Price
$255
Updated
2021/12/16
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Anhydrosafflor yellow B Chemical Properties,Usage,Production

Description

Safflower, also known as red and blue flower, thorn safflower, mainly contains compounds such as chalcone pigments, flavonoids, phenolic acids, steroids and polysaccharides. Among the safflower yellows, hydroxyl safflower yellow A and dehydrated safflower yellow B (AHSYB) have the highest content, which are the main active ingredients with physiological activity in safflower.Anhydrosafflor yellow B can improve heart and brain blood oxygen supply, reduce ischemic injury, anticoagulant, anti-myocardial ischemia, inhibit platelet aggregation, anti-oxidation, anti-tumor and anti-inflammation and other pharmacological effects.

Uses

Anhydrosafflor yellow B (AHSYB) is a quinochalcone C-glycoside isolated from Carthamus tinctorius. Anhydrosafflor yellow B inhibits ADP-induced platelet aggregation, exhibits significant anti-oxidative effects in vitro, and possesses certain activity against H2O2-induced cytotoxicity in cultured PC12 cells and primary neuronal cells[1].

Biological Activity

Anhydrosafflor yellow B (AHSYB) is a quinolone C-glycoside isolated from Carthamus tinctorius. It inhibits ADP-induced platelet aggregation, has significant antioxidant effects in vitro, and has antitoxic activity against H2O2-induced PC12 cells and primary neuronal cells.

Synthesis

A method for extracting and purifying dehydrated safflower yellow B in safflower, 1) using warm soaking method to obtain safflower water extract; 2) pretreatment of macroporous adsorption resin; 3) macroporous resin adsorption; 4) macroporous resin Pore resin elution.

References

[1] Yue S, et al. Metabolic profile of anhydrosafflor yellow B in rats by ultra-fast liquid chromatography/quadrupole time-of-flight mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2016;1014:37-44. DOI:10.1016/j.jchromb.2016.01.047

Anhydrosafflor yellow B Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Anhydrosafflor yellow B manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Anhydrosafflor yellow B 184840-84-4
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-04-16

184840-84-4, Anhydrosafflor yellow BRelated Search:


  • Anhydrosafflor yellow B
  • 4(2H)-Benzofuranone, 7-β-D-glucopyranosyl-3-[3-β-D-glucopyranosyl-2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-6-oxo-1,4-cyclohexadien-1-yl]-3,7-dihydro-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-, (2S,3S)-
  • (2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1
  • AHSYB
  • 184840-84-4
  • C48H52O26