Clinofibrate

Product Name: Clinofibrate
CAS No.: 30299-08-2
Chemical Name: Clinofibrate
Synonyms: S 8527;lipoclin;bis(oxy);CLINOFIBRATE;Clinofibrate >CLINOFIBRATE (S-8527);Clinofibrate USP/EP/BP;2,2'-(cyclohexyliden...;CLINOFIBRATE(FORR&DONLY);bis(2-methylbutanoic acid)
CBNumber: CB9333525
Molecular Formula: C28H36O6
Formula Weight: 468.58
MOL File: 30299-08-2.mol

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Clinofibrate Property

Melting point:: 143-145°C
Boiling point:: 498.6°C (rough estimate)
Density: 1.1005 (rough estimate)
refractive index: 1.4482 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Sligthly)
form: Solid
pka: 3.00±0.10(Predicted)
color: White to Off-White
Merck: 14,2357
CAS DataBase Reference: 30299-08-2(CAS DataBase Reference)

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Safety

RTECS: ES8900000
HS Code: 2918.99.4700

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical

Product number: C3100
Product name: Clinofibrate
Purity: >98.0%(HPLC)
Packaging: 200mg
Price: $93
Updated: 2024/03/01

TCI Chemical

Product number: C3100
Product name: Clinofibrate
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $282
Updated: 2024/03/01

TRC

Product number: C580100
Product name: Clinofibrate
Packaging: 5mg
Price: $50
Updated: 2021/12/16

TRC

Product number: C580100
Product name: Clinofibrate
Packaging: 100mg
Price: $590
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC20487
Product name: Clinofibrate
Packaging: 50mg
Price: $841.5
Updated: 2021/12/16

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Clinofibrate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Lipocrin,Sumitomo,Japan,1981

Uses

Clinofibrate is an antilipemic, used as an anti-atherosclerosis agent.

Definition

ChEBI: Clinofibrate is an organic molecular entity.

Manufacturing Process

Into a mixture of 6.0 g of a bishydroxyphenyl derivative, and 44.0 g of methyl ethyl ketone was added 16.2 g of crushed potassium hydroxide or sodium hydroxide. Chloroform was added dropwise into the above mixture with stirring at 20°C to 80°C, and the resultant mixture was heated for 20 hours under reflux to complete the reaction. Thereafter the reaction mixture was concentrated to give a residue. Into the residue was added water. After cooling, the resultant mixture was treated with activated charcoal and acidified by diluted hydrochloric acid or sulfuric acid to give an oily substance. The oily substance was extracted by ether and the ether solution was contacted with aqueous diluted Na2CO3 solution. The separated aqueous layer was washed with ether, acidified and again extracted with ether. The obtained ester layer was dried over anhydrous sodium sulfate and concentrated to give 1.0 g of a crude product which was purified by recrystallization or chromatography, to give crystals MP 143°C to 146°C (decomp.)

Therapeutic Function

Antihyperlipoproteinemic

Clinofibrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Clinofibrate Suppliers

Americas 1 Canada 1 China 126 Europe 1 Germany 1 India 2 Japan 1 United Kingdom 5 United States 23 Global 161

Pure Chemistry Scientific Inc.

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Target molecule Corp.

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ChemPacific Corporation

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View Lastest Price from Clinofibrate manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Clinofibrate 30299-08-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-11

Career Henan Chemical Co

Product: Clinofibrate 30299-08-2
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KG
Release date: 2019-08-31

30299-08-2, ClinofibrateRelated Search:

Paraquat dichloride Methyl acetate Basic Violet 1 Butyric Acid Methanol Acetonitrile Methyl acrylate Methylparaben Bezafibrate Kresoxim-methyl lifibrate Methyl 4,4'-Cyclohexylidenebisphenol 4-TERT-BUTYLPHENOXYACETIC ACID 4,4'-ISOPROPYLIDENEBIS(2-PHENOXYETHANOL) 2-Phenoxybutyric acid (S)-(+)-2-Methylbutyric acid Methylbutyric acid

CLINOFIBRATE (S-8527)

2,2’-cyclohexane-1,1-diylbis(p-phenyleneoxy)bis(2-methylbutyricacid)

lipoclin

2,2'-(cyclohexylidenebis(4,1-phenyleneoxy))bis(2-methyl)-butanoic acid

CLINOFIBRATE

CLINOFIBRATE(FORR&DONLY)

1,1-Bis[4'-(1''-carboxy-1''-methylpropoxy)phenyl]cyclohexane

Butanoic acid, 2,2'-[cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methyl-

S 8527

2,2'-[(1,1-Cyclohexanediyl)bis(4,1-phenyleneoxy)]bis(2-methylbutanoic acid)

2,2'-[Cyclohexylidenebis(4,1-phenyleneoxy)]bis(2-methylbutyric acid)

2,2'-(cyclohexyliden...

2,2,-((cyclohexane-1,1-diylbis(4,1-phenylene))bis(oxy))bis(2-methylbutanoic acid)

2,2'-((Cyclohexane-1,1-diylbis(4,1-phenylene)

bis(2-methylbutanoic acid)

bis(oxy)

2,2’-(4,4’-cyclohexylidenediphenoxy)-2,2’-dimethyldibutyricacid

2,2’-cyclohexane-1,1-diylbis(p-phenyleneoxy)bis-(2-methyl-butyricaci

Clinofibrate &gt

2,2'-(4,4'-Cyclohexylidenediphenoxy)-2,2'-dimethyldibutanoic Acid

Clinofibrate USP/EP/BP

Clinofibrate (10mM in DMSO)

2,2’-[[Cyclohexane-1,1-diylbis(4,1-phenylene)]bis(oxy)]bis(2-methylbutanoic Acid)

30299-08-2

30298-08-2

C28H36O6

API

Inhibitors

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals