HO-PEG5-CH2COOtBu

Product Name: HO-PEG5-CH2COOtBu
CAS No.: 52026-48-9
Chemical Name: HO-PEG5-CH2COOtBu
Synonyms: HO-PEG5-CH2COOH;HO-PEG5-CH2COOtBu;Hydroxy-PEG5-CH2COOH;Hydroxy-PEG5-acetic acid;17-hydroxy-3,6,9,12,15-pentaoxaheptadecanoic acid;Acetic acid, 2-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-;HO-PEG5-CH2COOH/Acetic acid, 2-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
CBNumber: CB93340562
Molecular Formula: C12H24O8
Formula Weight: 296.31
MOL File: 52026-48-9.mol

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HO-PEG5-CH2COOtBu Property

Boiling point:: 444.5±40.0 °C(Predicted)
Density: 1.182±0.06 g/cm3(Predicted)
storage temp.: Store at 0-8 °C
pka: 3.39±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS104050
Product name: HO-PEG5-CH2COOH
Purity: 95+%
Packaging: 250mg
Price: $350
Updated: 2021/12/16

Activate Scientific

Product number: AS104050
Product name: HO-PEG5-CH2COOH
Purity: 95+%
Packaging: 1g
Price: $673
Updated: 2021/12/16

purepeg

Product number: 433805
Product name: HO-PEG5-CH2COOtBu
Purity: min.97%
Packaging: 1g
Price: $300
Updated: 2021/12/16

Acrotein

Product number: B-0936
Product name: HO-PEG5-CH2COOH
Purity: 95%
Packaging: 0.5g
Price: $366.66
Updated: 2021/12/16

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HO-PEG5-CH2COOtBu Chemical Properties,Usage,Production

Uses

HO-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

HO-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

HO-PEG5-CH2COOtBu Preparation Products And Raw materials

Raw materials

Preparation Products

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HO-PEG5-CH2COOtBu Suppliers

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52026-48-9, HO-PEG5-CH2COOtBuRelated Search:

HS-PEG5-CH2CH2COOH Hydroxy-PEG1-methyl ester Hydroxy-PEG2-CH2CO2H Hydroxy-PEG4-CH2CO2Me HO-PEG6-CH2COOH HS-PEG4-CH2CH2COOH HO-PEG3-CH2COOH COOH-PEG10-COOtBu HOOCCH2CH2-PEG16-CH2CH2COOH Acid-PEG4-t-butyl ester HOOCCH2CH2O-PEG10-CH2CH2COOH Hydroxy-PEG5-acid

HO-PEG5-CH2COOtBu

HO-PEG5-CH2COOH

Hydroxy-PEG5-acetic acid

Hydroxy-PEG5-CH2COOH

17-hydroxy-3,6,9,12,15-pentaoxaheptadecanoic acid

HO-PEG5-CH2COOH/Acetic acid, 2-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-

Acetic acid, 2-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-

52026-48-9