ChemicalBook > CAS DataBase List > HO-PEG5-CH2COOtBu

HO-PEG5-CH2COOtBu

Product Name
HO-PEG5-CH2COOtBu
CAS No.
52026-48-9
Chemical Name
HO-PEG5-CH2COOtBu
Synonyms
HO-PEG5-CH2COOH;HO-PEG5-CH2COOtBu;Hydroxy-PEG5-CH2COOH;Hydroxy-PEG5-acetic acid;17-hydroxy-3,6,9,12,15-pentaoxaheptadecanoic acid;Acetic acid, 2-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-;HO-PEG5-CH2COOH/Acetic acid, 2-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
CBNumber
CB93340562
Molecular Formula
C12H24O8
Formula Weight
296.31
MOL File
52026-48-9.mol
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HO-PEG5-CH2COOtBu Property

Boiling point:
444.5±40.0 °C(Predicted)
Density 
1.182±0.06 g/cm3(Predicted)
pka
3.39±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Activate Scientific
Product number
AS104050
Product name
HO-PEG5-CH2COOH
Purity
95+%
Packaging
250mg
Price
$350
Updated
2021/12/16
Activate Scientific
Product number
AS104050
Product name
HO-PEG5-CH2COOH
Purity
95+%
Packaging
1g
Price
$673
Updated
2021/12/16
purepeg
Product number
433805
Product name
HO-PEG5-CH2COOtBu
Purity
min.97%
Packaging
1g
Price
$300
Updated
2021/12/16
Acrotein
Product number
B-0936
Product name
HO-PEG5-CH2COOH
Purity
95%
Packaging
0.5g
Price
$366.66
Updated
2021/12/16
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HO-PEG5-CH2COOtBu Chemical Properties,Usage,Production

Biological Activity

HO-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

HO-PEG5-CH2COOtBu Preparation Products And Raw materials

Raw materials

Preparation Products

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52026-48-9, HO-PEG5-CH2COOtBuRelated Search:


  • HO-PEG5-CH2COOtBu
  • HO-PEG5-CH2COOH
  • Hydroxy-PEG5-acetic acid
  • Hydroxy-PEG5-CH2COOH
  • 17-hydroxy-3,6,9,12,15-pentaoxaheptadecanoic acid
  • HO-PEG5-CH2COOH/Acetic acid, 2-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
  • Acetic acid, 2-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
  • 52026-48-9