ChemicalBook > CAS DataBase List > HO-PEG5-CH2COOtBu
HO-PEG5-CH2COOtBu
- Product Name
- HO-PEG5-CH2COOtBu
- CAS No.
- 52026-48-9
- Chemical Name
- HO-PEG5-CH2COOtBu
- Synonyms
- HO-PEG5-CH2COOH;HO-PEG5-CH2COOtBu;Hydroxy-PEG5-CH2COOH;Hydroxy-PEG5-acetic acid;17-hydroxy-3,6,9,12,15-pentaoxaheptadecanoic acid;Acetic acid, 2-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-;HO-PEG5-CH2COOH/Acetic acid, 2-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
- CBNumber
- CB93340562
- Molecular Formula
- C12H24O8
- Formula Weight
- 296.31
- MOL File
- 52026-48-9.mol
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HO-PEG5-CH2COOtBu Property
- Boiling point:
- 444.5±40.0 °C(Predicted)
- Density
- 1.182±0.06 g/cm3(Predicted)
- pka
- 3.39±0.10(Predicted)
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N-Bromosuccinimide Price
Activate Scientific
- Product number
- AS104050
- Product name
- HO-PEG5-CH2COOH
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $350
- Updated
- 2021/12/16
Activate Scientific
- Product number
- AS104050
- Product name
- HO-PEG5-CH2COOH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $673
- Updated
- 2021/12/16
purepeg
- Product number
- 433805
- Product name
- HO-PEG5-CH2COOtBu
- Purity
- min.97%
- Packaging
- 1g
- Price
- $300
- Updated
- 2021/12/16
Acrotein
- Product number
- B-0936
- Product name
- HO-PEG5-CH2COOH
- Purity
- 95%
- Packaging
- 0.5g
- Price
- $366.66
- Updated
- 2021/12/16
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HO-PEG5-CH2COOtBu Chemical Properties,Usage,Production
Biological Activity
HO-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
HO-PEG5-CH2COOtBu Preparation Products And Raw materials
Raw materials
Preparation Products
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