ChemicalBook > CAS DataBase List > Niazinin
Niazinin
- Product Name
- Niazinin
- CAS No.
- 147821-57-6
- Chemical Name
- Niazinin
- Synonyms
- Niazinin;Carbamothioic acid, N-[[4-[(6-deoxy-α-L-mannopyranosyl)oxy]phenyl]methyl]-, O-methyl ester
- CBNumber
- CB93372666
- Molecular Formula
- C15H21NO6S
- Formula Weight
- 343.39
- MOL File
- 147821-57-6.mol
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Niazinin Property
- Boiling point:
- 527.4±60.0 °C(Predicted)
- Density
- 1.387±0.06 g/cm3(Predicted)
- pka
- 12.93±0.70(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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Niazinin Chemical Properties,Usage,Production
Uses
Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC50 value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity[1][2].
IC 50
Leishmania
References
[1] Amandeep Kaur, et al. Antileishmanial compounds from Moringa oleifera Lam. Z Naturforsch C J Biosci. Mar-Apr 2014;69(3-4):110-6. DOI:10.5560/znc.2013-0159
[2] Shiv Rakesh Naik, et al. Structure-based virtual screening, molecular dynamics and binding affinity calculations of some potential phytocompounds against SARS-CoV-2. J Biomol Struct Dyn. 2021 Mar 8;1-18. DOI:10.1080/07391102.2021.1891969
Niazinin Preparation Products And Raw materials
Raw materials
Preparation Products
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