ChemicalBook > CAS DataBase List > BAY 299

BAY 299

Product Name
BAY 299
CAS No.
2080306-23-4
Chemical Name
BAY 299
Synonyms
CPD1617;BAY 299;BAY-299; BAY 299; BAY299;6-(3-hydroxypropyl)-2-(1,3,6-trimethyl-2-oxobenzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione;6-(3-Hydroxy-propyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-benzo[de]isoquinoline-1,3-dione;6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione;1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-;6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione;8-(3-hydroxypropyl)-3-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-3-azatricyclo[7.3.1.0?,13]trideca-1(13),5,7,9,11-pentaene-2,4-dione
CBNumber
CB93381026
Molecular Formula
C25H23N3O4
Formula Weight
429.47
MOL File
2080306-23-4.mol
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BAY 299 Property

Boiling point:
688.7±55.0 °C(Predicted)
Density 
1.377±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:30.0(Max Conc. mg/mL);69.85(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);69.85(Max Conc. mM)
form 
A crystalline solid
pka
14.98±0.10(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

Cayman Chemical
Product number
19777
Product name
BAY-299
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
19777
Product name
BAY-299
Purity
≥98%
Packaging
5mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
19777
Product name
BAY-299
Purity
≥98%
Packaging
10mg
Price
$169
Updated
2024/03/01
Cayman Chemical
Product number
19777
Product name
BAY-299
Purity
≥98%
Packaging
25mg
Price
$381
Updated
2024/03/01
Tocris
Product number
5970
Product name
BAY299
Purity
≥98%(HPLC)
Packaging
25
Price
$318
Updated
2021/12/16
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BAY 299 Chemical Properties,Usage,Production

Description

BAY-299 is a potent and selective inhibitor of the bromodomain and PHD finger-containing (BRPF) family protein BRD1 (IC50 = 6 nM), also known as BRPF2, and the second bromodomain of transcription initiation factor TFIID subunits 1 (TAF1; IC50 = 13 nM). BAY-299 is >30-fold selective over BRPF1, BRPF3, BRD9, and ATAD2 and is >300-fold selective over BRD4. See the Structural Genomics Consortium (SGC) website for more information.

Uses

BAY 299, is a potent and selective inhibitor of the bromodomain and PHD finger-containing (BRPF) family protein BRD1, also known as BRPF2, and a strong inhibitor of TAF1/TAF1L BD2. These proteins play important roles in transcription regulation.

storage

Store at -20°C

BAY 299 Preparation Products And Raw materials

Raw materials

Preparation Products

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BAY 299 Suppliers

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ShangHai Caerulum Pharma Discovery Co., Ltd.
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2080306-23-4, BAY 299Related Search:

T-26c AZD-7594 4-[4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]-benzonitrile ABBV-744 Zofluza intermediate RGX-104 HCl Adavivint

  • BAY-299; BAY 299; BAY299
  • 6-(3-hydroxypropyl)-2-(1,3,6-trimethyl-2-oxobenzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione
  • BAY 299
  • CPD1617
  • 6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
  • 1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-
  • 6-(3-Hydroxy-propyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-benzo[de]isoquinoline-1,3-dione
  • 6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
  • 8-(3-hydroxypropyl)-3-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-3-azatricyclo[7.3.1.0?,13]trideca-1(13),5,7,9,11-pentaene-2,4-dione
  • 2080306-23-4