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Zofluza intermediate

Product Name
Zofluza intermediate
CAS No.
1985607-83-7
Chemical Name
Zofluza intermediate
Synonyms
7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-ol;BM-B60;CPD1605;Zofluza intermediate;Baloxavir Impurity 8;Zofluza intermediate-M6;Baloxavixate Impurity 3;Baloxavir Intermediate 1;Baloxavirmarboxilsidechain;Baloxavir Marboxil Impurity 7
CBNumber
CB33380991
Molecular Formula
C14H10F2OS
Formula Weight
264.29
MOL File
1985607-83-7.mol
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Zofluza intermediate Property

Boiling point:
379.5±42.0 °C(Predicted)
Density 
1.400±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, sealed storage, away from moisture and light
pka
12.57±0.20(Predicted)
Appearance
Off-white to light yellow Solid
optical activity
16.5364°(C=1.0046g/100ml CHCL3)
InChI
InChI=1S/C14H10F2OS/c15-11-6-5-8-10(13(11)16)7-18-12-4-2-1-3-9(12)14(8)17/h1-6,14,17H,7H2
InChIKey
OBEXFUFBCNVOKB-UHFFFAOYSA-N
SMILES
S1CC2=C(F)C(F)=CC=C2C(O)C2=CC=CC=C12
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Chemenu
Product number
CM327353
Product name
7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-ol
Purity
95%+
Packaging
1000g
Price
$4160
Updated
2021/12/16
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Zofluza intermediate Chemical Properties,Usage,Production

Uses

7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-ol is an impurity of Baloxavir Marboxil (B116325) which is an inhibitor of the cap-dependent endonuclease of influenza A and B viruses.

Zofluza intermediate Preparation Products And Raw materials

Raw materials

Preparation Products

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Zofluza intermediate Suppliers

Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd
Tel
13801208576
Fax
010-64215766
Email
maggie@chinazhongshuo.com
Country
China
ProdList
77
Advantage
65
Chengdu anman biomedical technology co., LTD
Tel
028-86617873 18113025300
Email
yukijiangli@amanbio.com
Country
China
ProdList
117
Advantage
58
Jiangsu Vcare PharmaTech Co., Ltd.
Tel
025-58741518 13327700685
Fax
+86-25-58744115
Email
sales@vcarepharmatech.com
Country
China
ProdList
308
Advantage
61
Heading (Nanjing)Pharmtechnologies Co., Ltd.
Tel
025-58467899-832 13382406280
Fax
025-58467899
Email
liucheng@headingpharm.com
Country
China
ProdList
45
Advantage
58
Shandong Shining Pharm Co.,Ltd
Tel
18866891188
Email
zhaojiangxia@shiningpharm.com
Country
China
ProdList
172
Advantage
58
Jinan Chenghui Shuangda biological Co., LTD
Tel
0531-0531-58897003 15550412551
Fax
0531-58897003
Email
market@jnchsd.com
Country
China
ProdList
229
Advantage
62
Beijing Huikang Boyuan Chemical Tech Co., Ltd
Tel
010-68862197 13810598707
Fax
010-68882204
Email
sales@huikangchem.com
Country
China
ProdList
109
Advantage
61
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7471
Advantage
65
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View Lastest Price from Zofluza intermediate manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD
Product
7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-ol 1985607-83-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2025-09-19
Jinan Ruitong Biotech Co., Ltd.
Product
7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-ol 1985607-83-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2025-08-25
Henan Aochuang Chemical Co.,Ltd.
Product
Zofluza intermediate 1985607-83-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-27

1985607-83-7, Zofluza intermediateRelated Search:


  • Zofluza intermediate
  • CPD1605
  • 7,8-difluoro-6,11-dihydro-Dibenzo[b,e]thiepin-11-ol
  • Baloxavir Impurity 8
  • tert-butyl (3-(benzyloxy)-4-oxo-2-((2-(2-oxoethoxy)ethyl)carbamoyl)pyridin-1(4H)-yl)carbamate
  • BM-B60
  • 7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-ol
  • Dibenzo[b,e]thiepin-11-ol, 7,8-difluoro-6,11-dihydro-
  • 7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-ol / Baloxavir Marboxil intermediate
  • Baloxavir Marboxil Impurity 7
  • 7,8-Difluoro-11-hydroxy-6,11-dihydrodibenzo[b,e]thiepine
  • Zofluza intermediate-M6
  • 7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin-
  • Baloxavir Intermediate 1
  • 7,8-difluoro-6,11-dihydrodibenzo [b, e] thiophene-11-ol
  • 7,8-difluoro-6,11-dihydrodibenzo [b, e] thiophen-11-ol
  • Baloxavixate Impurity 3
  • Baloxavirmarboxilsidechain
  • 1985607-83-7
  • 1985607-83-7