ChemicalBook > CAS DataBase List > (R)-2-Methyl-pyrrolidine

(R)-2-Methyl-pyrrolidine

Product Name
(R)-2-Methyl-pyrrolidine
CAS No.
41720-98-3
Chemical Name
(R)-2-Methyl-pyrrolidine
Synonyms
(2R)-2-Methylpyrrolidine;C-3166R;D-2-METHYLPYRROLIDINE;Methylpyrrolidine hcl;2-(R)-Methylpyrrolidine;METHYLPYRROLIDINE(S-2-);(R)-2-METHYL-PYRROLIDINE;(2R)-2-Methylpyrrolidine hcl;Pyrrolidine, 2-methyl-, (2R)-;(2R)-2-Methylpyrrolidinehydrochloride
CBNumber
CB9343250
Molecular Formula
C5H11N
Formula Weight
85.15
MOL File
41720-98-3.mol
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(R)-2-Methyl-pyrrolidine Property

Boiling point:
94 °C(Press: 728 Torr)
Density 
0.842
refractive index 
1.4353
Flash point:
45 ºF
storage temp. 
2-8°C
pka
10.93±0.10(Predicted)
form 
oil
color 
Colourless to pale yellow
Water Solubility 
Insoluble in water.
CAS DataBase Reference
41720-98-3(CAS DataBase Reference)
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Safety

Hazard Codes 
C,F
Risk Statements 
11-22-34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2924
WGK Germany 
3
Hazard Note 
Corrosive/Highly Flammable
HazardClass 
3
PackingGroup 
Ⅱ
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
679097
Product name
(R)-(?)-2-Methylpyrrolidine
Packaging
1g
Price
$186
Updated
2024/03/01
Alfa Aesar
Product number
H57885
Product name
(R)-(-)-2-Methylpyrrolidine, 95%
Packaging
250mg
Price
$38.65
Updated
2024/03/01
Alfa Aesar
Product number
H57885
Product name
(R)-(-)-2-Methylpyrrolidine, 95%
Packaging
1g
Price
$114.65
Updated
2024/03/01
Activate Scientific
Product number
AS44074-A
Product name
(R)-2-Methylpyrrolidine
Purity
95% ee
Packaging
1g
Price
$147
Updated
2021/12/16
Chem-Impex
Product number
41536
Product name
(R)-(-)-2-Methylpyrrolidine,≥95%(GC)Hazmat
Purity
≥95%(GC)
Packaging
1G
Price
$156.08
Updated
2021/12/16
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(R)-2-Methyl-pyrrolidine Chemical Properties,Usage,Production

Uses

It is used as a building block used in a multikilogram synthesis of a chiral naphthalenoid histamine receptor antagonist.

Definition

ChEBI: (R)-2-methylpyrrolidine is a 2-methylpyrrolidine that has (R)-configuration. It is a conjugate base of a (R)-2-methylpyrrolidinium.

Application

(R)-2-Methyl-pyrrolidine, an optically active amine that can be used as a key building block to synthesize:
4,5-fused pyridazinone derivatives are applicable as potent histamine H3 receptor antagonists.
Naphthalenoid histamine H3 receptor antagonist.
Pyrrolo[2,3-d]pyrimidine derivatives as potent inhibitors of leucine-rich repeat kinase 2.

References

Synthesis and structure-activity relationships of 4,5-fused pyridazinones as histamine H3 receptor antagonists. DOI:10.1016/j.bmcl.2011.08.045
Efficient and Practical Synthesis of (R)-2-Methylpyrrolidine DOI:10.1021/jo060319n

(R)-2-Methyl-pyrrolidine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (R)-2-Methyl-pyrrolidine manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
(R)-2-Methyl-pyrrolidine 41720-98-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-17
Zhuozhou Wenxi import and Export Co., Ltd
Product
(R)-2-Methylpyrrolidine 41720-98-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
(R)-2-Methylpyrrolidine 41720-98-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

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  • METHYLPYRROLIDINE(S-2-)
  • D-2-METHYLPYRROLIDINE
  • (R)-2-METHYL-PYRROLIDINE
  • (2R)-2-Methylpyrrolidine
  • (2R)-2-Methylpyrrolidinehydrochloride
  • (2R)-2-Methylpyrrolidine hcl
  • C-3166R
  • 2-(R)-Methylpyrrolidine
  • Methylpyrrolidine hcl
  • Pyrrolidine, 2-methyl-, (2R)-
  • (R)-2-Methyl-pyrrolidine ISO 9001：2015 REACH
  • 41720-98-3
  • Pyrrolidines
  • Heterocyclic Building Blocks
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Heterocyclic Building Blocks
  • Pyrrolidines
  • Chiral Compound
  • Chiral Building Blocks
  • Benzenes
  • Heterocyclic Series