Adenosine 5'-monophosphate monohydrate

ChemicalBook > CAS DataBase List > Adenosine 5'-monophosphate monohydrate

Adenosine 5'-monophosphate monohydrate

Pharmacodynamics

Product Name: Adenosine 5'-monophosphate monohydrate
CAS No.: 18422-05-4
Chemical Name: Adenosine 5'-monophosphate monohydrate
Synonyms: A-5'-P;5'-AMP;AMP.H2O;5'-AMPH2;5'-AMP H2O;AMP monohydrate;5'-AMP MONOHYDRATE;5'-AMP=Adenylicacid;Adenosine-5’-phospho;Bucladesine Impurity 4
CBNumber: CB9343816
Molecular Formula: C10H16N5O8P
Formula Weight: 365.24
MOL File: 18422-05-4.mol

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Adenosine 5'-monophosphate monohydrate Property

Melting point:: 183-188 °C (dec.)(lit.)
alpha: -48 º (c=2% in 2% NaOH)
FEMA: 4224 | ADENOSINE MONOPHOSPHATE; MONOSODIUM, OR DISODIUM ADENYLATE
storage temp.: -20°C
solubility: H₂O: with addition of mild alkalisoluble
form: Solid
color: White to Off-White
Merck: 14,158
BRN: 5205540
CAS DataBase Reference: 18422-05-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: AU7480500
F: 8-10-21
TSCA: Yes
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A2252
Product name: Adenosine 5′-monophosphate monohydrate
Purity: from yeast, ≥97%
Packaging: 5g
Price: $62.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: A2252
Product name: Adenosine 5′-monophosphate monohydrate
Purity: from yeast, ≥97%
Packaging: 25g
Price: $228
Updated: 2024/03/01

Sigma-Aldrich

Product number: A2252
Product name: Adenosine 5′-monophosphate monohydrate
Purity: from yeast, ≥97%
Packaging: 100g
Price: $637
Updated: 2024/03/01

TRC

Product number: A281830
Product name: Adenosine 5′-monophosphate monohydrate
Packaging: 50mg
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-8159
Product name: Adenosine 5′-monophosphate monohydrate
Purity: 99.07%
Packaging: 500mg
Price: $50
Updated: 2021/12/16

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Adenosine 5'-monophosphate monohydrate Chemical Properties,Usage,Production

Pharmacodynamics

Adenosine monophosphate, also known as 5'-adenylic acid and abbreviated AMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside adenosine. AMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase adenine. AMP is used as a dietary supplement to boost immune activity, and is also used as a substitute sweetener to aid in the maintenance of a low-calorie diet.

Chemical Properties

White crystalline powder

Uses

Nutrient;Ca++ channel block

Uses

Adenosine 5′-monophosphate (5′AMP) is suitable for use as

a reagent in the synthesis of adenosine-5′-phosphoimidazolide
an activator of phosphorylase b in the polymerization reaction for the synthesis of branched polysaccharides
an inhibitor of endogenous NMN adenylyltransferase (NMNAT) activity that converts NMN to NAD⁺

Definition

ChEBI: Adenosine 5'-monophosphate monohydrate is a purine ribonucleoside monophosphate.

Biochem/physiol Actions

Adenosine 5′-monophosphate (5′-AMP) has many uses in nature. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). AMP inhibits dephosphorylation of AMPK and promotes phosphorylation of AMPK by upstream kinases.

Purification Methods

The acid has been recrystallised from H2O (fine needles) and is freely soluble in boiling H2O. It crystallises also from H2O on addition of acetone. Alternatively purify it by chromatography on Dowex 1 (in formate form), eluting with 0.25M formic acid. It is then adsorbed onto charcoal (which had been boiled for 15minutes with M HCl, washed free of chloride and dried at 100o) and recovered by stirring three times with isoamyl alcohol/H2O (1:9 v/v). The aqueous layer from the combined extracts is evaporated to dryness under reduced pressure, and the product is crystallised twice from hot H2O. [Morrison & Doherty Biochem J 79 433 1961]. It has max 259nm ( 15,400) in H2O at pH 7.0. [Alberty et al. J Biol Chem 193 425 1951, Martell & Schwarzenbach Helv Chim Acta 39 653 1956]. The acridinium salt has m 208o [Baddiley & Todd J Chem Soc 648 1947, Pettit Synthetic Nucleotides, van Nostrand-Reinhold, NY, Vol 1 252 1972, NMR: Sarma et al. J Am Chem Soc 96 7337 1974, Norton et al. J Am Chem Soc 98 1007 1976, IR of diNa salt: Miles Biochem Biophys Acta 27 324 1958]. [Beilstein 26 III/IV 3615.]

Adenosine 5'-monophosphate monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Adenosine 5'-monophosphate monohydrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Adenosine 5'-monophosphate monohydrate 18422-05-4
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 500kgs
Release date: 2021-09-08

Henan Aochuang Chemical Co.,Ltd.

Product: Adenosine 5'-monophosphate monohydrate 18422-05-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-29

Career Henan Chemical Co

Product: Adenosine 5'-monophosphate monohydrate 18422-05-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%-99.99%
Supply Ability: 1kg-10MT
Release date: 2019-05-24

18422-05-4, Adenosine 5'-monophosphate monohydrateRelated Search:

MELIBIOSE 2-Amino-2-methyl-1-propanol Cyclic AMP Adenosine Adenosine 5'-monophosphate ADP Adenosine5'-(tetrahydrogen triphosphate), disodiuM salt, trihydrate (9CI) ADENOSINE 5'-TRIPHOSPHATASE Vidarabine monophosphate ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT ATP disodium salt ADENOSINE 5'-DIPHOSPHATE SODIUM SALT ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL& Adenosine 3',5'-cyclic monophosphate sodium salt NADP sodium salt Nadph tetrasodium salt FLAVIN ADENINE DINUCLEOTIDE NAD+

ADENOSINE 5'-MONOPHOSPHATE FREE ACID97+% FROM YEAS

5'-AMP=Adenylicacid

ADENOSINE-5'-MONOPHOSPHATE 1-HYDRATE

5'-AMP H2O

5'-AMP MONOHYDRATE

ADENOSINE 5'-MONOPHOSPHATE MONOHYDRATE

ADENOSINE 5'-MONOPHOSPHORIC ACID MONOHYDRATE

ADENYLIC ACID MONOHYDRATE

A-5'-P

Adenosine-5'-monophosphoric acid monohydrate >96%

AMP monohydrate

5-Adenylic acid, monohydrate

Adenosine-5''-monophosphoric acid (and/or unspecified salts)

5'-AMP

[(2R,3R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-2-oxolanyl]methyl dihydrogen phosphate

Adenosine 5'-monophosphate monohydrate, from yeast,≥97%

5'-AMPH2

Adenosine-5'-Monophosphoric acid Monhydrate >96%

5μ-AMP, Adenylic acid from muscle, AMP

5μ-Adenylic acid, 5μ-AMP, A-5μ-P, AMP

Adenosine-5'-monophosphate(AMP),free acid

Adenosine 5′-monophosphate monohydrate,5′-AMP, 5′-Adenylic acid, A-5′-P, AMP

Adenosine-5’-phospho

AMP.H2O

5'-Adenylic acid, hydrate (1:1)

Adenosine-5'-monophosphate monohydrate≥ 95% (HPLC)

Adenosine 5'-Monophosphate, Free Acid, from Yeast(AMP)

Bucladesine Impurity 4

Adenosine- 5-monophosphate monohydrate, free acid

((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate hydrate

Bucladesine Impurity 5

Enzastaurin Impurity 9

Adenosine 5'-monophosphate monohydratefrom yeast

Adenosine 5'-monophosphate monohydrate

18422-05-4

C10H12N5O6PH2O

C10H16N5O8P

BioChemical

Biochemicals and Reagents

Nucleosides, Nucleotides, Oligonucleotides

Nucleotides

nucleoside

Nucleotides and Nucleic Acids