Boc-Lys-OH
- Product Name
- Boc-Lys-OH
- CAS No.
- 13734-28-6
- Chemical Name
- Boc-Lys-OH
- Synonyms
- BOC-LYS;BOC-LYS-OH;BOC-L-LYSINE;BOC-LYSINE;N-ALPHA-T-BOC-L-LYSINE;NSC 343721;BOC-L-LYS-OH;Boc-Lys-OH 99%;Boc-Lys-OH,97%;N2-Boc-L-lysine
- CBNumber
- CB9345067
- Molecular Formula
- C11H22N2O4
- Formula Weight
- 246.3
- MOL File
- 13734-28-6.mol
Boc-Lys-OH Property
- Melting point:
- ~205 °C (dec.)(lit.)
- alpha
- 22 º (c=2, CH3OH)
- Boiling point:
- 389.3°C (rough estimate)
- Density
- 1.1313 (rough estimate)
- refractive index
- 21.5 ° (C=2, MeOH)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Acetic Acid (Slightly), Methanol (Slightly, Sonicated), Water (Slightly, Heated,
- form
- Powder
- pka
- 3.92±0.21(Predicted)
- color
- White
- optical activity
- [α]20/D +4.6±0.5°, c = 2% in H2O
- Water Solubility
- Soluble in water. Slightly soluble in methanol.
- BRN
- 4252546
- Sequence
- {Boc-Lys}
- InChI
- InChI=1S/C11H22N2O4/c1-11(2,3)17-10(16)13-8(9(14)15)6-4-5-7-12/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m0/s1
- InChIKey
- DQUHYEDEGRNAFO-QMMMGPOBSA-N
- SMILES
- C(O)(=O)[C@H](CCCCN)NC(OC(C)(C)C)=O
- CAS DataBase Reference
- 13734-28-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 3
- HS Code
- 2924 19 00
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 8.53017
- Product name
- Boc-Lys-OH
- Purity
- Novabiochem?
- Packaging
- 25g
- Price
- $473
- Updated
- 2025/07/31
- Product number
- 15456
- Product name
- Boc-Lys-OH
- Purity
- ≥99.0% (NT)
- Packaging
- 5g
- Price
- $231
- Updated
- 2025/07/31
- Product number
- 15456
- Product name
- Boc-Lys-OH
- Purity
- ≥99.0% (NT)
- Packaging
- 25g
- Price
- $1040
- Updated
- 2025/07/31
- Product number
- B1669
- Product name
- Nalpha-(tert-Butoxycarbonyl)-L-lysine
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $72
- Updated
- 2025/07/31
- Product number
- 359688
- Product name
- Boc-Lys-OH
- Purity
- 99%
- Packaging
- 1g
- Price
- $96.8
- Updated
- 2025/07/31
Boc-Lys-OH Chemical Properties,Usage,Production
Chemical Properties
white to off-white powder
Uses
N-Boc-L-lysine is a protected analogue of a major amino acid participating in the binding of AcH to proteins. N-Boc-L-lysine as well as other t-butoxycarbonyl (Boc) amino acids can be converted to their respective amino acids via cleavage of the urethane bond.
Uses
Boc-Lys-OH (Nα-Boc-L-lysine) can be used as a building block to synthesize:
A heterotrifunctional peptide-based linker molecule applicable as a bio-labeling reagent.
Lysine derivatives of azamacrocycle and anthraquinone.
Boc-Lys(Bn4-DTPA)-OH, a precursor to synthesize diethylene triamine pentaacetic acid (DTPA) containing peptides.
A ferrocene-amino acid conjugate which is used in developing chemical warfare agent (CWA) sensor.
Production Methods
L-lysine was added to acetone and Et3N under stirring at 25 °C. After that, di-tert-butyl dicarbonate was added. After 4.5 h, decompression evaporates acetone, and the water layer is extracted with ethyl ether 3 times. The dilute HC1 was added to the aqueous layer to adjust pH 2-3. The crude product was purified to obtain Boc-Lys-OH.
reaction suitability
Boc solid-phase peptide synthesis
References
[1] Patent: CN102993200, 2016, B. Location in patent: Paragraph 0050; 0051; 0052
[2] Journal of Materials Chemistry B, 2014, vol. 2, # 42, p. 7351 - 7359
[3] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995, vol. 34, # 1, p. 45 - 47
[4] Chinese Chemical Letters, 2012, vol. 23, # 3, p. 297 - 300
[5] Patent: CN103833623, 2016, B. Location in patent: Paragraph 0058; 0059; 0062
Boc-Lys-OH Preparation Products And Raw materials
Raw materials
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View Lastest Price from Boc-Lys-OH manufacturers
- Product
- Boc-Lys-OH 13734-28-6
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1000kgs
- Release date
- 2021-09-23
- Product
- N-alpha-(tert-Butoxycarbonyl)-L-lysine 13734-28-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2024-12-03
- Product
- Boc-L-Lys-OH 13734-28-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2023-09-27