Geniposide

Pharmacological effects

Product Name: Geniposide
CAS No.: 24512-63-8
Chemical Name: Geniposide
Synonyms: Geniposidic;Genipin 1-glucoside;GENIPOSIDE;Geniposide>Geniposide(P);Geniposide-RM;Olea europaea L;Geniposide ,98%;Geniposide (8CI);TIANFU-CHEM Geniposide
CBNumber: CB9347733
Molecular Formula: C17H24O10
Formula Weight: 388.37
MOL File: 24512-63-8.mol

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Geniposide Property

Melting point:: 160.0 to 164.0 °C
Boiling point:: 641.4±55.0 °C(Predicted)
Density: 1.54±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: H2O: ≥5mg/mL
form: powder
pka: 12.80±0.70(Predicted)
color: white to beige
Stability:: Hygroscopic
InChIKey: IBFYXTRXDNAPMM-BWBTYKGONA-N
SMILES: C12C(CO)=CCC1C(C(=O)OC)=CO[C@H]2O[C@H]1[C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O |&1:14,16,17,19,20,22,r|
LogP: -1.920 (est)
CAS DataBase Reference: 24512-63-8(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0153
Product name: Geniposide
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $228
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0153
Product name: Geniposide
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $885
Updated: 2024/03/01

TCI Chemical

Product number: G0385
Product name: Geniposide
Purity: >95.0%(HPLC)
Packaging: 100mg
Price: $89
Updated: 2024/03/01

TCI Chemical

Product number: G0385
Product name: Geniposide
Purity: >95.0%(HPLC)
Packaging: 1g
Price: $370
Updated: 2024/03/01

Cayman Chemical

Product number: 28281
Product name: Geniposide
Packaging: 100mg
Price: $61
Updated: 2024/03/01

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Geniposide Chemical Properties,Usage,Production

Pharmacological effects

Geniposide, also known as Gardenia glycosides, geniposide. It is a brown to white crystalline powder, with little flavor and no bitter taste, a cycloolefin ether glycoside compound extracted from the dry and ripe fruit of Rubiaceae Gardenia. Geniposide has a significant role in promoting bile secretion, and can reduce blood bilirubin, as well as promote rapid excretion of bilirubin in the blood. It has an inhibitory effect on Streptococcus hemolyticus and skin fungi. It also has antipyretic, analgesic, sedative, antihypertensive and hemostatic effects. Geniposide has the function of purging pathogenic fire and eliminating restlessness, clearing heat and eliminating damp, decreasing swellinging to relieving pain. The Indications of Geniposide are heat disease, dysphoria, coma delirium, jaundice, heat stranguria, heat in blood, swelling and pain of eye, pathopyretic ulcer, and sprain.

Chemical Properties

White powder

Uses

Geniposide is an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis. Geniposide is one of the biologically active ingredients of gardenia fruit. Geniposide is widely used in multi-component injection in the treatment of cerebrovascula

Definition

ChEBI: Geniposide is a terpene glycoside.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation and upregulate downstream antioxidant protein HO-1 expression through the PI3K/Akt signaling pathway, which may account for its neuroprotective and antioxidative activity. Glucagon-like peptide 1 (GLP-1) receptor may also play a critical role in geniposide induced HO-1 expression.

Geniposide Preparation Products And Raw materials

Raw materials

Preparation Products

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Geniposide Suppliers

Americas 1 China 336 Czech Republic 1 Europe 1 Germany 2 India 3 Japan 4 Switzerland 1 United Kingdom 10 United States 36 Global 395

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View Lastest Price from Geniposide manufacturers

Hovane Phytochemicals Co., Ltd

Product: Geniposide 24512-63-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%HPLC
Supply Ability: 1 ton
Release date: 2024-11-07

BINBO BIOLOGICAL CO.,LTD

Product: Geniposide 24512-63-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000 kg
Release date: 2024-04-26

Hebei Weibang Biotechnology Co., Ltd

Product: Geniposide 24512-63-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-31

24512-63-8, GeniposideRelated Search:

Methyl acrylate Crocin Methylparaben Methyl acetate Genipin Thiophanate-methyl Kresoxim-methyl Bensulfuron methyl GARDENOSIDE 14,15β-Epoxy-3β-hydroxy-19-oxo-5β,14β-bufa-20,22-dienolide Methyl Timosaponin A-III Timosaponin BII Sarsasapogenin Sesamol Anemarsaponin E SESAMOLIN Sesamin

GENIPOSIDE

Methyl (1R,2S,6S)-9-(hydroxymethyl)-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-oxabicyclo[4.3.0]nona-4,8-diene-5-carboxylate

glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)-,methyl ester, (1S,4aS,7aS)-

(1S)-1α-(β-D-Glucopyranosyloxy)-1,4aα,5,7aα-tetrahydro-7-hydroxymethylcyclopenta[c]pyran-4-carboxylic acid methyl ester

1α-(β-D-Glucopyranosyloxy)-1,4aα,5,7aα-tetrahydro-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid methyl ester

Geniposide ,98%

Olea europaea L

Geniposidic

Methyl (1S)-1alpha-(beta-D-Glucopyranosyloxy)-7-(hydroxymethyl)-1,4aalpha,5,7aalpha-tetrahydrocyclopenta[c]pyran-4-carboxylate (1S)-1alpha-(beta-D-Glucopyranosyloxy)-7-(hydroxymethyl)-1,4aalpha,5,7aalpha-tetrahydrocyclopenta[c]pyran-4-carboxylic Acid Meth

Genipin 1-glucoside

Geniposide, 98%, from Gardenia jasminoides Ellis

7-(hydroxymethyl)-1-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid methyl ester

Geniposide Jasminoidin 24512-63-8

Geniposide, froM Gardenia jasMinoides Ellis

Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxyMethyl)-, Methyl ester, (1S,4aS,7aS)-

(1S,4aS,7aS)-methyl 7-(hydroxymethyl)-1-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate

(1S,4αS,7αS)- 1-(β-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)- cyclopenta[c]pyran-4-carboxylic acid methyl ester

Geniposide, 98%, from Gardenia jasminoides J. Ellis

Ethyl (1S,4aS,7aS)-1-(β-D-glucopyranoside)-7-hydroxymethyl-1,4a,5,7a-tetrahydrocydopenta[c]pyran-4-carboxylate

Geniposide&gt

Gardenia extract Gardenoside

(1S)-1alpha-(beta-D-Glucopyranosyloxy)-7-(hydroxymethyl)-1,4a alpha,5,7a alpha-tetrahydrocyclopenta[c]pyran-4-carboxylic Acid Me

Methyl (1S)-1alpha-(beta-D-Glucopyranosyloxy)-7-(hydroxymethyl)-1,4aalpha,5,7aalpha-tetrahydrocyclopenta[c]pyran-4-carboxylate

TIANFU-CHEM Geniposide

Geniposide (8CI)

Geniposide (gardenia extract) 70%

Geniposide(P)

Geniposide-RM

24512-63-8

24152-63-8

24512-61-8

C17H24O10

Inhibitors

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Glucagon receptor and related

Natural Plant Extract

Standard extract

Iridoids