5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE
- Product Name
- 5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE
- CAS No.
- 146709-78-6
- Chemical Name
- 5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE
- Synonyms
- ZD7155HCl;ZD 7155 HYDROCHLORIDE;ZD7155 hydrochloride >=97% (HPLC);5,7-Diethyl-3,4-dihydro-1-[[2(1H-tetrazol-5-yl)[1,1biphenyl]-4-yl]methyl]-1,6-naphthyridin-2(1H)-onehydrochloride;5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE;1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-5,7-diethyl-3,4-dihydro-1,6-naphthyridin-2(1H)-one hydrochloride;1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-5,7-diethyl-3,4-dihydro-1,6-naphthyridin-2(1H)-one hydrochloride
- CBNumber
- CB9360710
- Molecular Formula
- C26H27ClN6O
- Formula Weight
- 474.99
- MOL File
- 146709-78-6.mol
5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE Property
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMSO: 10 mM
- form
- Powder
- color
- White to yellow
- Water Solubility
- Soluble to 10 mM in water with gentle warming
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 1211
- Product name
- ZD7155hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $187
- Updated
- 2021/12/16
- Product number
- 1211
- Product name
- ZD7155hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $787
- Updated
- 2021/12/16
- Product number
- Z157508
- Product name
- ZD7155Hydrochloride
- Packaging
- 10mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- CS-0024625
- Product name
- ZD7155(hydrochloride)
- Purity
- 98.32%
- Packaging
- 5mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 3387CR
- Product name
- ZD7155hydrochloride
- Packaging
- 10mg
- Price
- $230
- Updated
- 2021/12/16
5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
ZD 7155 Hydrochloride, is a potent and selective competitive antagonist for the angiotensin II type 1 (AT1) receptor. it is shown to be more active than the prototype AT1 antagonist, losartan, and it’s orally active.
Biological Activity
A potent and selective competitive antagonist for the angiotensin II type 1 (AT 1 ) receptor. Displaces [ 125 I]-angiotensin II binding with an IC 50 value of 3.8 nM in guinea pig adrenal gland membranes. Orally active, and is more potent and longer-acting than the prototype AT 1 antagonist, losartan.
storage
Desiccate at +4°C
5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE Suppliers
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