5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE

Product Name: 5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE
CAS No.: 146709-78-6
Chemical Name: 5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE
Synonyms: ZD7155HCl;ZD 7155 HYDROCHLORIDE;ZD7155 hydrochloride >=97% (HPLC);5,7-Diethyl-3,4-dihydro-1-[[2(1H-tetrazol-5-yl)[1,1biphenyl]-4-yl]methyl]-1,6-naphthyridin-2(1H)-onehydrochloride;5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE;1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-5,7-diethyl-3,4-dihydro-1,6-naphthyridin-2(1H)-one hydrochloride;1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-5,7-diethyl-3,4-dihydro-1,6-naphthyridin-2(1H)-one hydrochloride
CBNumber: CB9360710
Molecular Formula: C26H27ClN6O
Formula Weight: 474.99
MOL File: 146709-78-6.mol

More

Less

5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE Property

storage temp.: Inert atmosphere,2-8°C
solubility: DMSO: 10 mM
form: Powder
Water Solubility: Soluble to 10 mM in water with gentle warming

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Tocris

Product number: 1211
Product name: ZD7155hydrochloride
Purity: ≥98%(HPLC)
Packaging: 10
Price: $187
Updated: 2021/12/16

Tocris

Product number: 1211
Product name: ZD7155hydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $787
Updated: 2021/12/16

TRC

Product number: Z157508
Product name: ZD7155Hydrochloride
Packaging: 10mg
Price: $180
Updated: 2021/12/16

ChemScene

Product number: CS-0024625
Product name: ZD7155(hydrochloride)
Purity: 98.32%
Packaging: 5mg
Price: $150
Updated: 2021/12/16

AK Scientific

Product number: 3387CR
Product name: ZD7155hydrochloride
Packaging: 10mg
Price: $230
Updated: 2021/12/16

More

Less

5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

ZD 7155 Hydrochloride, is a potent and selective competitive antagonist for the angiotensin II type 1 (AT1) receptor. it is shown to be more active than the prototype AT1 antagonist, losartan, and it’s orally active.

Biological Activity

A potent and selective competitive antagonist for the angiotensin II type 1 (AT 1 ) receptor. Displaces [ 125 I]-angiotensin II binding with an IC 50 value of 3.8 nM in guinea pig adrenal gland membranes. Orally active, and is more potent and longer-acting than the prototype AT 1 antagonist, losartan.

storage

Desiccate at +4°C

5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE Suppliers

China 18 Germany 1 India 1 United Kingdom 3 United States 7 Global 30

146709-78-6, 5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDERelated Search:

ZD 7155 ICI D7114 1-METHYL-1,2,3,4-TETRAHYDRO-[1,6]NAPHTHYRIDINE 4-PYRIDINAMINE, 5-ETHYL-2-METHYL- 2,6-DIMETHYL-PYRIDIN-4-YLAMINE 3,4-DIHYDRO-1,6-NAPHTHYRIDIN-2(1H)-ONE C-BIPHENYL-4-YL-METHYLAMINE HYDROCHLORIDE 1,2,3,4-TETRAHYDRO-1,6-NAPHTHYRIDINE Acetamide,N-(2-methyl-4-pyridinyl)- 5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE

ZD 7155 HYDROCHLORIDE

5,7-DIETHYL-3,4-DIHYDRO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,6-NAPHTHYRIDIN-2(1H)-ONE HYDROCHLORIDE

5,7-Diethyl-3,4-dihydro-1-[[2(1H-tetrazol-5-yl)[1,1biphenyl]-4-yl]methyl]-1,6-naphthyridin-2(1H)-onehydrochloride

ZD7155HCl

ZD7155 hydrochloride >=97% (HPLC)

1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-5,7-diethyl-3,4-dihydro-1,6-naphthyridin-2(1H)-one hydrochloride

146709-78-6

C26H27ClN6O

C26H26N6OHCl