ChemicalBook > CAS DataBase List > Eprazinone dihydrochloride

Eprazinone dihydrochloride

Product Name
Eprazinone dihydrochloride
CAS No.
10402-53-6
Chemical Name
Eprazinone dihydrochloride
Synonyms
746CE;Mucitux;Eftapan;Resplen;Rozuplen;NSC 317935;Eprazinone 2HCl;Eprazinone diHCl;EPRAZINONE HYDROCHLORIDE;Eprazinone 2hydrochloride
CBNumber
CB9371811
Molecular Formula
C24H33ClN2O2
Formula Weight
416.99
MOL File
10402-53-6.mol
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Eprazinone dihydrochloride Property

Melting point:
201° (Toffel-Nadolny, Gielsdorf); mp 160° (Mauvernay)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
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Safety

Toxicity
LD50 in mice (mg/kg): 729 orally, 38 i.v. (Vacher)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
448353
Product name
Eprazinone Dihydrochloride
Packaging
50mg
Price
$355
Updated
2021/12/16
TRC
Product number
E590020
Product name
EprazinoneDihydrochloride
Packaging
250mg
Price
$215
Updated
2021/12/16
ChemScene
Product number
CS-0019683
Product name
Eprazinonedihydrochloride
Packaging
250mg
Price
$225
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
94335
Product name
Eprazinone Dihydrochloride
Packaging
50mg
Price
$375
Updated
2021/12/16
ChemScene
Product number
CS-0019683
Product name
Eprazinonedihydrochloride
Packaging
500mg
Price
$380
Updated
2021/12/16
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Eprazinone dihydrochloride Chemical Properties,Usage,Production

Originator

Mucitux,Riom,France,1969

Uses

Eprazinone Dihydrochloride is a drug used to improve pulmonary function in patients with chronic bronchitis.

Definition

ChEBI: A hydrochloride obtained by combining eprazinone with two molar equivalents of hydrochloric acid.

Manufacturing Process

61.4 g of 0.2M of 1-(2-phenyl-2-ethoxy)piperazine dihydrochloride, 33.5 g (0.25M) propiophenone, 75 g (0.25M) trioxymethylene, 120 ml of ethanol and 0.4 ml of concentrated HCl are heated under reflux for 4 to 5 hours. The product is allowed to crystallize, then filtered and washed with alcohol. It is dried and recrystallized from methanol containing 10% H2O.
There is thus obtained 60 g of a white crystalline powder soluble in water. Yield: 66%. Melting point: 160°C.

Therapeutic Function

Antitussive

Eprazinone dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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10402-53-6, Eprazinone dihydrochlorideRelated Search:

Eprazinone Methyl acetate Ethoxyamine hydrochloride Ipriflavone Ethoxyethyne METSULFURON METHYL Ethoxyquin Kresoxim-methyl DIETHOXYMETHANE Tribenuron methyl Piperazine Thiophanate-methyl Methyl salicylate Dihydrochloride Methyl Methyl bromide 1-(3-PHENYLPROPYL)PIPERAZINE 1-(2-PHENYLETHYL)PIPERAZINE

  • EPRAZINONE HYDROCHLORIDE
  • 3-[4-(beta-ethoxyphenethyl)-1-piperazinyl]-2-methylpropiophenone dihydrochloride
  • 1-Propanone, 3-[4-(2-ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-, dihydrochloride
  • 746CE
  • Eftapan
  • Mucitux
  • NSC 317935
  • Propiophenone, 3-[4-(β-ethoxyphenethyl)-1-piperazinyl]-2-methyl-, dihydrochloride (8CI)
  • Resplen
  • 1-(2-Benzoylpropyl)-4-(2-ethoxy-2-phenylethyl)piperazine dihydrochloride
  • Eprazinone 2HCl
  • 1-Propanone, 3-[4-(2-ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-, hydrochloride (1:2)
  • 3-[4-(2-Ethoxy-2-phenylethyl)piperazin-1-yl]-2-methyl-1-phenylpropan-1-one dihydrochloride
  • Eprazinone dihydrochloride
  • Rozuplen
  • Eprazinone diHCl
  • 3-[4-(β-ethoxyphenethyl)-1-piperazinyl]-2-Methylpropiophenone dihydrochloride
  • Eprazinone 2hydrochloride
  • -2-methyl-1-phenylpropan-1-one dihydrochloride
  • 3-(4-(2-Ethoxy-2-phenylethyl)
  • 3-[4-(β-ethoxyphenethyl)-1-piperazinyl]-2-methylpropiopheno...
  • Eprazinone DihydrochlorideQ: What is Eprazinone Dihydrochloride Q: What is the CAS Number of Eprazinone Dihydrochloride Q: What is the storage condition of Eprazinone Dihydrochloride Q: What are the applications of Eprazinone Dihydrochloride
  • 10402-53-6
  • C24H32N2O22HCl
  • C24H34N2O2Cl2
  • C24H34Cl2N2O2
  • Inhibitors