METHYL 3-METHOXY-4-METHYLBENZOATE

Preparation

Product Name: METHYL 3-METHOXY-4-METHYLBENZOATE
CAS No.: 3556-83-0
Chemical Name: METHYL 3-METHOXY-4-METHYLBENZOATE
Synonyms: METHYL 4-METHYL-M-ANISATE;METHYL 3-METHOXY-P-TOLUATE;METHYL 3-METHOXY-4-METHYLBENZOATE;4-METHYL-M-ANISIC ACID METHYL ESTER;Methyl3-Methoxy-4-methylbenzoate>3-METHOXY-P-TOLUIC ACID METHYL ESTER;Methyl 4-methyl-3-(methyloxy)benzoate;Methyl 3-methoxy-4-methylbenzoate, 98+%;3-Methoxy-4-methylbenzoate methyl ester;3-Methoxy-4-methyl-benzoesuremethylester
CBNumber: CB9372636
Molecular Formula: C10H12O3
Formula Weight: 180.2
MOL File: 3556-83-0.mol

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METHYL 3-METHOXY-4-METHYLBENZOATE Property

Melting point:: 50-54 °C (lit.)
Boiling point:: 119-120°C 1mm
Density: 1.075±0.06 g/cm3(Predicted)
refractive index: 1.5295
Flash point:: >230 °F
form: powder to crystal
color: White to Almost white
BRN: 1948339
CAS DataBase Reference: 3556-83-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 1
HS Code: 29189900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 528781
Product name: Methyl 3-methoxy-4-methylbenzoate
Purity: 96%
Packaging: 25g
Price: $885
Updated: 2023/06/20

TCI Chemical

Product number: M1427
Product name: Methyl 3-Methoxy-4-methylbenzoate
Purity: >98.0%(GC)
Packaging: 5g
Price: $40
Updated: 2024/03/01

TCI Chemical

Product number: M1427
Product name: Methyl 3-Methoxy-4-methylbenzoate
Purity: >98.0%(GC)
Packaging: 25g
Price: $132
Updated: 2024/03/01

Alfa Aesar

Product number: B22695
Product name: Methyl 3-methoxy-4-methylbenzoate, 98%
Packaging: 5g
Price: $100.65
Updated: 2024/03/01

Alfa Aesar

Product number: B22695
Product name: Methyl 3-methoxy-4-methylbenzoate, 98%
Packaging: 1g
Price: $39.5
Updated: 2021/12/16

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METHYL 3-METHOXY-4-METHYLBENZOATE Chemical Properties,Usage,Production

Preparation

Methyl 3-methoxy-4-methylbenzoate is synthesized by the following steps:A mixture of methyl 3-hydroxy-4-methylbenzoate 36 (25 g, 0.151 mol), Me2SO4 (28.3 ml, 0.386 mol), anhydrous K2CO3 (103.5 g, 0.75 mol) was refluxed in acetone for 2 hours. K2CO3 was filtered off, washed thoroughly with acetone. The filtrates were combined and concentrated, the residue was redissolved in EtOAc washed with water, dried (anhydrous Na2SO4), filtered and concentrated in vacuo to furnish a white solid (19.52 g). Yield : 72%.

Chemical Properties

White low melting solid

Uses

Methyl 3-Methoxy-4-methylbenzoate has been used as a reactant in the preparation of an antimalaria drug that consists of the 4-aminoquinoline pharmacophore of chloroquine with clotrimazole-based antimalarials.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 33, p. 1771, 1990 DOI: 10.1021/jm00168a036

General Description

Methyl 3-methoxy-4-methylbenzoate can be prepared by reacting diazomethane with 3-methoxy-4-methylbenzoic acid in ether.

METHYL 3-METHOXY-4-METHYLBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 3-METHOXY-4-METHYLBENZOATE Suppliers

Americas 1 China 129 Europe 3 France 1 Germany 3 India 9 Japan 2 Switzerland 1 United Kingdom 9 United States 20 Global 178

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View Lastest Price from METHYL 3-METHOXY-4-METHYLBENZOATE manufacturers

Career Henan Chemical Co

Product: Methyl 3-methoxy-4-methylbenzoate 3556-83-0
Price: US $1.00/KG
Min. Order: 1g
Purity: 98%
Supply Ability: 200kgs
Release date: 2020-01-09

3556-83-0, METHYL 3-METHOXY-4-METHYLBENZOATERelated Search:

Methyl vanillate Methyl 3-methyl-5-(trifluoromethyl)benzoate Methyl 3-methyl-4-nitrobenzoate Methyl 3-Methyl-5-nitrobenzoate METHYL 3-METHOXYPHENYLACETATE Methyl 3-methoxy-4-nitrobenzoate Methyl 3-methyl-2-nitrobenzoate 2,4,5-Trifluoro-3-methoxy-benzoic acid methyl ester 3-Methoxy-2,4,5-trifluorobenzoic acid Methyl 3-methyl-4-oxopentanoate METHYL 3-METHOXY-2-NITROBENZOATE Methyl 3-methoxy-2-methylbenzoate METHYL 5-BROMO-2-METHOXY-3-METHYLBENZENECARBOXYLATE METHYL 4-(BROMOMETHYL)-3-METHOXYBENZOATE METHYL 2-METHOXY-4-METHYLBENZOATE METHYL 3,5-DIBROMO-2,4-DIMETHOXY-6-METHYLBENZOATE 4-Methoxy-3-methylbenzoic acid 3-Methoxy-4-methylbenzoic acid

METHYL 3-METHOXY-P-TOLUATE

METHYL 3-METHOXY-4-METHYLBENZOATE

3-Methoxy-4-methyl-benzoesuremethylester

4-METHOXY-3-METHYLBENZOIC ACID METHYL ESTER

Methyl 3-methoxy-4-methylbenzoate, 98+%

Benzoic acid, 3-Methoxy-4-Methyl-, Methyl ester

3-Methoxy-4-methylbenzoic Acid Methyl Ester 3-Methoxy-p-toluic Acid Methyl Ester 4-Methyl-m-anisic Acid Methyl Ester Methyl 3-Methoxy-p-toluate Methyl 4-Methyl-m-anisate

Methyl 4-methyl-3-(methyloxy)benzoate

4-METHYL-M-ANISIC ACID METHYL ESTER

METHYL 4-METHYL-M-ANISATE

3-METHOXY-4-METHYLBENZOIC ACID METHYL ESTER

3-METHOXY-P-TOLUIC ACID METHYL ESTER

Methyl3-Methoxy-4-methylbenzoate&gt

3-Methoxy-4-Methylbenzoic Acid Methyl Easter

3-Methoxy-4-methylbenzoate methyl ester

3556-83-0

CH3OC6H3CH3CO2CH3

Organic Building Blocks

Esters

Building Blocks

Carbonyl Compounds

C10 to C11

Carbonyl Compounds

Esters

Acids & Esters

Anisoles, Alkyloxy Compounds & Phenylacetates

Aromatic Esters

C10 to C11