ChemicalBook > CAS DataBase List > (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE

Product Name: (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE
CAS No.: 59474-01-0
Chemical Name: (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE
Synonyms: XI-011;NSC 146109;NSC 146109 HYDROCHLORIDE;NSC 146109 (HYDROCHLORIDE);XI-011;XI-011 (NSC 146109 hydrochloride);NSC 146109 hydrochloride, 10 mM in DMSO;NSC 146109 hydrochloride, Cell-permeable p53 activator;S-(10-Methylanthracen-9-yl)methyl Isothiourea Hydrochloride;(10-Methylanthracen-9-yl)methyl Carbamimidothiote Hydrochloride;(10-Methylanthracen-9-yl)methyl carbamimidothioate hydrochloride
CBNumber: CB9385498
Molecular Formula: C17H17ClN2S
Formula Weight: 316.85
MOL File: 59474-01-0.mol

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(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Property

storage temp.: Desiccate at RT
solubility: Soluble to 10 mM in ethanol and to 100 mM in DMSO
form: Powder
color: White to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2570
Product name: NSC 146109 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $60.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML2570
Product name: NSC 146109 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $207
Updated: 2025/07/31

Cayman Chemical

Product number: 16430
Product name: NSC 146109 (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 16430
Product name: NSC 146109 (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $138
Updated: 2024/03/01

Cayman Chemical

Product number: 16430
Product name: NSC 146109 (hydrochloride)
Purity: ≥98%
Packaging: 25mg
Price: $324
Updated: 2024/03/01

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(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

This molecule inhibits MDMX expression in breast cancer cells through activating p53 resulting in apoptosis in cancer cells.

Biological Activity

Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay.

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Suppliers

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59474-01-0, (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDERelated Search:

8-HYDROXY-7-(6-SULFO-2-NAPHTHYLAZO)-5-QUINOLINESULFONIC ACID DISODIUM SALT 2-Amino-5-methylphenyl)phosphonic Acid SID 487795 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- NSC228155 3-((Furan-2-ylmethyl)imino]-N,N-dimethyl-3H-1,2,4-dithiazol-5-amine Hydrobromide (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE

NSC 146109 HYDROCHLORIDE

(10-Methylanthracen-9-yl)methyl Carbamimidothiote Hydrochloride

(10-Methylanthracen-9-yl)methyl carbamimidothioate hydrochloride

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE

(10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride

NSC 146109

NSC 146109 (HYDROCHLORIDE);XI-011

XI-011

S-(10-Methylanthracen-9-yl)methyl Isothiourea Hydrochloride

XI-011 (NSC 146109 hydrochloride)

NSC-146109,proapoptotic,breast cancer,NSC 146109 hydrochloride,inhibit,MDM-2/p53,NSC146109,NSC 146109,p53,Inhibitor,Apoptosis

NSC 146109 hydrochloride, Cell-permeable p53 activator

NSC 146109 hydrochloride, 10 mM in DMSO

59474-01-0

C17H16N2SHCl

Caspases/Apoptosis

Cell Cycle Regulation