ChemicalBook > CAS DataBase List > (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE

Product Name
(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE
CAS No.
59474-01-0
Chemical Name
(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE
Synonyms
XI-011;NSC 146109;NSC 146109 HYDROCHLORIDE;NSC 146109 (HYDROCHLORIDE);XI-011;XI-011 (NSC 146109 hydrochloride);S-(10-Methylanthracen-9-yl)methyl Isothiourea Hydrochloride;(10-Methylanthracen-9-yl)methyl Carbamimidothiote Hydrochloride;(10-Methylanthracen-9-yl)methyl carbamimidothioate hydrochloride;(10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride;(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE
CBNumber
CB9385498
Molecular Formula
C17H17ClN2S
Formula Weight
316.85
MOL File
59474-01-0.mol
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(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Property

storage temp. 
Desiccate at RT
solubility 
Soluble to 10 mM in ethanol and to 100 mM in DMSO
form 
Powder
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2570
Product name
NSC 146109 hydrochloride
Purity
≥98% (HPLC)
Packaging
5MG
Price
$71.3
Updated
2023/06/20
Sigma-Aldrich
Product number
SML2570
Product name
NSC 146109 hydrochloride
Purity
≥98% (HPLC)
Packaging
25MG
Price
$231
Updated
2023/06/20
Cayman Chemical
Product number
16430
Product name
NSC 146109 (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
16430
Product name
NSC 146109 (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$138
Updated
2024/03/01
Cayman Chemical
Product number
16430
Product name
NSC 146109 (hydrochloride)
Purity
≥98%
Packaging
25mg
Price
$324
Updated
2024/03/01
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(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

This molecule inhibits MDMX expression in breast cancer cells through activating p53 resulting in apoptosis in cancer cells.

Biological Activity

Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay.

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Suppliers

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59474-01-0, (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDERelated Search:

8-HYDROXY-7-(6-SULFO-2-NAPHTHYLAZO)-5-QUINOLINESULFONIC ACID DISODIUM SALT 2-Amino-5-methylphenyl)phosphonic Acid SID 487795 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- NSC228155 3-((Furan-2-ylmethyl)imino]-N,N-dimethyl-3H-1,2,4-dithiazol-5-amine Hydrobromide (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE

  • NSC 146109 HYDROCHLORIDE
  • (10-Methylanthracen-9-yl)methyl Carbamimidothiote Hydrochloride
  • (10-Methylanthracen-9-yl)methyl carbamimidothioate hydrochloride
  • (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE
  • (10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride
  • NSC 146109
  • NSC 146109 (HYDROCHLORIDE);XI-011
  • XI-011
  • S-(10-Methylanthracen-9-yl)methyl Isothiourea Hydrochloride
  • XI-011 (NSC 146109 hydrochloride)
  • NSC-146109,proapoptotic,breast cancer,NSC 146109 hydrochloride,inhibit,MDM-2/p53,NSC146109,NSC 146109,p53,Inhibitor,Apoptosis
  • 59474-01-0
  • C17H16N2SHCl
  • Caspases/Apoptosis
  • Cell Cycle Regulation