ChemicalBook > CAS DataBase List > Tosyl cyanide

Tosyl cyanide

Product Name
Tosyl cyanide
CAS No.
19158-51-1
Chemical Name
Tosyl cyanide
Synonyms
4-Methylbenzenesulfonyl cyanide;P-TOLUENESULFONYL CYANIDE;4-Methylbenzene-1-sulfonyl cyanide;osyl cyanide;TOSYL CYANIDE;p-Tosyl cyanide;Tosyl Cyanide (>90%);P-TOLYLSULFONYL CYANIDE;4-Toluenesulfonyl Cyanide;4-TolueenesulfonylCyanide
CBNumber
CB9387346
Molecular Formula
C8H7NO2S
Formula Weight
181.21
MOL File
19158-51-1.mol
More
Less

Tosyl cyanide Property

Melting point:
47-50 °C (lit.)
Boiling point:
105-106 °C/1 mmHg (lit.)
Density 
1.3055 (rough estimate)
refractive index 
1.5650 (estimate)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Sparingly), Ethyl Acetate
form 
crystalline solid
color 
White
BRN 
2048159
Stability:
Hygroscopic, Moisture Sensitive
CAS DataBase Reference
19158-51-1(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
C
Risk Statements 
20/21-34
Safety Statements 
26-27-28-36/37/39-45
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
F 
10-21
HazardClass 
8
PackingGroup 
III
HS Code 
2930909899
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
248835
Product name
p-Toluenesulfonyl cyanide
Purity
technical grade, 95%
Packaging
1g
Price
$86.5
Updated
2024/03/01
Sigma-Aldrich
Product number
248835
Product name
p-Toluenesulfonyl cyanide
Purity
technical grade, 95%
Packaging
5g
Price
$230
Updated
2024/03/01
TRC
Product number
T631000
Product name
TosylCyanide(>90%)
Packaging
25g
Price
$400
Updated
2021/12/16
AK Scientific
Product number
X2932
Product name
p-Toluenesulfonyl cyanide
Packaging
25g
Price
$480
Updated
2021/12/16
SynQuest Laboratories
Product number
8763-1-X2
Product name
Toluene-4-sulfonyl cyanide
Purity
97%
Packaging
25g
Price
$615
Updated
2021/12/16
More
Less

Tosyl cyanide Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

p-Toluenesulfonyl cyanide can be used in:

  • The preparation of polyfunctional nitriles.
  • Free-radical cyanation of B-alkylcatecholboranes.
  • The synthesis of 4-hyroxypyridines by hetero-Diels-Alder reaction with 1,3-bis-silyl enol ethers.

Uses

Tosyl cyanide is used in a free-radical cyanation of B-alkylcatecholboranes. Also used as a component in a hetero-Diels-Alder reaction with 1,3-bis-silyl enol ethers leading to 4-hyroxypyridines.

Synthesis Reference(s)

Tetrahedron Letters, 10, p. 3351, 1969 DOI: 10.1017/S0009838800024678

General Description

p-Toluenesulfonyl cyanide is an electron-deficient nitrile. It undergoes hetero-Diels-Alder reaction with silyl enol ether of cyclohexenone to yield hydrolytically sensitive [4+2] adduct. It also undergoes facile [2+3] cycloaddition reaction with azides to form 5-sulfonyl tetrazoles. p-Toluenesulfonyl cyanide also reacts with alcohols in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) or 1,4-diazabicyclo[2.2.2]octane (DABCO) to yield sulfinates.

Tosyl cyanide Preparation Products And Raw materials

Raw materials

Preparation Products

2-Azabicyclo[2.2.1]hept-5-en-3-one
More
Less

Tosyl cyanide Suppliers

Belgium 1 Canada 1 China 155 Europe 2 Germany 2 India 5 Switzerland 1 The Netherlands 1 United Kingdom 9 United States 23 Global 200
Zibo Qichuan Run Chemical Co., Ltd.
Tel
18553314927
Fax
0533-6312088
Email
77402664@qq.com
Country
China
ProdList
18
Advantage
58
Jiaxing Zhejia Biotechnology Co., LTD
Tel
0573-85609002
Email
zhejia01@163.com
Country
China
ProdList
8870
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2963
Advantage
65
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Beijing Taiya Jie Technology Development Co., Ltd.
Tel
021-33690831-8001 13552411790
Fax
021-33690831
Email
postmaster@tyjchem.cn
Country
China
ProdList
1541
Advantage
55
UHN Shanghai Research & Development Co., Ltd.
Tel
021-58958002 18930822973
Fax
+86 (21) 5895-8628
Email
SALES@UHNSHANGHAI.COM
Country
China
ProdList
977
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Shanghai Huikai Chemical Technology Co., Ltd.
Tel
021-61995394 18916691159
Email
chemicalsea@163.com
Country
China
ProdList
1972
Advantage
58
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3583
Advantage
55
Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
15523000485
Email
xingcanyaoye@sina.com
Country
China
ProdList
1686
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
7295
Advantage
60
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10276
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11481
Advantage
59
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Watson Biotechnology Co.,Ltd
Tel
027-59207879 1972026995 18140587686
Fax
QQ：1972026995
Email
sales@3600chem.com
Country
China
ProdList
4668
Advantage
55
Struchem Co., Ltd.
Tel
0512-0512-63009836 15365350169
Fax
0512-63006936
Email
helen@struchem.com
Country
China
ProdList
3984
Advantage
60
Shanghai Send Pharmaceutical Technology Co., Ltd.
Tel
021-58088081 Q3252066219
Fax
QQ3382968513
Email
danping@shsendpharm.com
Country
China
ProdList
3130
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
Chengdu DingDang Pharmaceutical Co., Ltd.
Tel
028-86040038 13980902949;
Fax
028-85149890
Email
market@dingdangchem.com
Country
China
ProdList
1843
Advantage
55
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9021
Advantage
60
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13320
Advantage
58
Shijiazhuang Yesheng Chemical Technology Co., Ltd
Tel
0311-68030586 18031147013
Fax
0311-68030586
Email
yeshengchemical@163.com
Country
China
ProdList
2688
Advantage
58
Wuhan Wsem Biological Co., Ltd.
Tel
027-83778876 13667159345
Fax
027-83778876
Email
13667159345@163.com
Country
China
ProdList
1990
Advantage
55
Wuhai Shuou Technology Co., Ltd.
Tel
17792809151
Fax
18872220797
Email
2355916837@ycphar.com
Country
China
ProdList
6133
Advantage
55
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7570
Advantage
55
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
10007
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19800
Advantage
60
Jiaxing Deyi Chemical Co., Ltd.
Tel
0573-86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8025
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718 +86-13336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29791
Advantage
60
Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15394
Advantage
58
Nanjing NingFan Pharm-Tech CO. LTD.
Tel
17368696818
Country
China
ProdList
1984
Advantage
58
More
Less

View Lastest Price from Tosyl cyanide manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tosyl cyanide 19158-51-1
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-17
Hebei Weibang Biotechnology Co., Ltd
Product
Tosyl cyanide 19158-51-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-10-25
Zibo Hangyu Biotechnology Development Co., Ltd
Product
Tosyl cyanide 19158-51-1
Price
US $70.00-700.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-09

19158-51-1, Tosyl cyanideRelated Search:

Chloral hydrate TOLBUTAMIDE 4-Methylbenzenesulfonhydrazide p-Toluenesulfonamide Copper(I) Cyanide Tosyl chloride Tosyl azide P-Toluenesulfonic anhydride p-Toluenesulfonic acid monohydrate Ethyl p-toluenesulfonate Methyl p-toluenesulfonate P-TOLUENESULFONIC ACID N-BUTYL ESTER HYDROGEN CYANIDE (4-Methylthio)toluene METHYL PHENYL SULFOXIDE 1-METHYL-4-(METHYLSULFINYL)BENZENE Toluene Methyl thiocyanate

  • p-tolylsulfonylforMonitrile
  • p-Tosyl cyanide
  • Toluene-4-sulfonyl cyanide 98%
  • p-Toluenesulfonyl cyanide technical grade, 95%
  • Toluene-4-sulphonylcyanide,tech
  • P-TOLYLSULFONYL CYANIDE
  • p-toluenesulphonyl cyanide
  • P-TOLUENESULFONYL CYANIDE
  • TOSYL CYANIDE
  • 4-Toluenesulfonyl Cyanide
  • P-TOLUENESULFONYL CYANIDE, TECH., APPROX . 95%
  • 4-TolueenesulfonylCyanide
  • P-TOLUENE SULFONYL CYANIDE(P-TOLYLSULFNYL CYANIDE)
  • 4-TOLUENESULFONYLCYANIDE, 95+%
  • toluene-4-sulfonyl cyanide
  • p-Tolylsulfonyl cyanide, Tosyl cyanide
  • Benzenesulfonylcyanide, 4-Methyl-
  • Toluene-4-sulphonyl cyanide
  • Tosyl cyanide, 4-Methylbenzenesulphonyl cyanide
  • 4-Methylbenzenesulfonyl cyanide
  • 4-Methylbenzene-1-sulfonyl cyanide
  • Tosyl cyanide, 4-Methylbenzenesulphonyl cyanide, 4-(Cyanosulphonyl)toluene
  • <I>p</I>-Toluenesulfonyl cyanide
  • (4-methylphenyl)sulfonylformonitrile
  • Tosyl cyanide ISO 9001：2015 REACH
  • Tosyl Cyanide (>90%)
  • osyl cyanide
  • 19158-51-1
  • Cyanides/Nitriles
  • Organic Building Blocks
  • Nitrogen Compounds
  • Building Blocks
  • C8 to C9
  • Building Blocks
  • C8 to C9
  • Chemical Synthesis
  • Cyanides/Nitriles
  • Nitrogen Compounds
  • Organic Building Blocks