4-Bromophenethyl alcohol
- Product Name
- 4-Bromophenethyl alcohol
- CAS No.
- 4654-39-1
- Chemical Name
- 4-Bromophenethyl alcohol
- Synonyms
- 2-(4-BROMOPHENYL)ETHAN-1-OL;2-(4-BROMOPHENYL)ETHANOL;AURORA KA-6987;4-BroMophenethyl;4-BroMophenethanol;4-Bromophenylethanol;4-BROMOBENZENE ETHANOL;4-Bromophenethyl alcoho;ThebroMo benzeneethanol;p-Bromophenethyl alcohol
- CBNumber
- CB9398078
- Molecular Formula
- C8H9BrO
- Formula Weight
- 201.06
- MOL File
- 4654-39-1.mol
4-Bromophenethyl alcohol Property
- Melting point:
- 36-38 °C(lit.)
- Boiling point:
- 138 °C/9 mmHg (lit.)
- Density
- 1.436 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.573(lit.)
- Flash point:
- 146 °F
- storage temp.
- Sealed in dry,Room Temperature
- form
- Liquid
- pka
- 14.79±0.10(Predicted)
- color
- Clear colorless to light yellow
- BRN
- 2079929
- InChI
- InChI=1S/C8H9BrO/c9-8-3-1-7(2-4-8)5-6-10/h1-4,10H,5-6H2
- InChIKey
- PMOSJSPFNDUAFY-UHFFFAOYSA-N
- SMILES
- C1(CCO)=CC=C(Br)C=C1
- CAS DataBase Reference
- 4654-39-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzeneethanol, 4-bromo-(4654-39-1)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P330Rinse mouth.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
N-Bromosuccinimide Price
- Product number
- 183431
- Product name
- 4-Bromophenethyl alcohol
- Purity
- 99%
- Packaging
- 1g
- Price
- $35.62
- Updated
- 2025/07/31
- Product number
- 183431
- Product name
- 4-Bromophenethyl alcohol
- Purity
- 99%
- Packaging
- 10g
- Price
- $167.2
- Updated
- 2025/07/31
- Product number
- B1918
- Product name
- 2-(4-Bromophenyl)ethyl Alcohol
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $48
- Updated
- 2025/07/31
- Product number
- B1918
- Product name
- 2-(4-Bromophenyl)ethyl Alcohol
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $187
- Updated
- 2025/07/31
- Product number
- B698240
- Product name
- 2-(4-Bromophenyl)ethanol
- Packaging
- 2.5g
- Price
- $65
- Updated
- 2021/12/16
4-Bromophenethyl alcohol Chemical Properties,Usage,Production
Chemical Properties
CLEAR COLOURLESS TO LIGHT YELLOW LIQUID
Uses
4-Bromophenethyl alcohol was used in the synthesis of 4-(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenethoxy)quinazoline.
Synthesis
41841-16-1
4654-39-1
General procedure for the synthesis of 4-bromophenylethanol from methyl 4-bromophenylacetate: Methyl 4-bromophenylacetate (6 g, 26.2 mmol, 1.0 eq.) was dissolved in tetrahydrofuran (THF, 100 mL) and the solution was cooled to 0 °C. Lithium borohydride (LiBH4, 2M solution in THF, 1.41 g, 52.4 mmol, 2.0 eq.) was slowly added dropwise at 0 °C. After the dropwise addition, the reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the reaction was quenched with water and extracted with ethyl acetate (EtOAc). The organic layers were combined, washed with saturated saline, dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford the target product 4-bromophenethyl alcohol (4.5 g, 85.5% yield). The product was detected by LCMS, m/z: 204.8 [M + H]+. 1H NMR (400 MHz, DMSO-d6) δ 7.56-7.35 (m, 2H), 7.27-7.07 (m, 2H), 4.67 (t, J = 5.2 Hz, 1H), 3.58 (td, J = 6.8,5.4 Hz, 2H), 2.69 (t. J = 6.9Hz, 2H).
References
[1] Journal of Medicinal Chemistry, 2012, vol. 55, # 11, p. 5627 - 5631
[2] Patent: WO2015/66413, 2015, A1. Location in patent: Page/Page column 164; 165
[3] Chemistry - A European Journal, 2015, vol. 21, # 42, p. 14737 - 14741
[4] Advanced Synthesis and Catalysis, 2012, vol. 354, # 10, p. 1879 - 1884
[5] Synthesis, 2011, # 18, p. 2935 - 2940
4-Bromophenethyl alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
4-Bromophenethyl alcohol Suppliers
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- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
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- Country
- Americas
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View Lastest Price from 4-Bromophenethyl alcohol manufacturers
- Product
- 4-Bromophenethyl alcohol 4654-39-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 2000
- Release date
- 2025-09-03
- Product
- 4-Bromophenethylalcohol 4654-39-1
- Price
- US $1.00-1.50/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100000KG
- Release date
- 2024-07-31
- Product
- 4-Bromophenethyl alcohol 4654-39-1
- Price
- US $1.00-1.50/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100000KG
- Release date
- 2024-07-30