(MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE)

Description Source Background

Product Name: (MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE)
CAS No.: 75217-63-9
Chemical Name: (MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE)
Synonyms: GLUCAGON, HUMAN;GLUCAGON PEPTIDE;GLUCAGON, HUMAN/RAT;GLUCAGON (1-29), HUMAN;glucagon, Met-sulfoxide(27)-;HSQGTFTSDYSKYLDSRRAQDFVQWLMNT;GLUCAGON HUMAN, BOVINE, PORCINE;GLUCAGON (1-29), BOVINE, HUMAN, PORCINE;GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE);Glucagon (swine), 27-(L-methionine S-oxide)-
CBNumber: CB9401440
Molecular Formula: C153H225N43O50S
Formula Weight: 3498.75
MOL File: 75217-63-9.mol

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(MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE) Property

Density: 1.54±0.1 g/cm3(Predicted)
storage temp.: -20°C
Sequence: His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-{Met(O)}-Asn-Thr

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 05-23-2700
Product name: Glucagon, Human
Purity: Synthetic, human glucagon. Peptide hormone secreted by pancreatic α-cells. An important hyperglycemic agent.
Packaging: .1mg
Price: $138
Updated: 2025/07/31

Sigma-Aldrich

Product number: 05-23-2700
Product name: Glucagon, Human
Purity: Synthetic, human glucagon. Peptide hormone secreted by pancreatic α-cells. An important hyperglycemic agent.
Packaging: .5mg
Price: $275
Updated: 2025/07/31

Biorbyt Ltd

Product number: orb72744
Product name: Glucagon peptide
Packaging: 0.5mg
Price: $280.5
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb216626
Product name: Glucagon peptide
Purity: > 95%
Packaging: 1mg
Price: $302.6
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb103943
Product name: Glucagon peptide
Purity: Greater than 98 % purified
Packaging: 0.5mg
Price: $365.5
Updated: 2021/12/16

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(MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE) Chemical Properties,Usage,Production

Uses

(Met(O)27)-Glucagon (1-29) (human, rat, porcine) is a modified glucagon. (Met(O)27)-Glucagon (1-29) (human, rat, porcine) has the same maximum glucose-synthesizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor[1].

Description

Glucagon Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 29 amino acids and having a molecular mass of 3483 Dalton.
The Glucagon is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

Glucagon is an important hormone involved in carbohydrate metabolism. The hormone is synthesized and secreted from alpha cells (a-cells) of the islets of Langerhans, which are located in the endocrine portion of the pancreas. Glucagon is released when the glucose level in the blood is low (hypoglycemia), causing the liver to convert stored glycogen into glucose and release it into the bloodstream. The action of glucagon is thus opposite to that of insulin, which instructs the body's cells to take in glucose from the blood in times of satiation.
Glucagon is beneficial for the culture of some cell types. It has been used in some biochemical regulation studies of glycogenolysis in hepatocytes. It has been also been found to induce DNA replication in primary cultures of adult rat hepatocytes when used in combinations with EGF and Insulin. Glucagon increases the blood glucose concentration by promoting rapid breakdown of liver glycogen, and also acts to relax smooth muscle such as the gastrointestinal tract.

References

[1] Nooijen WJ, et al. Immunogenicity and bioactivity of glucagon, modified at methionine-27. Horm Metab Res. 1979 Aug;11(8):459-63. DOI:10.1055/s-0028-1092761

(MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE) Preparation Products And Raw materials

Raw materials

Preparation Products

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(MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE) Suppliers

China 81 Europe 2 France 1 Germany 2 India 1 Japan 2 Switzerland 1 The Netherlands 1 United Kingdom 2 United States 13 Global 106

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Creative Peptides

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Nanjing Leon Biological Technology Co., Ltd.

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75217-63-9, (MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE)Related Search:

Glucagon L-Threonine, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-2-methylalanyl-L-alanyl-L-arginyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-valyl-L-lysyl-L-tryptophyl-L-leucyl-L-α-glutamy... glucagon-like peptide 1 GLUCAGON HYDROCHLORIDE(HUMAN) GLP-1（Glucagon-like peptide-1）(7-36) GIP (HUMAN) GLUCAGON-37 (HUMAN, MOUSE, RAT) H-HIS-ASP-GLU-PHE-GLU-ARG-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-NH2 GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN GLP-1 Uric acid H-ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR-OH (MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE) Mazdutide Utreglutide H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-TyrLeu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-LeuVal-Lys-Gly-Arg-Lys(biotinyl)-NH2

glucagon, Met-sulfoxide(27)-

(MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE)

GLUCAGON, HUMAN

GLUCAGON HUMAN, BOVINE, PORCINE

GLUCAGON, HUMAN/RAT

GLUCAGON (1-29), BOVINE, HUMAN, PORCINE

GLUCAGON (1-29), HUMAN

GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE)

GLUCAGON PEPTIDE

HSQGTFTSDYSKYLDSRRAQDFVQWLMNT

H-HIS-SER-GLN-GLY-THR-PHE-THR-SER-ASP-TYR-SER-LYS-TYR-LEU-ASP-SER-ARG-ARG-ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET(O)-ASN-THR-OH

HIS-SER-GLN-GLY-THR-PHE-THR-SER-ASP-TYR-SER-LYS-TYR-LEU-ASP-SER-ARG-ARG-ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR

(Met(O)27)-Glucagon (1-29) (human, rat, porcine)

ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR: AQDFVQWLMNT

Glucagon (swine), 27-(L-methionine S-oxide)-

(Met(O)27)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt

(MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE) USP/EP/BP

Glucagon(swine),27-[(2S)-2-amino-4-(methylsulfinyl)butanoic acid]-

(Met(O)??)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt

Glucagon Impurity 8 Tetratrifluoroacetate Met(O) 27 Glucagon)

(Met(O))-Glucagon (1-29)(Human, bovine, porcine)

75217-63-9

C153H225N43O49S1

C153H225N43O50S

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