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Trimeprazine tartrate

Product Name
Trimeprazine tartrate
CAS No.
4330-99-8
Chemical Name
Trimeprazine tartrate
Synonyms
temaril;repeltin;panectyl;vanectyl;vallergan;theralene;NSC 17475;Temaril 16;Alimernazine;N,N,β-TriMethyl-
CBNumber
CB9407912
Molecular Formula
C22H28N2O6S
Formula Weight
448.53
MOL File
4330-99-8.mol
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Trimeprazine tartrate Property

Melting point:
153-155°C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml; PBS (pH 7.2): insol
form 
Solid
color 
White to Almost white
Merck 
14,9704
InChIKey
ZEEPCWVFSHMOPI-MVELKYERNA-N
SMILES
C(N1C2=CC=CC=C2SC2C=CC=CC1=2)C(C)CN(C)C.[C@H](O)(C(=O)O)[C@@H](O)C(=O)O |&1:21,26,r|
CAS DataBase Reference
4330-99-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
36
RIDADR 
3249
WGK Germany 
3
RTECS 
SO6475000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2934302700
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001583
Product name
Alimemazine hemitartrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
15 mg
Price
$118
Updated
2025/07/31
Sigma-Aldrich
Product number
Y0001581
Product name
Alimemazine for system suitability
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
5 mg
Price
$153
Updated
2025/07/31
Sigma-Aldrich
Product number
PHR1749
Product name
Trimeprazine hemi-(+)-tartrate salt
Packaging
1g
Price
$239
Updated
2025/07/31
Sigma-Aldrich
Product number
BP415
Product name
Alimemazine tartrate
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100MG
Price
$268
Updated
2025/07/31
Sigma-Aldrich
Product number
1689001
Product name
Trimeprazine tartrate
Packaging
200mg
Price
$425
Updated
2025/07/31
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Trimeprazine tartrate Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Uses

Antipruritic. Antibacterial, antimicrobial agent

brand name

Temaril (Allergan).

General Description

Trimeprazine tartrate, (±)10-[3-(dimethylamino)-2-methylpropyl] phenothiazine tartrate(Temaril), occurs as a white to off-white crystalline powderthat is freely soluble in water and soluble in alcohol. Its antihistaminicaction is reported to be from 1.5 to 5 times thatof promethazine. Clinical studies have shown it has a pronouncedantipruritic action that may be unrelated to itshistamine-antagonizing properties.

in vivo

Alimemazine hemitartrate (10 mg/kg, intraperitoneal injection, once a day for 3 weeks) promotes mouse β-cell growth[2].
Alimemazine hemitartrate (10 mg/kg, intraperitoneal injection, once a day for 22 days) synergistically reduces the progression of diabetes in NOD mice[2].
Alimemazine hemitartrate (10 mg/kg, intraperitoneal injection, once a day for 7 days) promotes the proliferation and survival of β-cells in normal mice, but has little effect on β-cell defects caused by IRS2 deficiency[2].
Alimemazine hemitartrate (10 mg/kg, oral gavage, two doses) does not reduce mouse lung virus titers[3].

Animal Model:Pdx1+/– mice[2]
Dosage:10 mg/kg, once a day for 3 weeks
Administration:Intraperitoneal injection (i.p.)
Result:Increased HOMA 2%B and normalized glucose tolerance in mice.
Animal Model:Irs2-/–mice[2]
Dosage:10 mg/kg, once a day for seven days
Administration:Intraperitoneal injection (i.p.)
Result:Did not restore the function of β cells, but promoted β cell growth and increased the area of β cells in normal mice.
Increased the concentration of IRS2 protein, had no effect on glucose tolerance in mice, and did not change the insulin sensitivity of mice.
Animal Model:SARS-CoV-2 multiplication in mice[3]
Dosage:10mg/kg, at 1 h prior to and 24 h after virus inoculation
Administration:i.g.
Result:Did not reduce lung virus titers.

IC 50

GPCR

Trimeprazine tartrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Trimeprazine tartrate Suppliers

Americas 1 Canada 2 CHINA 102 Czech Republic 1 Europe 1 Finland 1 France 5 Germany 3 India 14 Japan 1 Mexico 1 Monaco 2 Switzerland 2 United Kingdom 5 United States 23 Global 164
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View Lastest Price from Trimeprazine tartrate manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
Trimeprazine tartrate 4330-99-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-02-17
Career Henan Chemical Co
Product
Trimeprazine tartrate 4330-99-8
Price
US $3.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
200KG
Release date
2020-01-07

4330-99-8, Trimeprazine tartrate Related Search:

Triethanolamine Metoprolol tartrate Tylosin tartrate L(+)-Tartaric acid Bis(2-ethylhexyl)amine L-Antimony potassium tartrate Trimeprazine Propane Kitasamycin tartrate D-Tartaric acid D(-)-Tartaric acid Triallylamine L-Carnitine-L-tartrate Zolpidem tartrate Butanedioic acid,2,3-dihydroxy- (2R,3R)-, ammonium salt (1:) Promazine Phenothiazine Sodium tartrate

  • 10-(3-(dimethylamino)-2-methylpropyl)phenothiazinetartrate
  • 10-(3-(dimethylamino)-2-methylpropyl)-phenothiazintartrate(2:1)
  • panectyl
  • repeltin
  • temaril
  • theralene
  • vallergan
  • n,n,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine tartrate
  • vanectyl
  • alimemazine tartrate
  • trimeprazine hemi-(+)tartrate
  • HydroxystilbamidineIsothionate
  • 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)
  • 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (2:1)
  • NSC 17475
  • Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-, tartrate (2:1) (8CI)
  • Temaril 16
  • (3R,4R)-3,4-dihydroxyhexane-2,5-dione
  • TRIMEPRAZINE HEMI-(+)-TARTRATE SALT
  • TRIMEPRAZINE TARTRATE
  • TRIMEPRAZINE TARTRATE(R)(2:1)
  • Methylpromazine Tartrate
  • trimeprazine semitartrate
  • TriMeprazine HeMi-(+)-tartrate Salt, BP
  • Trimeprazine Tartrate (200 mg)
  • N,N,β-TriMethyl-
  • N,N,2-triMethyl-3-(10H-phenothiazin-10-yl)propan-1-aMine 2,3-dihydroxysuccinate
  • TriMeprazine Tartrate USP
  • Alimemazine for system suitability
  • Alimemazine hemitartrate
  • Alimernazine
  • Alimemazine Tartrate &gt
  • Alimemazine hemitartrate CRS
  • Trimeprazine tartrateQ: What is Trimeprazine tartrate Q: What is the CAS Number of Trimeprazine tartrate Q: What is the storage condition of Trimeprazine tartrate Q: What are the applications of Trimeprazine tartrate
  • Trimeprazine Tartrate (1689001)
  • Alimemazine Tartrate, ≥ 98.0%
  • Alimemazine hemitartrate, 10 mM in DMSO
  • Trimeprazine Tartrate 1.0 mg/ml in Methanol (as free base)
  • 4330-99-8
  • C36H44N4S2C4H6O6
  • C20H25N2O3S
  • C40H50N4O6S2
  • C4H6O62C18H22N2S
  • C24H32N2O4S
  • 2C18H22N2SC4H6O6
  • C18H22N2S2C4H6O6
  • C18H22N2S12C4H6O6
  • Amines
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds