2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone

Description Uses

Product Name: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
CAS No.: 106797-53-9
Chemical Name: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
Synonyms: Irgacure 2959;photoinitiator 2959;UV2959;darocur2959;HRcure-2959;2-hydroxy-1-(4-(2-hydroxyethoxy)phenyl)-2-methyl-1-propanone;1-Propanone, 2-hydroxy-1-4-(2-hydroxyethoxy)phenyl-2-methyl-;2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-Methylpropan-1-one;I2959;APi-2959
CBNumber: CB9415799
Molecular Formula: C12H16O4
Formula Weight: 224.25
MOL File: 106797-53-9.mol

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2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone Property

Melting point:: 88-90 °C(lit.)
Boiling point:: 405.0±25.0 °C(Predicted)
Density: 1.183±0.06 g/cm3(Predicted)
vapor pressure: 0Pa at 25℃
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 12.96±0.29(Predicted)
color: White to Light yellow
Water Solubility: 7.6g/L at 25℃
InChI: InChI=1S/C12H16O4/c1-12(2,15)11(14)9-3-5-10(6-4-9)16-8-7-13/h3-6,13,15H,7-8H2,1-2H3
InChIKey: GJKGAPPUXSSCFI-UHFFFAOYSA-N
SMILES: C(C1=CC=C(OCCO)C=C1)(=O)C(O)(C)C
LogP: 0.84 at 23℃
CAS DataBase Reference: 106797-53-9(CAS DataBase Reference)
EPA Substance Registry System: 1-Propanone, 2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl- (106797-53-9)

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Safety

Safety Statements: 24/25
WGK Germany: 2
RTECS: UC2976000
HS Code: 29145090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 410896
Product name: 2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone
Purity: 98%
Packaging: 10g
Price: $65.17
Updated: 2025/07/31

Sigma-Aldrich

Product number: 410896
Product name: 2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone
Purity: 98%
Packaging: 50g
Price: $223.25
Updated: 2025/07/31

TCI Chemical

Product number: H1361
Product name: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
Purity: >98.0%(HPLC)
Packaging: 5g
Price: $43
Updated: 2025/07/31

TCI Chemical

Product number: H1361
Product name: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
Purity: >98.0%(HPLC)
Packaging: 25g
Price: $128
Updated: 2025/07/31

TCI Chemical

Product number: H1361
Product name: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
Purity: >98.0%(HPLC)
Packaging: 100g
Price: $334
Updated: 2025/07/31

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2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone Chemical Properties,Usage,Production

Description

2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone(Photoinitiator 2959) has been tested for use in UV curing formulations on wood, metal, plastic and paper surfaces.It has lower volatility and odor compared to Irgacure 1173. Importantly, the reactive hydroxyl groups of it are easily grafted onto the polymer molecules, making it more convenient to process.

Uses

2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone is a photoinitiator allowed by the FDA certification system; it can be used in water-based photocuring systems, with high melting point, and can also be used in UV-curable powder coatings; it is a high-efficiency non-yellowing UV photoinitiator. UV polymerization of saturated prepolymerized systems.

Chemical Properties

Density 1.183 g/cm3, melting point 88-90°C (lit.), boiling point 405℃ at 760 mmH, flash point 155.8℃, refractive index .544, vapor pressure 2.75E-07 mmHg at 25℃.

Uses

2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone is used in the preparation of UV-VIS curable PEG hydrogels for biomedical applications with multi-functionality.

Definition

ChEBI: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone is an aromatic ketone.

Synthesis

159119-01-4

106797-53-9

The general procedure for the synthesis of photoinitiator 2959 from the compound (CAS:159119-01-4) was as follows: a 25 mL Schlenk reaction tube was taken and N-bromosuccinimide (NBS) 18 mg (0.1 mmol) was added sequentially as catalyst, 4'-(2-hydroxyethoxy)-2-methylpropiophenone 105 mg (0.5 mmol), and dimethyl sulfoxide (DMSO) 1 mL as oxidizing reagent and solvent. ), and dimethyl sulfoxide (DMSO) 1 mL as oxidizer, carbonylation reagent and solvent. The reaction mixture was stirred at 100 °C for 24 hours. Upon completion of the reaction, 15 mL of ethyl acetate and 3 mL of brine were added to the reaction mixture for extraction, which was then extracted three times with ethyl acetate. All organic phases were combined and purified by column chromatographic separation to give a final purity of 103 mg of 2-hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone in 92% yield.

References

[1] Organic Letters, 2015, vol. 17, # 4, p. 876 - 879
[2] Patent: CN104710256, 2017, B. Location in patent: Paragraph 0174-0177
[3] Angewandte Chemie - International Edition, 2014, vol. 53, # 2, p. 548 - 552
[4] Angew. Chem., 2014, vol. 53, # 2, p. 558 - 562,5
[5] Patent: CN107739303, 2018, A. Location in patent: Paragraph 0017

2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone Suppliers

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View Lastest Price from 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone 106797-53-9
Price: US $2.20-8.80/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons
Release date: 2025-07-08

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone/IHT-PI 659 106797-53-9
Price: US $0.00-0.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 98%min
Supply Ability: 1000KG
Release date: 2021-06-07

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone 106797-53-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10mt
Release date: 2024-11-05

106797-53-9, 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenoneRelated Search:

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α-Hydroxyketone（1113）

410896-10G

2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone

106797-53-9

1722-04-1

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