ChemicalBook > CAS DataBase List > Diethyl malate

Diethyl malate

Product Name
Diethyl malate
CAS No.
7554-12-3
Chemical Name
Diethyl malate
Synonyms
FEMA 2374;DIETHYL MALATE;ETHYL-DL-MALATE;DIETHYL DL-MALATE;Malic acid diethyl;DiethylDL-Malate>Diethyl hydroxysuccinate;Diethyl 2-hydroxysuccinate;DL-APPLE ACID DIETHYL ESTER;DL-MALIC ACID DIETHYL ESTER
CBNumber
CB9418215
Molecular Formula
C8H14O5
Formula Weight
190.19
MOL File
7554-12-3.mol
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Diethyl malate Property

Boiling point:
122-124 °C12 mm Hg(lit.)
Density 
1.128 g/mL at 25 °C(lit.)
refractive index 
1.4330 to 1.4360
FEMA 
2374 | DIETHYL MALATE
Flash point:
185 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Sparingly), Ethyl Acetate (Slightly)
pka
12.35±0.20(Predicted)
form 
clear liquid
color 
Colorless to Light yellow
Odor
at 100.00 %. brown sugar sweet wine fruity herbal
Odor Type
caramellic
JECFA Number
620
Dielectric constant
10.2(18℃)
LogP
0.23
EPA Substance Registry System
Butanedioic acid, hydroxy-, diethyl ester (7554-12-3)
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Safety

WGK Germany 
3
HS Code 
2918.19.9000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W237418
Product name
Diethyl malate
Purity
≥97%, FG
Packaging
sample
Price
$54.6
Updated
2024/03/01
Sigma-Aldrich
Product number
W237418
Product name
Diethyl malate
Purity
≥97%, FG
Packaging
1kg
Price
$349
Updated
2024/03/01
TCI Chemical
Product number
M0024
Product name
Diethyl DL-Malate
Purity
>98.0%(GC)
Packaging
25g
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
M0024
Product name
Diethyl DL-Malate
Purity
>98.0%(GC)
Packaging
500g
Price
$284
Updated
2024/03/01
Sigma-Aldrich
Product number
W237418
Product name
Diethyl malate
Purity
≥97%, FG
Packaging
100g
Price
$81.9
Updated
2024/03/01
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Diethyl malate Chemical Properties,Usage,Production

Chemical Properties

Diethyl malate has a fruity odor with a pleasant herbaceous undertone. It is an ester of dicarboxylic acid

Occurrence

It exhibits two optically active isomers in addition to the optically inactive form; the most common is the l-isomer; reported present in the cultures of certain fungi (Rhizopus). Reported found in raspberry, cognac, malt whiskey, cider, sherry, white, red, port, sparkling, rose, strawberry and bilberry wines

Uses

Diethyl DL-Malate is used as a reagent in the synthesis of dicarboxylic nitroxyalkylamides and nitroxyalkylimides as anti-ischemic agents.

Definition

ChEBI: Diethyl malate is a malate ester obtained by the formal condensation of the two carboxy groups of malic acid with two molecules of ethanol respectively. It has a role as a metabolite.

Preparation

The l-isomer can be prepared by esterification of the l-isomer of the acid with alcohol in the presence of HCl.

Synthesis Reference(s)

Synthesis, p. 138, 1982 DOI: 10.1055/s-1982-29718

Diethyl malate Preparation Products And Raw materials

Raw materials

Preparation Products

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Diethyl malate Suppliers

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View Lastest Price from Diethyl malate manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Diethyl DL-Malate 7554-12-3
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-01-17
Hebei Mojin Biotechnology Co., Ltd
Product
Diethyl malate 7554-12-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-22
Hebei Guanlang Biotechnology Co., Ltd.
Product
Diethyl malate 7554-12-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2023-03-27

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