L-ETHIONINE
- Product Name
- L-ETHIONINE
- CAS No.
- 13073-35-3
- Chemical Name
- L-ETHIONINE
- Synonyms
- H-ETH-OH;Nsc82393;L-ETHIONINE;l-butyricaci;L-Ethionine>L-ETHIONINE 98+%;L -ETHIONINE 99%;s-ethyl-homocystein;s-ethyl-l-homocystein;S-ethyl-L-homocysteine
- CBNumber
- CB9426830
- Molecular Formula
- C6H13NO2S
- Formula Weight
- 163.24
- MOL File
- 13073-35-3.mol
L-ETHIONINE Property
- Melting point:
- 280 °C (dec.)(lit.)
- alpha
- D24 +25.1°; D23 +20.1° (1N HCl) (Armstrong, Lewis)
- Density
- 1.085 (estimate)
- refractive index
- 22 ° (C=1, 1mol/L HCl)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- Aqueous Acid (Slightly), Water (Slightly)
- form
- solid
- Boiling point:
- 310.4±37.0 °C(Predicted)
- pka
- 2.23±0.10(Predicted)
- color
- White to Off-White
- Merck
- 14,3738
- CAS DataBase Reference
- 13073-35-3(CAS DataBase Reference)
- EPA Substance Registry System
- L-Ethionine (13073-35-3)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26
- WGK Germany
- 3
- RTECS
- ES6825300
- HS Code
- 2930.90.4950
- Hazardous Substances Data
- 13073-35-3(Hazardous Substances Data)
- Toxicity
- rat,LD,intraperitoneal,> 1gm/kg (1000mg/kg),LIVER: OTHER CHANGESLIVER: CHANGES IN LIVER WEIGHT,Acta Pathologica Japonica. Vol. 39, Pg. 281, 1989.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- E1260
- Product name
- L-Ethionine
- Purity
- ≥99% (TLC)
- Packaging
- 250mg
- Price
- $213
- Updated
- 2024/03/01
- Product number
- E1260
- Product name
- L-Ethionine
- Purity
- ≥99% (TLC)
- Packaging
- 1g
- Price
- $700
- Updated
- 2024/03/01
- Product number
- E0039
- Product name
- L-Ethionine
- Purity
- >98.0%(T)
- Packaging
- 100mg
- Price
- $71
- Updated
- 2024/03/01
- Product number
- E890435
- Product name
- L-Ethionine
- Packaging
- 500mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- E890435
- Product name
- L-Ethionine
- Packaging
- 5g
- Price
- $820
- Updated
- 2021/12/16
L-ETHIONINE Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
Ethionine-induced inhibition of protein synthesis and lowering of ATP level in the liver.
Definition
ChEBI: An S-ethylhomocysteine that has S-configuration at the chiral centre.
Biological Activity
An analog of methionine th at interferes with the normal methylation of DNA and other methylation pathways, and induces pancreatic toxicity and liver cancer. However, in animal studies, it has also been shown to act synergistically with methionine-depletion to block the growth and metastasis of methionine-dependent tumors.
Purification Methods
Likely impurities are N-acetyl-(R and S)-ethionine, S-methionine, and R-ethionine. Crystallise it from water by adding 4volumes of EtOH or 85% aqueous EtOH. It sublimes at 196-216o/0.3mm with 99.1% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Weiss & Stekol J Am Chem Soc 73 2399 1951, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2658, 2659 1961, Beilstein 4 IV 3194.]
L-ETHIONINE Preparation Products And Raw materials
Raw materials
Preparation Products
L-ETHIONINE Suppliers
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View Lastest Price from L-ETHIONINE manufacturers
- Product
- L-ethionine 13073-35-3
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- >98%
- Supply Ability
- 20 tons
- Release date
- 2020-02-10