ChemicalBook > CAS DataBase List > L-ETHIONINE

L-ETHIONINE

Product Name
L-ETHIONINE
CAS No.
13073-35-3
Chemical Name
L-ETHIONINE
Synonyms
H-ETH-OH;Nsc82393;L-ETHIONINE;l-butyricaci;L-Ethionine>L-ETHIONINE 98+%;L -ETHIONINE 99%;s-ethyl-homocystein;s-ethyl-l-homocystein;S-ethyl-L-homocysteine
CBNumber
CB9426830
Molecular Formula
C6H13NO2S
Formula Weight
163.24
MOL File
13073-35-3.mol
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L-ETHIONINE Property

Melting point:
280 °C (dec.)(lit.)
alpha 
D24 +25.1°; D23 +20.1° (1N HCl) (Armstrong, Lewis)
Density 
1.085 (estimate)
refractive index 
22 ° (C=1, 1mol/L HCl)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
Aqueous Acid (Slightly), Water (Slightly)
form 
solid
Boiling point:
310.4±37.0 °C(Predicted)
pka
2.23±0.10(Predicted)
color 
White to Off-White
Merck 
14,3738
CAS DataBase Reference
13073-35-3(CAS DataBase Reference)
EPA Substance Registry System
L-Ethionine (13073-35-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
RTECS 
ES6825300
HS Code 
2930.90.4950
Hazardous Substances Data
13073-35-3(Hazardous Substances Data)
Toxicity
rat,LD,intraperitoneal,> 1gm/kg (1000mg/kg),LIVER: OTHER CHANGESLIVER: CHANGES IN LIVER WEIGHT,Acta Pathologica Japonica. Vol. 39, Pg. 281, 1989.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E1260
Product name
L-Ethionine
Purity
≥99% (TLC)
Packaging
250mg
Price
$213
Updated
2024/03/01
Sigma-Aldrich
Product number
E1260
Product name
L-Ethionine
Purity
≥99% (TLC)
Packaging
1g
Price
$700
Updated
2024/03/01
TCI Chemical
Product number
E0039
Product name
L-Ethionine
Purity
>98.0%(T)
Packaging
100mg
Price
$71
Updated
2024/03/01
TRC
Product number
E890435
Product name
L-Ethionine
Packaging
500mg
Price
$140
Updated
2021/12/16
TRC
Product number
E890435
Product name
L-Ethionine
Packaging
5g
Price
$820
Updated
2021/12/16
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L-ETHIONINE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Ethionine-induced inhibition of protein synthesis and lowering of ATP level in the liver.

Definition

ChEBI: An S-ethylhomocysteine that has S-configuration at the chiral centre.

Biological Activity

An analog of methionine th at interferes with the normal methylation of DNA and other methylation pathways, and induces pancreatic toxicity and liver cancer. However, in animal studies, it has also been shown to act synergistically with methionine-depletion to block the growth and metastasis of methionine-dependent tumors.

Purification Methods

Likely impurities are N-acetyl-(R and S)-ethionine, S-methionine, and R-ethionine. Crystallise it from water by adding 4volumes of EtOH or 85% aqueous EtOH. It sublimes at 196-216o/0.3mm with 99.1% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Weiss & Stekol J Am Chem Soc 73 2399 1951, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2658, 2659 1961, Beilstein 4 IV 3194.]

L-ETHIONINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from L-ETHIONINE manufacturers

Career Henan Chemical Co
Product
L-ethionine 13073-35-3
Price
US $9.80/KG
Min. Order
1g
Purity
＞98%
Supply Ability
20 tons
Release date
2020-02-10

13073-35-3, L-ETHIONINERelated Search:

S-ADENOSYL-L-METHIONINE IODIDE SALT 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE L-ETHIONINE S-Adenosyl-L-methionine tosylate L-CYSTATHIONINE S-ADENOSYL-L-METHIONINE Ademetionine disulfate tosylate Spirapril FMOC-HOMOCYS(TRT)-OH L-BUTHIONINE-(S,R)-SULFOXIMINE Ethionine ester DL-Ethionine,98%,(.+/-.)-Ethionine,(+-)-ethionin D-ETHIONINE,D(-)-ETHIONINE,D-ETHIONINE 98% S-Adenosyl-L-methionine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-ETHIONINE,FMOC-L-ETHIONINE N-ALPHA-T-BUTOXYCARBONYL-L-ETHIONINE,BOC-L-ETHIONINE S-ADENOSYL-L-METHIONINE, [METHYL-14C] (2S,4R)-FMOC-4-TRITYLMERCAPTO-PYRROLIDINE-2-CARBOXYLIC ACID

  • s-ethyl-homocystein
  • s-ethyl-l-homocystein
  • L-ETHIONINE
  • L-2-AMINO-4-(ETHYLTHIO)BUTYRIC ACID
  • H-ETH-OH
  • S-ethyl-L-homocysteine
  • L -ETHIONINE 99%
  • L-ETHIONINE 98+%
  • L-ethionine L-ethionine
  • (S)-2-Amino-4-(ethylthio)butyric acid
  • [S,(+)]-2-Amino-4-(ethylthio)butyric acid
  • Butanoic acid, 2-amino-4-(ethylthio)-, (S)-
  • Butyric acid, 2-amino-4-(ethylthio)-, L-
  • L-Homocysteine, S-ethyl-
  • Nsc82393
  • (S)-2-Amino-4-(ethylthio)butanoic acid
  • 2-amino-4-(ethylthio)-butanoicaci
  • alpha-amino-gamma-(ethylmercapto)butyricacid
  • homocysteines-ethylether
  • l-butyricaci
  • L-Ethionine&gt
  • Prinomastat Impurity 7
  • 13073-35-3
  • C2H5SCH2CH2CHNH2CO2H
  • BioChemical
  • Cancer Research
  • Carcinogens
  • Amino acids methyl、ethyl、t-butyl series
  • Amino Acids & Derivatives
  • Sulfur & Selenium Compounds
  • Amino Acids 13C, 2H, 15N
  • Amino Acids