ChemicalBook > CAS DataBase List > 4-Nitro-1,3-phenylenediamine

4-Nitro-1,3-phenylenediamine

Product Name
4-Nitro-1,3-phenylenediamine
CAS No.
5131-58-8
Chemical Name
4-Nitro-1,3-phenylenediamine
Synonyms
4-NITRO-M-PHENYLENEDIAMINE;c.i.76030;3-Amino-4-nitroaniline;LABOTEST-BB LT00053760;2,4-DIAMINONITROBENZENE;4-NITRO-M-BENZENEDIAMINE;4-nitro-3-benzenediamine;4-nitro-m-phenylenediamin;4-nitro-1,3-fenylendiamin;1,3-benzenediamine,-nitro-
CBNumber
CB9434172
Molecular Formula
C6H7N3O2
Formula Weight
153.14
MOL File
5131-58-8.mol
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4-Nitro-1,3-phenylenediamine Property

Melting point:
161°C
Boiling point:
276.04°C (rough estimate)
Density 
1.3682 (rough estimate)
vapor pressure 
0.007Pa at 25℃
refractive index 
1.6500 (estimate)
solubility 
almost transparency in hot Methanol
form 
powder to crystal
pka
0.99±0.10(Predicted)
Colour Index 
76030
color 
Yellow compound in hair dyes
Water Solubility 
<0.1 g/100 mL at 20.5 ºC
BRN 
2094904
LogP
0.55
CAS DataBase Reference
5131-58-8(CAS DataBase Reference)
EPA Substance Registry System
4-Nitro-m-phenylenediamine (5131-58-8)
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Safety

Risk Statements 
22-36/38
Safety Statements 
26-36/37/39
RTECS 
ST2910000
TSCA 
Yes
HS Code 
2921.51.5000
Hazardous Substances Data
5131-58-8(Hazardous Substances Data)
Toxicity
LD50 orl-rat: 4500 mg/kg GTPZAB 35(2),42,91
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S595098
Product name
4-NITRO-1,3-PHENYLENEDIAMINE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$185
Updated
2025/07/31
Sigma-Aldrich
Product number
S595098
Product name
4-NITRO-1,3-PHENYLENEDIAMINE
Purity
AldrichCPR
Packaging
1G
Price
$179
Updated
2024/03/01
TCI Chemical
Product number
D0104
Product name
4-Nitro-1,3-phenylenediamine
Purity
>98.0%(GC)
Packaging
25g
Price
$62
Updated
2025/07/31
TRC
Product number
N491795
Product name
4-Nitro-1,3-diaminobenzene
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
N491795
Product name
4-Nitro-1,3-diaminobenzene
Packaging
5g
Price
$120
Updated
2021/12/16
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4-Nitro-1,3-phenylenediamine Chemical Properties,Usage,Production

Chemical Properties

Yellow crystal powder

Uses

4-Nitro-1,3-diaminobenzene is a general chemical reagent used in the synthesis of pharmaceuticals. Used in the synthesis of potent and selective Chk-1 inhibitors in the treatment of various cancers.

Definition

ChEBI: 4-nitro-1,3-phenylenediamine is a C-nitro compound.

General Description

Orange prisms with blue luster or yellow crystalline solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

4-Nitro-1,3-phenylenediamine is an amine/organonitrate. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Fire Hazard

Flash point data for 4-Nitro-1,3-phenylenediamine are not available, but 4-Nitro-1,3-phenylenediamine is probably combustible.

Safety Profile

Moderately toxic by ingestion.Mutation data reported. When heated to decomposition itemits toxic vapors of NOx.

4-Nitro-1,3-phenylenediamine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Nitro-1,3-phenylenediamine Suppliers

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View Lastest Price from 4-Nitro-1,3-phenylenediamine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
4-Nitro-1,3-phenylenediamine 5131-58-8
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%min
Supply Ability
1000kg
Release date
2025-09-09
Shaanxi Dideu New Materials Co. Ltd
Product
4-Nitro-1,3-phenylenediamine 5131-58-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2024-11-19
Wuhan Boyuan Import & Export Co., LTD
Product
4-Nitro-1,3-phenylenediamine 5131-58-8
Price
US $25.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000tons
Release date
2024-04-15

5131-58-8, 4-Nitro-1,3-phenylenediamineRelated Search:

4-Nitrobenzonitrile 6-Aminocaproic acid 4-Nitrotoluene m-Phenylenediamine 4-Nitrobenzoic acid ALTRENOGEST p-Phenylenediamine o-Phenylenediamine Glycine Benzene-1,3-diamine dihydrochloride 1,3-Phenylenediamine sulfate 3-Aminophenol 1,3-Diaminoguanidine monohydrochloride Tris(hydroxymethyl)aminomethane 4-Nitrophenol 2,3,6-TRINITROPHENOL DNQX NITROGEN DIOXIDE

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