4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE
- Product Name
- 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE
- CAS No.
- 343788-69-2
- Chemical Name
- 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE
- Synonyms
- 4-Amino-1-Boc-4-methylpip...;TERT-BUTYL-4-AMINO-4-METHYLPIP;1-Boc-4-AMino-4-Methylpiperidine;4-Amino-1-Boc-4-methylpiperidine;N-Boc-4-amino-4-methylpiperidine;4-AMINO-4-METHYL-1-BOC-PIPERIDINE;1-BOC-4-AMINO-4-METHYL PIPERADINE;4-AMINO-4-METHYL-N-BOC-PIPERIDINE;4-Amino-1-N-boc-4-methyl-piperidine;butyl 4-aMino-4-Methylpiperidine-1-carboxylate
- CBNumber
- CB9441604
- Molecular Formula
- C11H22N2O2
- Formula Weight
- 214.3
- MOL File
- 343788-69-2.mol
4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE Property
- Boiling point:
- 283℃
- Density
- 1.017
- Flash point:
- 125℃
- storage temp.
- 2-8°C(protect from light)
- pka
- 9.77±0.20(Predicted)
- Appearance
- Colorless to light yellow Solid-Liquid Mixture
Safety
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H341Suspected of causing genetic defects
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A3491
- Product name
- tert-Butyl 4-Amino-4-methylpiperidine-1-carboxylate
- Purity
- min. 95.0 %
- Packaging
- 1G
- Price
- $141
- Updated
- 2025/07/31
- Product number
- B415188
- Product name
- tert-Butyl4-Amino-4-methylpiperidine-1-carboxylate
- Packaging
- 250mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- W5593
- Product name
- 1-Boc-4-Amino-4-methylpiperidine
- Packaging
- 1g
- Price
- $122
- Updated
- 2021/12/16
- Product number
- FA148944
- Product name
- 4-Amino-1-N-butoxycarbonyl-4-methyl-piperidine
- Packaging
- 500mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- FA148944
- Product name
- 4-Amino-1-N-butoxycarbonyl-4-methyl-piperidine
- Packaging
- 250mg
- Price
- $80
- Updated
- 2021/12/16
4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE Chemical Properties,Usage,Production
Chemical Properties
White powder
Synthesis
236406-14-7
343788-69-2
General procedure for the synthesis of tert-butyl 4-amino-4-methylpiperidine-1-carboxylate from the compound (CAS: 236406-14-7): a mixture of the compound of formula LE (2.48 g, 7.11 mmol) with 10% palladium carbon (200 mg, Sigma-Aldrich) in methanol (20 mL) was subjected to an atmosphere of hydrogen at about 250 °C The reaction was stirred for 16 hours. Upon completion of the reaction, the Pd/C catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to give 1.37 g of the compound of formula LF as a light-colored viscous oil (90.2% yield). The structure of tert-butyl 4-amino-4-methylpiperidine-1-carboxylate, compound of formula LF, was confirmed using 1H NMR. The 1H NMR data of compound LF were as follows: δH (400 MHz, CDCl3): 3.47-3.49 (4H, m), 1.47-1.61 (4H, m), 1.46 (9H, s), 1.31-1.42 (2H, m), 1.15 (3H, s).
References
[1] Patent: WO2008/89201, 2008, A2. Location in patent: Page/Page column 234-235
[2] Journal of Medicinal Chemistry, 2012, vol. 55, # 12, p. 5901 - 5921
[3] Patent: WO2006/38006, 2006, A2. Location in patent: Page/Page column 26-27
[4] Patent: WO2009/116067, 2009, A2. Location in patent: Page/Page column 139
4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE Suppliers
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View Lastest Price from 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE manufacturers
- Product
- 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE 343788-69-2
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200
- Release date
- 2018-12-23