4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE

Product Name: 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE
CAS No.: 343788-69-2
Chemical Name: 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE
Synonyms: 4-Amino-1-Boc-4-methylpip...;TERT-BUTYL-4-AMINO-4-METHYLPIP;1-Boc-4-AMino-4-Methylpiperidine;4-Amino-1-Boc-4-methylpiperidine;N-Boc-4-amino-4-methylpiperidine;4-AMINO-4-METHYL-1-BOC-PIPERIDINE;1-BOC-4-AMINO-4-METHYL PIPERADINE;4-AMINO-4-METHYL-N-BOC-PIPERIDINE;4-Amino-1-N-boc-4-methyl-piperidine;butyl 4-aMino-4-Methylpiperidine-1-carboxylate
CBNumber: CB9441604
Molecular Formula: C11H22N2O2
Formula Weight: 214.3
MOL File: 343788-69-2.mol

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4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE Property

Boiling point:: 283℃
Density: 1.017
Flash point:: 125℃
storage temp.: 2-8°C(protect from light)
pka: 9.77±0.20(Predicted)
Appearance: Colorless to light yellow Solid-Liquid Mixture

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Safety

HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H341Suspected of causing genetic defects

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: A3491
Product name: tert-Butyl 4-Amino-4-methylpiperidine-1-carboxylate
Purity: min. 95.0 %
Packaging: 1G
Price: $141
Updated: 2025/07/31

TRC

Product number: B415188
Product name: tert-Butyl4-Amino-4-methylpiperidine-1-carboxylate
Packaging: 250mg
Price: $90
Updated: 2021/12/16

AK Scientific

Product number: W5593
Product name: 1-Boc-4-Amino-4-methylpiperidine
Packaging: 1g
Price: $122
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA148944
Product name: 4-Amino-1-N-butoxycarbonyl-4-methyl-piperidine
Packaging: 500mg
Price: $125
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA148944
Product name: 4-Amino-1-N-butoxycarbonyl-4-methyl-piperidine
Packaging: 250mg
Price: $80
Updated: 2021/12/16

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4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE Chemical Properties,Usage,Production

Chemical Properties

White powder

Synthesis

236406-14-7

343788-69-2

General procedure for the synthesis of tert-butyl 4-amino-4-methylpiperidine-1-carboxylate from the compound (CAS: 236406-14-7): a mixture of the compound of formula LE (2.48 g, 7.11 mmol) with 10% palladium carbon (200 mg, Sigma-Aldrich) in methanol (20 mL) was subjected to an atmosphere of hydrogen at about 250 °C The reaction was stirred for 16 hours. Upon completion of the reaction, the Pd/C catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to give 1.37 g of the compound of formula LF as a light-colored viscous oil (90.2% yield). The structure of tert-butyl 4-amino-4-methylpiperidine-1-carboxylate, compound of formula LF, was confirmed using 1H NMR. The 1H NMR data of compound LF were as follows: δH (400 MHz, CDCl3): 3.47-3.49 (4H, m), 1.47-1.61 (4H, m), 1.46 (9H, s), 1.31-1.42 (2H, m), 1.15 (3H, s).

References

[1] Patent: WO2008/89201, 2008, A2. Location in patent: Page/Page column 234-235
[2] Journal of Medicinal Chemistry, 2012, vol. 55, # 12, p. 5901 - 5921
[3] Patent: WO2006/38006, 2006, A2. Location in patent: Page/Page column 26-27
[4] Patent: WO2009/116067, 2009, A2. Location in patent: Page/Page column 139

4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE Suppliers

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View Lastest Price from 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE manufacturers

Career Henan Chemical Co

Product: 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE 343788-69-2
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200
Release date: 2018-12-23

343788-69-2, 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINERelated Search:

4-Amino-1-Boc-2-methylpiperidine 4-AMINO-1-BOC-PIPERIDINE-4-CARBOXYLIC ACID 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE 4-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-TERT-BUTYL ESTER 4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-TERT-BUTYL ESTER 1-Boc-4-amino-4-piperidineacetic acid TERT-BUTYL 4-[ACETYL(METHYL)AMINO]-4-PHENYLPIPERIDINE-1-CARBAMATE 4-AMINO-1-BOC-PIPERIDINE-4-CARBOXAMIDE TERT-BUTYL 4-AMINO-4-CYANOPIPERIDINE-1-CARBOXYLATE 1-T-BOC-PIPERIDINE-4-SPIRO-5'-HYDANTOIN 4-AMINO-1-N-BUTOXYCARBONYL-4-ETHYL-PIPERIDINE 1-T-BOC-PIPERIDINE-4-SPIRO-5'-[1',3'-BIS-T-BOC]-HYDANTOIN (4-FMOC-AMINO-1-BOC-PIPERIDIN-4-YL)-ACETIC ACID 1-BOC-4-[4-(METHYLSULFONYL)-2-NITROPHENYL]PIPERIDIN-4-AMINE 4-AMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 4-METHYL ESTER 4-BENZYLOXY-CARBONYL-AMINO-1-N-BUTOXY-CARBONYL-4-METHYL PIPERIDINE 4-BENZYLOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-TERT-BUTYL ESTER BOC-3-CARBOXYMETHYL-1-PHENYL-1,3,8-TRIAZASPIRO[4 5]DECAN-4-ONE

4-Amino-1-Boc-4-methylpiperidine

4-Amino-1-Boc-4-methylpip...

1-Boc-4-AMino-4-Methylpiperidine

1-Piperidinecarboxylic acid, 4-aMino-4-Methyl-, 1,1-diMethylethyl ester

1-(tert-Butoxycarbonyl)-4-amino-4-methylpiperidine

N-Boc-4-amino-4-methylpiperidine

4-AMino-4-Methyl-1-piperidinecarboxylic acid tert-butyl ester

butyl 4-aMino-4-Methylpiperidine-1-carboxylate

1-BOC-4-AMINO-4-METHYL PIPERADINE

TERT-BUTYL 4-AMINO-4-METHYLPIPERIDINE-1-CARBOXYLATE

4-AMINO-4-METHYL-1-BOC-PIPERIDINE

4-AMINO-1-N-TERT-BUTYLOXYCARBONYL-4-METHYL-PIPERIDINE

4-Amino-1-N-boc-4-methyl-piperidine

TERT-BUTYL-4-AMINO-4-METHYLPIP

4-AMINO-4-METHYL-N-BOC-PIPERIDINE

4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE

343788-69-2

43788-69-2