ChemicalBook > CAS DataBase List > O-ACETYLSALICYLOYL CHLORIDE

O-ACETYLSALICYLOYL CHLORIDE

Product Name
O-ACETYLSALICYLOYL CHLORIDE
CAS No.
5538-51-2
Chemical Name
O-ACETYLSALICYLOYL CHLORIDE
Synonyms
SKL1282;ASPIRIN CHLORIDE;AKOS BBS-00003925;2-(Chlorocarbonyl);O-ACETYLSALICYLOYL C;o-Acetylsalicychloride;Acetylsalicoyl chloride;O-Acetoxybenzoylchloride;ACETYLSALICYLOYL CHLORIDE;2-ACETOXYBENZOYL CHLORIDE
CBNumber
CB9446371
Molecular Formula
C9H7ClO3
Formula Weight
198.6
MOL File
5538-51-2.mol
More
Less

O-ACETYLSALICYLOYL CHLORIDE Property

Melting point:
45-49 °C (lit.)
Boiling point:
107-110 °C/0.1 mmHg (lit.)
Density 
1.3219 (rough estimate)
refractive index 
n20/D 1.536(lit.)
Flash point:
>230 °F
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
powder to lump
color 
White to Orange to Green
Water Solubility 
Soluble in toluene. Reacts with water.
Sensitive 
Moisture Sensitive
BRN 
880372
Stability:
Moisture Sensitive
CAS DataBase Reference
5538-51-2(CAS DataBase Reference)
NIST Chemistry Reference
Acetylsalicyloyl chloride(5538-51-2)
More
Less

Safety

Hazard Codes 
C,Xi
Risk Statements 
22-34-37-29
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
F 
3-10-21
Hazard Note 
Irritant/Corrosive/Moisture Sensitive
HazardClass 
8
PackingGroup 
II
HS Code 
29163900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
165190
Product name
O-Acetylsalicyloyl chloride
Purity
95%
Packaging
5g
Price
$51.4
Updated
2024/03/01
Sigma-Aldrich
Product number
165190
Product name
O-Acetylsalicyloyl chloride
Purity
95%
Packaging
25g
Price
$81.3
Updated
2024/03/01
TCI Chemical
Product number
A1917
Product name
O-Acetylsalicyloyl Chloride
Purity
>97.0%(HPLC)(T)
Packaging
5g
Price
$38
Updated
2024/03/01
TCI Chemical
Product number
A1917
Product name
O-Acetylsalicyloyl Chloride
Purity
>97.0%(HPLC)(T)
Packaging
25g
Price
$120
Updated
2024/03/01
Alfa Aesar
Product number
L00919
Product name
O-Acetylsalicyloyl chloride, 97%
Packaging
25g
Price
$143
Updated
2024/03/01
More
Less

O-ACETYLSALICYLOYL CHLORIDE Chemical Properties,Usage,Production

Chemical Properties

yellow to light orange chunks

Uses

O-Acetylsalicyloyl chloride was used in the synthesis of enantiomerically pure bidentate heteroorganic ligands built on simple achiral skeletons and containing an aziridine moiety. It was used in the general synthesis of acetoxybenzamides. It was used in the chemical synthesis of 2,2,6,6-tetramethyl-1-piperidinyloxy(TEMPO)-aspirin conjugate via condensation reaction with 4-hydroxy-TEMPO. It was used as reagent in acylation of cyclobutenediones.

Purification Methods

Check first the IR to see if an OH frequency is present. If so, some free acid is present. Then reflux with acetyl chloride for 2-3hours and fractionate at high vacuum. The distillate should crystallise. It can be recrystallised from hexane or *C6H6 (m 60o, sintering at 52o). [Riegel & Wittcoff J Am Chem Soc 64 486 1942, Beilstein 10 H 86, 10 I 43, 10 II 55, 10 III 151, 10 IV 169.]

O-ACETYLSALICYLOYL CHLORIDE Preparation Products And Raw materials

Raw materials

Anhydrous benzene Acetylsalicylic acid

Preparation Products

4-Hydroxycoumarin BENORILATE p-Coumaric acid
More
Less

O-ACETYLSALICYLOYL CHLORIDE Suppliers

Americas 1 Belgium 1 China 155 Europe 3 Germany 6 India 4 Japan 2 Switzerland 2 United Kingdom 10 United States 21 Global 205
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3930
Advantage
58
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18042
Advantage
56
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
7295
Advantage
60
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6767
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
13096311329 028-88469284 616445927
Fax
028-88469284
Email
616445927@qq.com
Country
China
ProdList
2874
Advantage
50
Hotechem Shanghai Co., Ltd.,
Tel
021-34621078 13120882795
Fax
021-34622517
Email
465106944@qq.com
Country
China
ProdList
856
Advantage
56
Nanjing Derno Pharmaceutical Technology Co., Ltd.
Tel
025-86957866 13952093866
Fax
025-68661287
Email
sales@dernopharm.com
Country
China
ProdList
924
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Dafeng Newti Pharmaceutical Technology Co., Ltd.
Tel
0512-62706796 13812758145
Email
2760994703@qq.com
Country
China
ProdList
276
Advantage
55
Shanghai Synchem Pharma Co., ltd
Tel
21-619849051-1 18521059765
Email
synchempharma@aliyun.com
Country
China
ProdList
6463
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9021
Advantage
60
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Guangzhou Jhd Chemical Reagent Co., Ltd.
Tel
020-84383047
Fax
020-84380294
Email
sales@jhd.com.cn
Country
China
ProdList
9186
Advantage
65
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718 +86-13336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29791
Advantage
60
Aikon International Limited
Tel
025-58851090 13611564524
Fax
(6)02557626880
Email
lwan@aikonchem.com
Country
China
ProdList
15951
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
15497
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6038 18902104717
Email
sales@heowns.com
Country
China
ProdList
21085
Advantage
60
UHN Shanghai Research & Development Co., Ltd.
Tel
021-58958002 18930822973
Fax
021-58958618
Email
xiaoyangw@gmail.com
Country
China
ProdList
2128
Advantage
58
Alchemist-pharm chemical Technology Co. Ltd.
Tel
0371-67991738 13783628208
Fax
QQ 412703949
Email
carl@alchemist-pharm.com
Country
China
ProdList
1872
Advantage
58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-51831887 15337167856
Fax
027-51837635 QQ1165326703
Email
hubeixinyuanshun@163.com
Country
China
ProdList
10295
Advantage
58
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-63315541 13323832564
Fax
QQ:3001332135
Email
3001332135@qq.com
Country
China
ProdList
9880
Advantage
58
Suzhou Sonic Biotech Co. Ltd.
Tel
18106139113
Country
China
ProdList
201
Advantage
58
Wuhan yuqing jiaheng pharmaceutical co. LTD
Tel
027-83855389 13545340383
Fax
027-83855389
Email
2586905842@qq.com
Country
China
ProdList
1417
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9639
Advantage
58
Hebei Chuanghai Biotechnology Co,.LTD
Tel
+86-13131129325
Fax
86-0311-66562153
Email
sales1@chuanghaibio.com
Country
China
ProdList
5893
Advantage
58
More
Less

View Lastest Price from O-ACETYLSALICYLOYL CHLORIDE manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
O-Acetylsalicyloyl Chloride 5538-51-2
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-19
Longyan Tianhua Biological Technology Co., Ltd
Product
O-Acetylsalicylryl chloride 5538-51-2
Price
US $10.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99
Supply Ability
999
Release date
2020-11-09
Career Henan Chemical Co
Product
O-Acetylsalicylryl chloride 5538-51-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
10 tons
Release date
2020-02-14

5538-51-2, O-ACETYLSALICYLOYL CHLORIDERelated Search:

2-HYDROXYBENZOIC-3,4,5,6-D4 ACID 5-ACETYLSALICYLIC ACID salicylacyl glucuronide Acetylsalicylic Acid-d3 BENORILATE Carbasalate calcium 4-HYDROXYBENZOIC-2,3,5,6-D4 ACID Aspirin-acyl--D-glucuronide 4-Hydroxybenzoic-1,2,3,4,5,6-13C6 Acid 2-ACETOXYBENZOIC-3,4,5,6-D4 ACID METHYL 5-ACETYLSALICYLATE Salicylic Acid b-D-O-Glucuronide MR 897 Salicylic Acid-13C6 PU 122 2-[[2-[[2-(Acetyloxy)benzoyl]oxy]benzoyl]oxy]benzoic Acid 2-[[2-[(2-carboxyphenoxy)carbonyl]phenoxy]carbonyl]phenyl Ester 1-[bis(4-fluorophenyl)methyl]-2,2,3,3,5,5,6,6-octadeuterio-4-[3-(3,4-dimethoxyphenyl)prop-2-enyl]piperazine 2-[[2-(Acetyloxy)benzoyl]oxy]benzoic Acid 2-[(2-Carboxyphenoxy)carbonyl]phenyl Ester

  • 2-(acetyloxy)-benzoylchlorid
  • 2-(Chlorocarbonyl)phenyl acetate
  • Acetylsalicoyl chloride
  • Benzoyl chloride, 2-(acetyloxy)-
  • O-Acetoxybenzoylchloride
  • o-Acetylsalicoyl chloride
  • ASPIRIN CHLORIDE
  • 2-ACETOXYBENZOYL CHLORIDE
  • ACETYLSALICYLOYL CHLORIDE
  • AKOS BBS-00003925
  • O-ACETYLSALICYLOYL CHLORIDE
  • O-Acetylsalicylryl chloride
  • O-Acetylsalicyloylchloride,98%
  • 2-Acetoxybenzoic acid chloride
  • 2-Acetyloxybenzoic acid chloride
  • 2-ACETYLSALICYLOYL CHLORIDE
  • o-Acetylsalicychloride
  • O-Acetylsalicyloyl chloride 97%
  • 2-(acetyloxy)-benzoyl chloride
  • Acetylsalicyloyl chloride,98%
  • O-ACETYLSALICYLOYL C
  • 2-Acetoxybenzoyl chloride SynonyMs: Acetylsalicyloyl chloride
  • <i>O</i>-Acetylsalicyloyl Chloride
  • 2-(Chlorocarbonyl)
  • O-acetylsalicylyl chloride
  • O-Acetylsalicyloyl Chloride &gt
  • Acetylsalicylic Acid Impurity 27
  • SKL1282
  • 2-(carbonochloridoyl)phenyl acetate
  • 5538-51-2
  • 2CH3CO2C6H4COCl
  • ACID CHLORIDE
  • Organic Building Blocks
  • Carbonyl Compounds
  • Building Blocks
  • Acid Halides
  • Acid Halides
  • Building Blocks
  • Carbonyl Compounds
  • Chemical Synthesis
  • Organic Building Blocks
  • Acid Halides
  • Carbonyl Compounds
  • Organic Building Blocks