ChemicalBook > CAS DataBase List > BTS

BTS

Product Name
BTS
CAS No.
1576-37-0
Chemical Name
BTS
Synonyms
BTS;CLN3;Battenin;NSC 37123;N-Tosylbenzylamine;N-Benzyl-p-tosylaMide;LABOTEST-BB LT00786416;N-Tosylphenylmethanamine;N-Tosylbenzenemethaneamine;n-benzyl-p-toluenesulfonamid
CBNumber
CB9457528
Molecular Formula
C14H15NO2S
Formula Weight
261.34
MOL File
1576-37-0.mol
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BTS Property

Melting point:
115 °C
Boiling point:
419.1±48.0 °C(Predicted)
Density 
1.204±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Dichloromethane, Ethyl Acetate (Slightly)
pka
11.54±0.30(Predicted)
form 
White crystalline solid
color 
White to Off-White
Sensitive 
Light Sensitive
CAS DataBase Reference
1576-37-0(CAS DataBase Reference)
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Safety

RTECS 
XT5490000
HS Code 
2935.90.9500
Toxicity
rat,LD,oral,> 500mg/kg (500mg/kg),National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 41, 1953.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
203895
Product name
BTS
Purity
A potent inhibitor of Ca
Packaging
5mg
Price
$172
Updated
2024/03/01
TCI Chemical
Product number
B3082
Product name
N-Benzyl-p-toluenesulfonamide
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$131
Updated
2024/03/01
TCI Chemical
Product number
B3082
Product name
N-Benzyl-p-toluenesulfonamide
Purity
>98.0%(HPLC)(N)
Packaging
25g
Price
$394
Updated
2024/03/01
Alfa Aesar
Product number
J64910
Product name
N-Benzyl-p-toluenesulfonamide
Packaging
5mg
Price
$117.65
Updated
2024/03/01
Alfa Aesar
Product number
J64910
Product name
N-Benzyl-p-toluenesulfonamide
Packaging
10mg
Price
$212
Updated
2024/03/01
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BTS Chemical Properties,Usage,Production

Description

BTS is an inhibitor of skeletal muscle myosin II ATPase activity that reduces the affinity of ADP-myosin for actin. It inhibits calcium-stimulated ATPase activity of rabbit muscle myosin subfragment 1 (S1) in an actin-independent manner with an IC50 value of approximately 5 μM. It is selective for calcium-stimulated myosin II over human platelet myosin II, kinesin, pyruvate kinase, and lactate dehydrogenase at 100 μM. BTS (2 μM) inhibits the activity of skeletal muscle myosin, reversibly reducing the sliding velocity of heavy meromyosin in a gliding-filament assay. It inhibits isometric calcium-activated tension in isolated fast-twitch rabbit psoas muscle fibers (IC50 = ~3 μM) but not in isolated slow-twitch rat trabeculae and papillary cardiac muscle. BTS is also an intermediate in the synthesis of sulfonamides.

Chemical Properties

White Solid

Uses

A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin interaction with F-actin. Does not affect platelet myosin II

Uses

A potent inhibitor of calcium-stimulated myosin S1 ATPase

Definition

ChEBI: 4-methyl-N-(phenylmethyl)benzenesulfonamide is a sulfonamide.

Synthesis Reference(s)

The Journal of Organic Chemistry, 28, p. 592, 1963 DOI: 10.1021/jo01037a523

Biological Activity

Selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC 50 ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle.

storage

Desiccate at RT

BTS Preparation Products And Raw materials

Raw materials

Preparation Products

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BTS Suppliers

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View Lastest Price from BTS manufacturers

Henan Fengda Chemical Co., Ltd
Product
N-Benzyl-p-toluenesulfonaMide 1576-37-0
Price
US $10.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-12
Career Henan Chemical Co
Product
BTS 1576-37-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPCL
Supply Ability
10t
Release date
2019-12-20

1576-37-0, BTSRelated Search:


  • n-benzyl-p-toluenesulfonamid
  • N-BENZYL-P-TOLUENESULFONAMIDE
  • N-BENZYL-P-TOLUENESULPHONAMIDE
  • LABOTEST-BB LT00786416
  • BTS
  • 4-METHYL-N-(PHENYLMETHYL)BENZENESULFONAMIDE
  • N-BENZYL-4-METHYL-BENZENESULFONAMIDE
  • N-Tosylbenzylamine
  • N-Methyl-N-(phenylmethyl)benzenesulfonamide
  • N-Tosylbenzenemethaneamine
  • N-Tosylphenylmethanamine
  • Benzyl(4-toluenesulfonyl)aMine
  • N-Benzyl-p-tosylaMide
  • NSC 37123
  • ANTI-CLN3 (CENTER) antibody produced in rabbit
  • Battenin
  • CLN3
  • 4-methyl-n-(phenylmethyl)-benzenesulfonamid
  • N-Benzyl-p-ToluenesulfonaMide (BTS)
  • BTS - CAS 1576-37-0 - Calbiochem
  • Benzenesulfonamide,4-methyl-N-(phenylmethyl)-
  • BTS (N-Benzyl-p-toluenesulfonamide
  • N-Benzyl-p-toluenesulfonamide &gt
  • BTS, Ca2+-stimulated myosin S1 ATPase
  • 1576-37-0
  • A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~5 μM) and reversibly blocks the gliding motility.
  • Inhibitors
  • ATPase