ChemicalBook > CAS DataBase List > BTS

BTS

Product Name: BTS
CAS No.: 1576-37-0
Chemical Name: BTS
Synonyms: BTS;CLN3;Battenin;NSC 37123;N-Tosylbenzylamine;BTS, 10 mM in DMSO;N-Benzyl-p-tosylaMide;LABOTEST-BB LT00786416;N-Tosylphenylmethanamine;N-Tosylbenzenemethaneamine
CBNumber: CB9457528
Molecular Formula: C14H15NO2S
Formula Weight: 261.34
MOL File: 1576-37-0.mol

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BTS Property

Melting point:: 115 °C
Boiling point:: 419.1±48.0 °C(Predicted)
Density: 1.204±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Dichloromethane, Ethyl Acetate (Slightly)
pka: 11.54±0.30(Predicted)
form: White crystalline solid
color: White to Off-White
Sensitive: Light Sensitive
InChI: InChI=1S/C14H15NO2S/c1-12-7-9-14(10-8-12)18(16,17)15-11-13-5-3-2-4-6-13/h2-10,15H,11H2,1H3
InChIKey: WTHKAJZQYNKTCJ-UHFFFAOYSA-N
SMILES: C1(S(NCC2=CC=CC=C2)(=O)=O)=CC=C(C)C=C1
CAS DataBase Reference: 1576-37-0(CAS DataBase Reference)

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Safety

RTECS: XT5490000
HS Code: 2935.90.9500
Toxicity: rat,LD,oral,> 500mg/kg (500mg/kg),National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 41, 1953.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 203895
Product name: BTS
Purity: A potent inhibitor of Ca
Packaging: 5mg
Price: $186
Updated: 2025/07/31

TCI Chemical

Product number: B3082
Product name: N-Benzyl-p-toluenesulfonamide
Purity: >98.0%(HPLC)(N)
Packaging: 5g
Price: $118
Updated: 2025/07/31

TCI Chemical

Product number: B3082
Product name: N-Benzyl-p-toluenesulfonamide
Purity: >98.0%(HPLC)(N)
Packaging: 25g
Price: $355
Updated: 2025/07/31

Cayman Chemical

Product number: 30099
Product name: BTS
Packaging: 1g
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 30099
Product name: BTS
Packaging: 25g
Price: $420
Updated: 2024/03/01

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BTS Chemical Properties,Usage,Production

Description

BTS is an inhibitor of skeletal muscle myosin II ATPase activity that reduces the affinity of ADP-myosin for actin. It inhibits calcium-stimulated ATPase activity of rabbit muscle myosin subfragment 1 (S1) in an actin-independent manner with an IC₅₀ value of approximately 5 μM. It is selective for calcium-stimulated myosin II over human platelet myosin II, kinesin, pyruvate kinase, and lactate dehydrogenase at 100 μM. BTS (2 μM) inhibits the activity of skeletal muscle myosin, reversibly reducing the sliding velocity of heavy meromyosin in a gliding-filament assay. It inhibits isometric calcium-activated tension in isolated fast-twitch rabbit psoas muscle fibers (IC₅₀ = ~3 μM) but not in isolated slow-twitch rat trabeculae and papillary cardiac muscle. BTS is also an intermediate in the synthesis of sulfonamides.

Chemical Properties

White Solid

Uses

A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin interaction with F-actin. Does not affect platelet myosin II

Uses

A potent inhibitor of calcium-stimulated myosin S1 ATPase

Definition

ChEBI: 4-methyl-N-(phenylmethyl)benzenesulfonamide is a sulfonamide.

Synthesis Reference(s)

The Journal of Organic Chemistry, 28, p. 592, 1963 DOI: 10.1021/jo01037a523

Biological Activity

Selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC 50 ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle.

storage

Desiccate at RT

References

[1] A. CHEUNG. A small-molecule inhibitor of skeletal muscle myosin II[J]. Nature Cell Biology, 2001, 4 1: 83-88. DOI: 10.1038/ncb734
[2] FENG SHI. Green and Efficient Synthesis of Sulfonamides Catalyzed by Nano-Ru/Fe3O4[J]. Journal of the American Chemical Society, 2009, 131 5: 1775-1779. DOI: 10.1021/ja807681v

BTS Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from BTS manufacturers

Henan Fengda Chemical Co., Ltd

Product: N-Benzyl-p-toluenesulfonaMide 1576-37-0
Price: US $10.00-0.80/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-12

Career Henan Chemical Co

Product: BTS 1576-37-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPCL
Supply Ability: 10t
Release date: 2019-12-20

1576-37-0, BTSRelated Search:

benzyl 2-oxopiperidine-1-carboxylate BTS BTS-13622 BTS 54-505 bts4054 Sibutramine Hydrochloride Monohydrate BTS 54524 bts2727 bts7 BTS-10335 bts1832 BTS 27419 BTS-49465 bts7 p-Toluenesulfonic acid 3-(4-METHOXY-PHENYL)-3-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID N-BENZOYL-4-METHYL-BENZENESULFONAMIDE N-BENZYL-N-NITROSO-P-TOLUENESULFONAMIDE

n-benzyl-p-toluenesulfonamid

N-BENZYL-P-TOLUENESULFONAMIDE

N-BENZYL-P-TOLUENESULPHONAMIDE

LABOTEST-BB LT00786416

BTS

4-METHYL-N-(PHENYLMETHYL)BENZENESULFONAMIDE

N-BENZYL-4-METHYL-BENZENESULFONAMIDE

N-Tosylbenzylamine

N-Methyl-N-(phenylmethyl)benzenesulfonamide

N-Tosylbenzenemethaneamine

N-Tosylphenylmethanamine

Benzyl(4-toluenesulfonyl)aMine

N-Benzyl-p-tosylaMide

NSC 37123

ANTI-CLN3 (CENTER) antibody produced in rabbit

Battenin

CLN3

4-methyl-n-(phenylmethyl)-benzenesulfonamid

N-Benzyl-p-ToluenesulfonaMide (BTS)

BTS - CAS 1576-37-0 - Calbiochem

Benzenesulfonamide,4-methyl-N-(phenylmethyl)-

BTS (N-Benzyl-p-toluenesulfonamide

N-Benzyl-p-toluenesulfonamide &gt

BTS, Ca2+-stimulated myosin S1 ATPase

N-Benzyl-p-toluenesulfonic acid amine

BTS, 10 mM in DMSO

1576-37-0

A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~5 μM) and reversibly blocks the gliding motility.

Inhibitors

ATPase