ChemicalBook > CAS DataBase List > IONOMYCIN CALCIUM SALT

IONOMYCIN CALCIUM SALT

Product Name
IONOMYCIN CALCIUM SALT
CAS No.
56092-82-1
Chemical Name
IONOMYCIN CALCIUM SALT
Synonyms
ATCC 31005;Ionomycin,Ion;IONOMYCIN (CA);SQ23377 calcium;IONOMYCIN CA-SALT;ionomycin calcium;Calcium ionomycin.;Ionomycin Ca2+ salt;IONOMYCIN CALCIUM SALT;IONOMYCIN CALCIUM SALT 1MG
CBNumber
CB9458893
Molecular Formula
C41H70CaO9
Formula Weight
747.07
MOL File
56092-82-1.mol
More
Less

IONOMYCIN CALCIUM SALT Property

Melting point:
205-206 C
Flash point:
87 °C
storage temp. 
−20°C
solubility 
Soluble in DMSO (10mg/ml). Also soluble in ethanol or methanol
form 
White to off-white solid
color 
white to off-white
Sensitive 
Light Sensitive
BRN 
1416163
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
WGK Germany 
3
RTECS 
NO0650000
HazardClass 
3
HS Code 
29419090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I0634
Product name
Ionomycin calcium salt from Streptomyces conglobatus
Purity
powder, ≥98% (HPLC)
Packaging
1mg
Price
$163
Updated
2024/03/01
Sigma-Aldrich
Product number
I0634
Product name
Ionomycin calcium salt from Streptomyces conglobatus
Purity
powder, ≥98% (HPLC)
Packaging
5mg
Price
$711
Updated
2024/03/01
Sigma-Aldrich
Product number
407952
Product name
Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem
Purity
Ionomycin, Calcium Salt, Streptomyces conglobatus, CAS 56092-82-1, is useful in cell activation experiments when calcium dose-response data are not required.
Packaging
5mg
Price
$470
Updated
2022/05/15
Alfa Aesar
Product number
J67343
Product name
Ionomycin calcium salt, 1 mg/ml in methanol, sterile-filtered
Packaging
1ml
Price
$423
Updated
2024/03/01
Alfa Aesar
Product number
J60628
Product name
Ionomycin calcium salt, 99%
Packaging
5mg
Price
$193
Updated
2023/06/20
More
Less

IONOMYCIN CALCIUM SALT Chemical Properties,Usage,Production

Description

Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 μM. Ionomycin (5 μM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination with phorbol 12-myristate 13-acetate (PMA; ) has commonly been used to induce the proliferation and activation of T cells, as well as to stimulate cytokine production in macrophages, in vitro.

Chemical Properties

Powder

Uses

Ionomycin is more effectivethan A23187 as a Ca++ionophore; Ionomycin is used in research on Ca++ transport across biological membranes; Ionomycin induces apoptotic degeneration of embryonic cortical neurons.

Uses

Ionomycin calcium salt is used as a polyether antibiotic and apoptotic degeneration inducer. Ionomycin induces apoptotic degeneration of embryonic cortical neurons and cell cycle arrest at G1 phase. It is more effective than A23187 (sc-3591) and provides a useful tool for increasing intracellular Ca2+ concentration.

General Description

Useful in cell activation experiments when calcium dose-response data are not required. Also available as a 10 mM solution in DMSO (Cat. No. 407953).

Biological Activity

Calcium ionophore; more specific than A23187 (5-(Methylamino)-2-[[2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid ).

Biochem/physiol Actions

Product does not compete with ATP.

storage

-20°C

References

Liu et al. (1978), Ionomycin, a new polyether antibiotic; J. Antibiot., 31 815 Liu and Hermann et al. (1978), Characterization of ionomycin as a calcium ionophore; J. Biol.Chem, 253 5892

IONOMYCIN CALCIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

IONOMYCIN CALCIUM SALT Suppliers

China 105 Germany 4 India 2 Japan 3 Switzerland 2 United Kingdom 6 United States 21 Global 143
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Greenherbs Science and Technology Development Co., Ltd.
Tel
010-61136123
Fax
+86 (10) 8857-9127
Email
pub02@greenherbs.com.cn
Country
China
ProdList
4049
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
15497
Advantage
58
Jinan Yaoyan Pharmaceutical Co., Ltd.
Tel
Fax
-
Email
jnyaoyan@163.com
Country
China
ProdList
3069
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Beijing OKA biological technology co., LTD
Tel
010-010-010-62971590 18548936886
Fax
010-62340519
Email
jack@oka-vip.com
Country
China
ProdList
6897
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
Hubei Ipure Biology Co., Ltd
Tel
+8613367258412
Fax
18062427325
Email
ada@ipurechemical.com
Country
China
ProdList
10319
Advantage
58
HONG KONG IPURE BIOLOGY CO.,LIMITED
Tel
86 18062405514 18062405514
Email
ada@ipurechemical.com
Country
CHINA
ProdList
3461
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29811
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-87569266 15319487004
Fax
029-88380327
Email
1015@dideu.com
Country
China
ProdList
4084
Advantage
58
Shanghai Zeye Biotechnology Co., Ltd.
Tel
021-61998551 13122364865
Email
sale1@shzysw.net
Country
China
ProdList
9772
Advantage
58
Guangzhou Younan Technology Co., Ltd
Tel
020-82000279 18988968278
Fax
QQ：3283937693
Email
sales@ubiochem.com
Country
China
ProdList
4297
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
wulan@absin.cn
Country
China
ProdList
24731
Advantage
58
Beijing Aomi Jiade Pharmaceutical Technology Co., Ltd
Tel
+86-13522808617 +86-13522808617
Email
omichem@126.com
Country
China
ProdList
9211
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
029-81145920 13259709322
Fax
029-88380327
Email
1027@dideu.com
Country
China
ProdList
10009
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 13675144456
Fax
025-85563444
Email
sean.lv@synzest.com
Country
China
ProdList
11438
Advantage
58
Wuhan Yanzhe Technology Co., Ltd
Tel
15527250409
Fax
QQ：2692360204
Email
wenhaotian12@163.com
Country
China
ProdList
4495
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Lingyuan Bebiansen Biological Technology Co., Ltd
Tel
18642120371
Email
2837458851@qq.com
Country
China
ProdList
7995
Advantage
58
Abmole Bioscience Inc.
Tel
021-50967598 02150967598
Email
sales@abmole.cn
Country
China
ProdList
4494
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
13774214275
Email
zhouzz@univ-bio.com
Country
China
ProdList
24990
Advantage
58
Nantong Feiyu Biological Technology CO.,LTD
Tel
0513-68819626; 15152877458
Fax
0513-68669626
Email
feiyubio@163.com
Country
China
ProdList
4819
Advantage
58
amyjetsci
Tel
027-59626688 18771149750
Email
sales@amyjet.com
Country
China
ProdList
3003
Advantage
58
Hu' nan Yunbang Pharmaceutical Co., Ltd.
Tel
0731-85561037 15386497078
Email
yunbang@yunbangapi.com
Country
China
ProdList
4827
Advantage
58
JiangSu Star Science Co.,Ltd
Tel
400-400-605-7200-7200 17312445705
Email
sales022@b2star.com
Country
China
ProdList
3761
Advantage
58
Shanghai klamar Reagent Co., LTD
Tel
4001650900 13817534909
Email
3003940895@qq.com
Country
China
ProdList
10720
Advantage
58
Hubei Aiputi Bioengineering Co., Ltd.
Tel
17762444226
Email
d17762444226@163.com
Country
China
ProdList
2402
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Email
market03@meryer.com
Country
China
ProdList
27987
Advantage
58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
Tel
021-59167510 18117107507
Email
vip@med-life.cn
Country
China
ProdList
4997
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12005
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9272
Advantage
58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
Tel
+8613817748580
Fax
021-50175322
Email
cooperation@kean-chem.com
Country
China
ProdList
40066
Advantage
58
Shanghai Acmec Biochemical Technology Co., Ltd.
Tel
+undefined18621343501
Email
product@acmec-e.com
Country
China
ProdList
33338
Advantage
58
LEAPCHEM CO., LTD.
Tel
+86-852-30606658
Email
market18@leapchem.com
Country
China
ProdList
43340
Advantage
58
More
Less

View Lastest Price from IONOMYCIN CALCIUM SALT manufacturers

Career Henan Chemical Co
Product
IONOMYCIN CALCIUM SALT 56092-82-1
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2019-12-25

56092-82-1, IONOMYCIN CALCIUM SALTRelated Search:

(+/-)-Verapamil hydrochloride AFC Felodipine D-ERYTHRO-SPHINGOSINE-1-PHOSPHATE Streptomyces albulus Roxithromycin IONOMYCIN CALCIUM SALT,READY-MADE SOLUT 1,7-HEXADECADIENE 10TR-PENTADECENOIC ACID 1,7-TETRADECADIENE cis-2,5-Bishydroxymethyl-tetrahydrofuran IONOMYCIN CALCIUM SALT ionomycin calcium salt from streptomyces conglobatus

  • Calcium ionomycin.
  • Ionomycin Ca<sup>2+</sup> Salt
  • Ionomycin Ca2+ salt
  • (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoicacidcalciumsalt
  • Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem
  • IONOMYCIN CALCIUM (SQ23377 CALCIUM)
  • ATCC 31005
  • IONOMYCIN (CA)
  • IONOMYCIN CALCIUM SALT
  • IONOMYCIN, CALCIUM SALT, STREPTOMYCES CONGLOBATUS
  • IONOMYCIN CA-SALT
  • ionomycin calcium
  • 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-(2S,2R,5S,5S)-octahydro-5-(1R)-1-hydroxyethyl-2,5-dimethyl2,2-bifuran-5-yl-9-oxo-, calcium salt (1:1), (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-
  • Ionomycin,Ion
  • SQ23377 calcium
  • IONOMYCIN CALCIUM SALT 1MG
  • 56092-82-1
  • C41H70CaO9
  • C41H72O9Ca
  • C41H70O9Ca
  • Ion Channels
  • antibiotic
  • Antibiotic Ready Made SolutionsResearch Essentials
  • Antibiotics
  • Antibiotics A to
  • Antibiotics G-MAntibiotics
  • AntibioticsAntibiotics
  • Chemical Structure Class
  • Core Bioreagents
  • Miscellaneous