IONOMYCIN CALCIUM SALT

ChemicalBook > CAS DataBase List > IONOMYCIN CALCIUM SALT

IONOMYCIN CALCIUM SALT

Product Name: IONOMYCIN CALCIUM SALT
CAS No.: 56092-82-1
Chemical Name: IONOMYCIN CALCIUM SALT
Synonyms: ATCC 31005;Ionomycin,Ion;IONOMYCIN (CA);SQ23377 calcium;IONOMYCIN CA-SALT;ionomycin calcium;Calcium ionomycin.;Ionomycin Ca2+ salt;IONOMYCIN CALCIUM SALT;IONOMYCIN CALCIUM SALT 1MG
CBNumber: CB9458893
Molecular Formula: C41H70CaO9
Formula Weight: 747.07
MOL File: 56092-82-1.mol

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IONOMYCIN CALCIUM SALT Property

Melting point:: 205-206 C
Flash point:: 87 °C
storage temp.: −20°C
solubility: Soluble in DMSO (10mg/ml). Also soluble in ethanol or methanol
form: White to off-white solid
color: white to off-white
Sensitive: Light Sensitive
BRN: 1416163
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 36
WGK Germany: 3
RTECS: NO0650000
HazardClass: 3
HS Code: 29419090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: I0634
Product name: Ionomycin calcium salt from Streptomyces conglobatus
Purity: powder, ≥98% (HPLC)
Packaging: 1mg
Price: $163
Updated: 2024/03/01

Sigma-Aldrich

Product number: I0634
Product name: Ionomycin calcium salt from Streptomyces conglobatus
Purity: powder, ≥98% (HPLC)
Packaging: 5mg
Price: $711
Updated: 2024/03/01

Sigma-Aldrich

Product number: 407952
Product name: Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem
Purity: Ionomycin, Calcium Salt, Streptomyces conglobatus, CAS 56092-82-1, is useful in cell activation experiments when calcium dose-response data are not required.
Packaging: 5mg
Price: $470
Updated: 2022/05/15

Alfa Aesar

Product number: J67343
Product name: Ionomycin calcium salt, 1 mg/ml in methanol, sterile-filtered
Packaging: 1ml
Price: $423
Updated: 2024/03/01

Alfa Aesar

Product number: J60628
Product name: Ionomycin calcium salt, 99%
Packaging: 5mg
Price: $193
Updated: 2023/06/20

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IONOMYCIN CALCIUM SALT Chemical Properties,Usage,Production

Description

Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 μM. Ionomycin (5 μM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination with phorbol 12-myristate 13-acetate (PMA; ) has commonly been used to induce the proliferation and activation of T cells, as well as to stimulate cytokine production in macrophages, in vitro.

Chemical Properties

Powder

Uses

Ionomycin is more effectivethan A23187 as a Ca++ionophore; Ionomycin is used in research on Ca++ transport across biological membranes; Ionomycin induces apoptotic degeneration of embryonic cortical neurons.

Uses

Ionomycin calcium salt is used as a polyether antibiotic and apoptotic degeneration inducer. Ionomycin induces apoptotic degeneration of embryonic cortical neurons and cell cycle arrest at G1 phase. It is more effective than A23187 (sc-3591) and provides a useful tool for increasing intracellular Ca2+ concentration.

General Description

Useful in cell activation experiments when calcium dose-response data are not required. Also available as a 10 mM solution in DMSO (Cat. No. 407953).

Biological Activity

Calcium ionophore; more specific than A23187 (5-(Methylamino)-2-[[2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid ).

Biochem/physiol Actions

Product does not compete with ATP.

storage

-20°C

References

Liu et al. (1978), Ionomycin, a new polyether antibiotic; J. Antibiot., 31 815 Liu and Hermann et al. (1978), Characterization of ionomycin as a calcium ionophore; J. Biol.Chem, 253 5892

IONOMYCIN CALCIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from IONOMYCIN CALCIUM SALT manufacturers

Career Henan Chemical Co

Product: IONOMYCIN CALCIUM SALT 56092-82-1
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2019-12-25

56092-82-1, IONOMYCIN CALCIUM SALTRelated Search:

(+/-)-Verapamil hydrochloride AFC Felodipine D-ERYTHRO-SPHINGOSINE-1-PHOSPHATE Streptomyces albulus Roxithromycin IONOMYCIN CALCIUM SALT,READY-MADE SOLUT 1,7-HEXADECADIENE 10TR-PENTADECENOIC ACID 1,7-TETRADECADIENE cis-2,5-Bishydroxymethyl-tetrahydrofuran IONOMYCIN CALCIUM SALT ionomycin calcium salt from streptomyces conglobatus

Calcium ionomycin.

Ionomycin Ca<sup>2+</sup> Salt

Ionomycin Ca2+ salt

(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoicacidcalciumsalt

Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem

IONOMYCIN CALCIUM (SQ23377 CALCIUM)

ATCC 31005

IONOMYCIN (CA)

IONOMYCIN CALCIUM SALT

IONOMYCIN, CALCIUM SALT, STREPTOMYCES CONGLOBATUS

IONOMYCIN CA-SALT

ionomycin calcium

10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-(2S,2R,5S,5S)-octahydro-5-(1R)-1-hydroxyethyl-2,5-dimethyl2,2-bifuran-5-yl-9-oxo-, calcium salt (1:1), (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-

Ionomycin,Ion

SQ23377 calcium

IONOMYCIN CALCIUM SALT 1MG

56092-82-1

C41H70CaO9

C41H72O9Ca

C41H70O9Ca

Ion Channels

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