4-METHOXY-3-NITROANILINE
- Product Name
- 4-METHOXY-3-NITROANILINE
- CAS No.
- 577-72-0
- Chemical Name
- 4-METHOXY-3-NITROANILINE
- Synonyms
- 3-NITRO-P-ANISIDINE;4-METHOXY-3-NITROANI;4-METHOXY-3-NITROANILINE;3-Nitro-p-anisidine (NH2=1);4-Methoxy-3-nitrobenzenamine;Benzenamine, 4-methoxy-3-nitro-;3-Nitro-4-methoxybenzene-1-amine;4-METHOXY-3-NITROANILINE ISO 9001：2015 REACH;4-Methoxy-3-nitroaniline@100 μg/mL in Methanol;4-Amino-2-nitroanisole, 5-Amino-2-methoxynitrobenzene
- CBNumber
- CB9462814
- Molecular Formula
- C7H8N2O3
- Formula Weight
- 168.15
- MOL File
- 577-72-0.mol
4-METHOXY-3-NITROANILINE Property
- Melting point:
- 46-47 °C
- Boiling point:
- 356.9±22.0 °C(Predicted)
- Density
- 1.318±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- Acetonitrile (Slightly), Chloroform (Slightly)
- form
- Solid
- pka
- 3.33±0.10(Predicted)
- color
- Dark Red
- InChI
- InChI=1S/C7H8N2O3/c1-12-7-3-2-5(8)4-6(7)9(10)11/h2-4H,8H2,1H3
- InChIKey
- RUFOHZDEBFYQSV-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(OC)C([N+]([O-])=O)=C1
- CAS DataBase Reference
- 577-72-0(CAS DataBase Reference)
- NIST Chemistry Reference
- P-anisidine, 3-nitro-,(577-72-0)
Safety
- Hazard Codes
- Xi
- Hazard Note
- Irritant
- HS Code
- 2922290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M327203
- Product name
- 4-Methoxy-3-nitroaniline
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-W002411
- Product name
- 4-Methoxy-3-nitroaniline
- Purity
- 99.71%
- Packaging
- 5g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- CS-W002411
- Product name
- 4-Methoxy-3-nitroaniline
- Purity
- 99.71%
- Packaging
- 10g
- Price
- $79
- Updated
- 2021/12/16
- Product number
- OR0934
- Product name
- 4-Methoxy-3-nitroaniline
- Packaging
- 5g
- Price
- $105
- Updated
- 2021/12/16
- Product number
- 4655-1-W8
- Product name
- 4-Methoxy-3-nitroaniline
- Packaging
- 5G
- Price
- $116
- Updated
- 2021/12/16
4-METHOXY-3-NITROANILINE Chemical Properties,Usage,Production
Chemical Properties
orange red solid
Uses
4-Methoxy-3-nitroaniline is a chemical compound that has been shown to have anti-tumor and anti-inflammatory effects. It belongs to the class of amines and can be synthesized by nitrating 4-methoxy aniline.
Synthesis
119-34-6
74-88-4
577-72-0
2-Nitro-4-aminophenol (10.0 g, 64.9 mmol) was used as starting material and mixed with cesium carbonate (21 g, 64 mmol) and iodomethane (9.22 g, 64.9 mmol) in acetonitrile (1500 mL). The reaction mixture was heated to reflux for 5 hours. After completion of the reaction, the mixture was cooled to room temperature and filtered to remove insoluble solids. The filtrate was concentrated under reduced pressure to remove the solvent, and the resulting crude product was purified by fast column chromatography (eluent: chloroform) to give 5.03 g of 4-methoxy-3-nitroaniline in 46% yield as a red oil. The structure of the product was confirmed by 1H NMR (DMSO-d6) δ 7.09-7.03 (m, 2H), 6.87 (d, J=3Hz, 1H), 5.21 (bs, 2H), 3.77 (s, 3H) and HRMS (EI) m/z 168.0497 (M+1). Elemental analysis results (C7H8N2O3): calculated values C 50.00, H 4.80, N 16.66; measured values C 50.20, H 5.07, N 16.60.
References
[1] Patent: US2002/26052, 2002, A1
4-METHOXY-3-NITROANILINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-METHOXY-3-NITROANILINE manufacturers
- Product
- 4-METHOXY-3-NITROANILINE 577-72-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2018-08-09